Protein Alignment CG11811 and MPP2

DIOPT Version :9

• Sequence 1: NP_648408.1
• Gene: CG11811 / 39213
• FlyBaseID: FBgn0036099
• Length: 233
• Species: Drosophila melanogaster
• Sequence 2: XP_011523129.2
• Gene: MPP2 / 4355
• HGNCID: 7220
• Length: 630
• Species: Homo sapiens
• Alignment Length: 248
• Identity: 65/248 - (26%)
• Similarity: 112/248 - (45%)
• Gaps: 45/248 - (18%)

  Fly     8 VNRALSSSSSSSSAAASLTSKKM-----------------------TAPGP----RPLVLCGPSG 45
            |.|.|..:.:|.:...||:.||.                       .|..|    :.|||.|..|
Human   374 VKRDLELTPNSGTLCGSLSGKKKKRMMYLTTKNAEFDRHELLIYEEVARMPPFRRKTLVLIGAQG 438

  Fly    46 SGKSTLLKRLFAEFPSTFGFSISHTTRKPREGEEHGVHYYFVERPEMEAAIAGDEFIETAEFTGN 110
            .|:.:|..:|....|..:|.::.:|:|:|::.|..|..|.||.|.||||.:....::|..|:.||
Human   439 VGRRSLKNKLIMWDPDRYGTTVPYTSRRPKDSEREGQGYSFVSRGEMEADVRAGRYLEHGEYEGN 503

  Fly   111 LYGTSKAAVREIQAQGRVCILDIEQKGVEQIKRTDLNPILIFNNPPSIKELERRLRKRGSE---- 171
            ||||...::|.:.|.|:||:||:..:.|:.::..:..|.::|...|..:.| |.:.:...|
Human   504 LYGTRIDSIRGVVAAGKVCVLDVNPQAVKVLRTAEFVPYVVFIEAPDFETL-RAMNRAALESGIS 567

  Fly   172 ----TEESLSKRL-NAAQVELDYG------LTPGNFHKIINNVDIDVAYEEFR 213
                ||..|.:.: .:::::..||      |...|..:...  ::..|.|:.|
Human   568 TKQLTEADLRRTVEESSRIQRGYGHYFDLCLVNSNLERTFR--ELQTAMEKLR 618

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11811	NP_648408.1	Guanylate_kin	34..219	CDD:279019	56/199 (28%)
		guanyl_kin	36..216	CDD:213788	55/193 (28%)
MPP2	XP_011523129.2	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0194
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810