DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11811 and mpp2b

DIOPT Version :9

Sequence 1:	NP_648408.1	Gene:	CG11811 / 39213	FlyBaseID:	FBgn0036099	Length:	233	Species:	Drosophila melanogaster
Sequence 2:	XP_005156123.1	Gene:	mpp2b / 431770	ZFINID:	ZDB-GENE-040704-70	Length:	561	Species:	Danio rerio

Alignment Length:	202	Identity:	58/202 - (28%)
Similarity:	101/202 - (50%)	Gaps:	11/202 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 RPLVLCGPSGSGKSTLLKRLFAEFPSTFGFSISHTTRKPREGEEHGVHYYFVERPEMEAAIAGDE 100
            :.|||.|..|.|:.:|..:|....|..:|.:..:|:|||:..|:.|..|.|:.|.|||..|....
Zfish   360 KTLVLIGAQGVGRRSLKNKLLVSDPHRYGTTTPYTSRKPKVDEKEGQMYLFMSRSEMETDIKCGR 424

  Fly   101 FIETAEFTGNLYGTSKAAVREIQAQGRVCILDIEQKGVEQIKRTDLNPILIFNNPPS---IKELE 162
            |:|..|:.||||||...::.|:...|::||||:..:.::.::..:..|.::|...|:   :|::.
Zfish   425 FLEHGEYDGNLYGTKIDSIHEVVDSGKICILDVNPQALKVLRTAEFLPYVVFIEAPNFEVLKDMN 489

  Fly   163 RRLRKRGSETEESLSKRL-----NAAQVELDYGLTPGNFHKIINNVDIDVAYEEFRNFVVQELKE 222
            |...:.|..|::.....|     .:.:::..|.   ..|...|.|.::|.||...|..:.:...:
Zfish   490 RSAIEAGVVTKQMTDSELKRTVDESERIQRAYS---HYFDLSIVNDNLDGAYRSLRRALDRLNTD 551

  Fly   223 QQKQGVS 229
            ||...||
Zfish   552 QQWVPVS 558

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11811	NP_648408.1	Guanylate_kin	34..219	CDD:279019	54/190 (28%)
CG11811	NP_648408.1	guanyl_kin	36..216	CDD:213788	54/187 (29%)
mpp2b	XP_005156123.1	L27	76..127	CDD:280918
		PDZ_signaling	148..226	CDD:238492
		SH3_MPP2	239..297	CDD:212970
		Guanylate_kin	358..546	CDD:279019	54/188 (29%)
		GuKc	368..546	CDD:214504	50/180 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0194
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810