DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11811 and metro

DIOPT Version :9

Sequence 1:	NP_648408.1	Gene:	CG11811 / 39213	FlyBaseID:	FBgn0036099	Length:	233	Species:	Drosophila melanogaster
Sequence 2:	NP_610642.2	Gene:	metro / 36176	FlyBaseID:	FBgn0050021	Length:	595	Species:	Drosophila melanogaster

Alignment Length:	239	Identity:	73/239 - (30%)
Similarity:	104/239 - (43%)	Gaps:	47/239 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 LSSSSSSSSAAASLTSKKM------------------------TAPGP-RPLVLCGPSGSGKSTL 51
            |.:|||:||.....|.|.|                        ..||. ||:||.|..|.|::.|
  Fly   341 LPASSSTSSCRQPKTKKIMYDLTENDDFDREQIATYEEVAKLYPRPGVFRPIVLIGAPGVGRNEL 405

  Fly    52 LKRLFAEFPSTFGFSISHTTRKPREGEEHGVHYYFVERPEMEAAIAGDEFIETAEFTGNLYGTSK 116
            .:||.|..|..|...:.:|||..|.||..|..|.||.|.:|:|.|...:|:|..|:.|:|||||.
  Fly   406 RRRLIARDPEKFRSPVPYTTRPMRTGEVAGREYIFVAREKMDADIEAGKFVEHGEYKGHLYGTSA 470

  Fly   117 AAVREIQAQGRVCILDIEQKGVEQIKRTDLNPILIFNNPPSIKEL-----ERRLRKRGSE----- 171
            .:|:.|...|.||:|....:.::.::...|.|.||...||.:..|     |.|.:....|
  Fly   471 ESVKSIVNAGCVCVLSPHYQAIKTLRTAQLKPFLIHVKPPELDILKATRTEARAKSTFDEANARS 535

  Fly   172 -TEESLSKRLNAAQ-----------VELDYGLTPGNFHKIINNV 203
             |:|.....:.:|:           |||..|.....|.:::.||
  Fly   536 FTDEEFEDMIKSAERIDFLYGHFFDVELVNGELVNAFEQLVQNV 579

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11811	NP_648408.1	Guanylate_kin	34..219	CDD:279019	63/193 (33%)
CG11811	NP_648408.1	guanyl_kin	36..216	CDD:213788	62/190 (33%)
metro	NP_610642.2	L27	17..68	CDD:197794
		L27	75..127	CDD:197794
		PDZ_signaling	139..229	CDD:238492
		SH3_MPP	243..302	CDD:212796
		Guanylate_kin	390..575	CDD:279019	60/184 (33%)
		GuKc	399..580	CDD:214504	57/181 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0194
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810