DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11811 and mpp1

DIOPT Version :9

Sequence 1:	NP_648408.1	Gene:	CG11811 / 39213	FlyBaseID:	FBgn0036099	Length:	233	Species:	Drosophila melanogaster
Sequence 2:	NP_999857.1	Gene:	mpp1 / 325542	ZFINID:	ZDB-GENE-031113-4	Length:	468	Species:	Danio rerio

Alignment Length:	178	Identity:	46/178 - (25%)
Similarity:	90/178 - (50%)	Gaps:	13/178 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 KMTAPGPRPLVLCGPSGSGKSTLLKRLFAEFPSTFGFSISHTTRKPREGEEHGVHYYFVERPEME 93
            ::.|...:.|||.|..|.|:|.:...|.:::|..|.:...||||..::.||:|..|||:...||.
Zfish   278 RLPAFNRKTLVLIGAHGVGRSLIKNSLLSKYPEKFAYPAPHTTRPQKKDEENGKEYYFISNDEMT 342

  Fly    94 AAIAGDEFIETAEFTGNLYGTSKAAVREIQAQGRVCILDIEQKGVEQIKRTDLNPILIFNNPPSI 158
            ..|.|::.:|...:.|:::||....:.:|..||::.:||:|.:.::.::..:..|::||..|.:.
Zfish   343 KGIVGNKLLEYGSYQGHMFGTKIETIHKIHEQGKIAVLDVEPQTLKVLRTAEFAPLVIFIAPTNT 407

  Fly   159 KELERRLRKRGSETEESLSKRLNAAQVELDYGLTPGNFHKIINNVDID 206
            ......::....|::..|:...:.             |.:|:.|.|:|
Zfish   408 GNQSEAVQNIQKESDSLLAAHRHF-------------FDEILVNNDVD 442

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11811	NP_648408.1	Guanylate_kin	34..219	CDD:279019	45/173 (26%)
CG11811	NP_648408.1	guanyl_kin	36..216	CDD:213788	45/171 (26%)
mpp1	NP_999857.1	PDZ	73..151	CDD:278991
		SH3_MPP1	164..225	CDD:213013
		Guanylate_kin	284..453	CDD:279019	45/172 (26%)
		GuKc	293..453	CDD:214504	41/163 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910