DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11811 and dlg1

DIOPT Version :9

Sequence 1:	NP_648408.1	Gene:	CG11811 / 39213	FlyBaseID:	FBgn0036099	Length:	233	Species:	Drosophila melanogaster
Sequence 2:	NP_001162718.1	Gene:	dlg1 / 32083	FlyBaseID:	FBgn0001624	Length:	1030	Species:	Drosophila melanogaster

Alignment Length:	207	Identity:	44/207 - (21%)
Similarity:	79/207 - (38%)	Gaps:	52/207 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 LSSSSSSSSA-----AASLTSKKMTAPGPR----PLVLCGPSGSGKSTLLKRLFAE--------F 59
            |::|.|.|..     |..:.:.:.|.||.|    .::...|.|:.::...:.:..|        .
  Fly   686 LATSQSQSQVHQQQHATPMVNSQSTEPGSRYASTNVLAAVPPGTPRAVSTEDITREPRTITIQKG 750

  Fly    60 PSTFGFSISHTTRKPREGEE-HGVHYYFVER-------PEMEAAIAGDEFIETAEFTGNL-YGTS 115
            |...||:|.       .||: .|::..|:..       .|::   .||:.:.....  || :.|.
  Fly   751 PQGLGFNIV-------GGEDGQGIYVSFILAGGPADLGSELK---RGDQLLSVNNV--NLTHATH 803

  Fly   116 KAAVREIQAQGRVCILDIEQKGVEQIKRTDLNPILIFNNPPSIKELERR--LRKRGSET-EESLS 177
            :.|.:.::..|.|..| :.|...|:..|.:..          |:||:::  |...||.| ..:..
  Fly   804 EEAAQALKTSGGVVTL-LAQYRPEEYNRFEAR----------IQELKQQAALGAGGSGTLLRTTQ 857

  Fly   178 KRLNAAQVELDY 189
            ||....:...||
  Fly   858 KRSLYVRALFDY 869

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11811	NP_648408.1	Guanylate_kin	34..219	CDD:279019	37/180 (21%)
CG11811	NP_648408.1	guanyl_kin	36..216	CDD:213788	36/178 (20%)
dlg1	NP_001162718.1	L27_1	303..359	CDD:286187
		PDZ	454..540	CDD:214570
		PDZ_signaling	566..655	CDD:238492
		PDZ_signaling	742..820	CDD:238492	18/90 (20%)
		SH3_DLG-like	862..922	CDD:212795	2/8 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0194
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810