DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11811 and mpp7a

DIOPT Version :9

Sequence 1:	NP_648408.1	Gene:	CG11811 / 39213	FlyBaseID:	FBgn0036099	Length:	233	Species:	Drosophila melanogaster
Sequence 2:	XP_021335692.1	Gene:	mpp7a / 30166	ZFINID:	ZDB-GENE-991209-8	Length:	621	Species:	Danio rerio

Alignment Length:	223	Identity:	66/223 - (29%)
Similarity:	109/223 - (48%)	Gaps:	39/223 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 RPLVLCGPSGSGKSTLLKRLFAEFPSTFGFSISHTTRKPREGEEHGVHYYFVERPEMEAAIAGDE 100
            |.:||.||:|.|.:.|.::|.......|..:|.||:|..|..|..||.|:|:.:...||.|..::
Zfish   395 RLVVLVGPTGVGLNELKRKLLISDTQHFSVTIPHTSRSKRHQESEGVEYHFISKNLFEADIQNNK 459

  Fly   101 -------------------FIETAEFTGNLYGTSKAAVREIQAQGRVCILDIEQKGVEQIKRTDL 146
                               |||..|:.||.||||..:||.:.::.:||:||::...::.::..:.
Zfish   460 KSGYSCFWRSSLPVLQRNRFIEHGEYKGNYYGTSFDSVRSVLSKNKVCLLDVQPHTLKHLRTAEF 524

  Fly   147 NPILIFNNPPSIKELERRLR----------KRGSE--TEESLSKRLNAAQ-VELDYGLTPGNFHK 198
            .|.::|..||.|:.|....|          |..|:  :||...:.::|:| :|..||..   |.|
Zfish   525 KPYVVFVKPPCIERLRETRRNAKVISGKDDKTSSKAFSEEDFLEMISASQMMENQYGHL---FEK 586

  Fly   199 IINNVDIDVAYEEFRNFVVQELKEQQKQ 226
            :|.|.|:.||:.|.:    |.||:.:.:
Zfish   587 VIVNDDLTVAFSELK----QALKKVETE 610

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11811	NP_648408.1	Guanylate_kin	34..219	CDD:279019	63/214 (29%)
CG11811	NP_648408.1	guanyl_kin	36..216	CDD:213788	63/211 (30%)
mpp7a	XP_021335692.1	L27	12..68	CDD:197794
		L27	74..125	CDD:197794
		PDZ_signaling	137..217	CDD:238492
		SH3	232..292	CDD:327375
		GuKc	403..608	CDD:214504	61/211 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910