DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11811 and SPBC1198.05

DIOPT Version :9

Sequence 1:	NP_648408.1	Gene:	CG11811 / 39213	FlyBaseID:	FBgn0036099	Length:	233	Species:	Drosophila melanogaster
Sequence 2:	NP_595074.1	Gene:	SPBC1198.05 / 2539674	PomBaseID:	SPBC1198.05	Length:	202	Species:	Schizosaccharomyces pombe

Alignment Length:	194	Identity:	88/194 - (45%)
Similarity:	133/194 - (68%)	Gaps:	5/194 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 SSSAAASLTSKKMTAPGPRPLVLCGPSGSGKSTLLKRLFAEFPSTFGFSISHTTRKPREGEEHGV 82
            |||.|:.|.:.|:     :|:|:.||||.|||||||||..:.....|||:|||||.||.||:.|:
pombe     6 SSSVASKLVTLKL-----KPVVVFGPSGVGKSTLLKRLLKDHGDKLGFSVSHTTRTPRAGEKDGI 65

  Fly    83 HYYFVERPEMEAAIAGDEFIETAEFTGNLYGTSKAAVREIQAQGRVCILDIEQKGVEQIKRTDLN 147
            .|:||.:.|.:..:|.::|:|.|.|:||:||||..|::|::|..:..||||:.:||.|:|.:.::
pombe    66 DYHFVTKEEFQKLVAEEKFVEWAVFSGNMYGTSIMAIQELEAVNKKAILDIDLQGVLQVKASPID 130

  Fly   148 PILIFNNPPSIKELERRLRKRGSETEESLSKRLNAAQVELDYGLTPGNFHKIINNVDIDVAYEE 211
            ...:|..||||::||.|||.||:|.|.::.:||..|:.|::|...||||..:|.|.|::.||::
pombe   131 AQYVFLAPPSIEQLEVRLRGRGTENESAILQRLERARAEIEYSEKPGNFDALIVNDDVEKAYKQ 194

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11811	NP_648408.1	Guanylate_kin	34..219	CDD:279019	82/178 (46%)
CG11811	NP_648408.1	guanyl_kin	36..216	CDD:213788	82/176 (47%)
SPBC1198.05	NP_595074.1	Gmk	17..201	CDD:223272	83/183 (45%)
SPBC1198.05	NP_595074.1	guanyl_kin	19..201	CDD:213788	82/176 (47%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	173	1.000	Domainoid score	I878
eggNOG	1	0.900	-	-		E1_COG0194
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H665
Inparanoid	1	1.050	177	1.000	Inparanoid score	I1149
OMA	1	1.010	-	-		QHG62608
OrthoFinder	1	1.000	-	-		FOG0002663
OrthoInspector	1	1.000	-	-		oto101239
orthoMCL	1	0.900	-	-		OOG6_100603
Panther	1	1.100	-	-	LDO	PTHR23117
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R636
SonicParanoid	1	1.000	-	-		X2036
TreeFam	1	0.960	-	-
	14	13.860