Protein Alignment CG11811 and guk-1

DIOPT Version :10

• Sequence 1: NP_648408.1
• Gene: CG11811 / 39213
• FlyBaseID: FBgn0036099
• Length: 233
• Species: Drosophila melanogaster
• Sequence 2: NP_491243.1
• Gene: guk-1 / 171963
• WormBaseID: WBGene00020190
• Length: 216
• Species: Caenorhabditis elegans
• Alignment Length: 759
• Identity: 152/759 - (20%)
• Similarity: 248/759 - (32%)
• Gaps: 222/759 - (29%)

  Fly   300 MKMEVESLGFGDHRQDHRQRRSPVRPSSPLMSPMSHMSQVSEFSLDNMQKFHKENDLLTERLLAM 364
            :|.|.|...:||:..|                       :|..|.|:.:....::|.|:.  |:.
 Worm    34 LKSEHEDSIWGDYTLD-----------------------LSFLSSDDQRSGLDDDDSLSN--LSR 73

  Fly   365 EEETKMLKEALAKRNSELQVSRNLCAKTANRLQTLEAQMMSKSPTKRGFEMPAEIFSRQNASNPP 429
            :.||.  ||.|                      .||.::.|..   :....|...||:.     |
 Worm    74 DVETN--KEGL----------------------VLEEKIASSG---KVLVNPNPSFSKL-----P 106

  Fly   430 SMASMSEDGNEDAR------SVAGSLMSELSQSNKDKA--------NAKIKKTESANQLELMDD- 479
            .:...|.|...||:      |...|..|:|.:|.:|..        .:....|:|.......||
 Worm   107 EVLMKSSDVVGDAKLGLSCVSEKSSTESDLDESEEDSPCWKGMLSHKSLASGTKSMTSRRSTDDL 171

  Fly   480 --FLEMEKLA--CLPNGSNANGSTDHSSADSDAEIPPATQLKKRISNVLQSLPKDAAFEKILAEI 540
              |.::..||  .:|:.|.....||....:..:    ::.|||.:|:...|  ....|:.....:
 Worm   172 SGFRKLNPLAPQFIPSSSKKKLETDGEKCEETS----SSSLKKSLSSTFPS--SSGEFDLTDPPL 230

  Fly   541 QCAVKDAGVKLPSKSHGAN--LNGLTEE---KVIAMSNETTEEKVTIVEVITQELSDALSQIYQF 600
            :....||..|....:|.|:  |..:|.:   |.::|.:...|.:       ..:..|.|:.:  |
 Worm   231 EDGRNDAAEKTSILTHNADEILGFVTSDSVSKTVSMLDSRNEFQ-------PSKRLDPLAPV--F 286

  Fly   601 VTYLSKEATACSENRTFSQKVQEFSTTFEGVLGKEKTLVDFLFDLSRVLVEASEL----KIDVLG 661
            |...:|...:..|      |:.:|............:.|..| |..:|:..:.|:    |....|
 Worm   287 VPSSAKLGPSVHE------KLGDFVVNAYSTSALASSHVKSL-DKGKVVTSSGEVGHSFKSQYGG 344

  Fly   662 FHTSTVEIHSPDCIDKVALPE-------NKALQK-------------DSSGEHYQNGCSQSSDSE 706
            ....:...:.|....:|.:.|       ||:..:             |:..:.|..|.:|::
 Worm   345 HDFGSTSSYGPWIESEVGITEYAKLGSSNKSQGQRRLNPLARQFSLADAKQKPYGYGKNQAA--- 406

  Fly   707 IPDDCN---GTSG-YEP------------KLATCKFTTEEF------EGLKLEKEKAESNLASCE 749
              ||.:   .||| |.|            .||......|.|      .|..|...||:||..|
 Worm   407 --DDLSLVVNTSGLYIPARYREDHNVVDADLAQSSVNVERFLPNMSHGGSSLITPKADSNFGS-- 467

  Fly   750 ADLEATKTKLQETEKLLAEVKSDLESAQKSNGMGETQLKCMVESYRSLETRSSELEIELTSLKGK 814
                         .|.:| |:.:...:.|.|...:..|     .:..:||.:|....::.:|.|.
 Worm   468 -------------TKWIA-VEPNPTFSVKGNRDFKHHL-----PFHVVETAASSSTSDMKALPGP 513

  Fly   815 IENLEDELHDEKENHREALAKCQELEEQLQRNNQNCPNCSVIEDDPKSKQDNELAAAAEKLAECQ 879
                     ..|.:.::.|.....|.|.|     ...:.|...|.|.          ||:|....
 Worm   514 ---------SPKMDVKKLLTTMHGLSELL-----TLAHGSESSDSPN----------AEELDLIN 554

  Fly   880 ETILLLGKQLKSMCPQTEQVASSPSQEQQALNPEEEEYATSTNPQDSKLSSPSDKDTPSMNTM-- 942
            .|:..|...:::   .:::.|.:.|..|.      ..|.....|..||||. .|...|:.|.|
 Worm   555 STVQNLNLYIQN---NSQEHAGNQSVAQY------NSYDLKLLPNKSKLSI-RDHQFPTANNMTV 609

  Fly   943 ------KSPVASKHRHTKSNSSSSSSGLTPEKHSRGFSR--FFS 978
                  |...:...|.|...|.|...|.|.:   .||.:  |||
 Worm   610 DLDVKRKDKYSVVSRETVPGSRSYQYGATED---NGFGQVCFFS 650

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11811	NP_648408.1	guanyl_kin	36..216	CDD:213788
guk-1	NP_491243.1	guanyl_kin	25..208	CDD:213788	45/234 (19%)