DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11811 and Card14

DIOPT Version :9

Sequence 1:	NP_648408.1	Gene:	CG11811 / 39213	FlyBaseID:	FBgn0036099	Length:	233	Species:	Drosophila melanogaster
Sequence 2:	XP_006532429.1	Gene:	Card14 / 170720	MGIID:	2386258	Length:	1029	Species:	Mus musculus

Alignment Length:	131	Identity:	31/131 - (23%)
Similarity:	55/131 - (41%)	Gaps:	15/131 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   100 EFIETAEFTGNLYGTSKAAVREIQAQGRVCILDIEQKGVEQIKRTDLNPILIF--NNPPSIKELE 162
            :.|:..|..|:.:..::.||..:.......:||:....|..:.|.|:.||:|.  .|..:.|:|.
Mouse   898 DIIQEGESIGDHHWITRHAVESLMNMSTHALLDVRLDSVRVLHRMDMFPIIIHVSVNEKTAKKLR 962

  Fly   163 RRLRKRGSETEESLSKRLNAAQVELD------YGLTPGNFHKIINNVDIDVAYEEFRNFVVQELK 221
            :.|.:.|| :||...:.....:.|||      ..|.|.::.      |:|......|..:..|.|
Mouse   963 KGLHRLGS-SEEQFLEVARQEEGELDRVPCLYSSLAPDSWS------DLDSLLSCVRLAIADEQK 1020

  Fly   222 E 222
            :
Mouse  1021 K 1021

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11811	NP_648408.1	Guanylate_kin	34..219	CDD:279019	29/126 (23%)
CG11811	NP_648408.1	guanyl_kin	36..216	CDD:213788	29/123 (24%)
Card14	XP_006532429.1	DD	19..104	CDD:387368
		Smc	<132..410	CDD:224117
		PDZ_signaling	587..659	CDD:238492
		SH3	684..745	CDD:388381
		NK	<884..1008	CDD:388413	28/116 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0194
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900