DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11811 and Patj

DIOPT Version :9

Sequence 1:	NP_648408.1	Gene:	CG11811 / 39213	FlyBaseID:	FBgn0036099	Length:	233	Species:	Drosophila melanogaster
Sequence 2:	XP_038965114.1	Gene:	Patj / 140581	RGDID:	1565362	Length:	1858	Species:	Rattus norvegicus

Alignment Length:	270	Identity:	58/270 - (21%)
Similarity:	96/270 - (35%)	Gaps:	104/270 - (38%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 SSSSSSAAASLTSKK---------MTAPGP--------RPLVLCGPSGSGKSTLLKRLFAEFPST 62
            ||..::||..|..::         .:..||        .|.|..|.|..|..|::|||
  Rat  1044 SSRHANAACELPEREEGEGEETPNFSHWGPPRIVEIFREPNVSLGISIVGGQTVIKRL------- 1101

  Fly    63 FGFSISHTTRKPREGEE-HGVHYYFVER-------PEMEAAIAGDEFIETAEFTGNLYGTSKA-A 118
                        :.||| .|:   |:::       .:.:|...||:.:|.:..  :|...|.| |
  Rat  1102 ------------KNGEELKGI---FIKQVLEDSPAGKTKALKTGDKILEVSGV--DLQNASHAEA 1149

  Fly   119 VREIQAQGRVCILDIEQKGVEQIKRTDLNPILI--FNN----PPSIKE---LERRLRKRG----- 169
            |..|::.|...:.     .|:.:..|   |.:|  .||    ||..::   .|::.::.|
  Rat  1150 VEAIKSAGNPVVF-----VVQSLSST---PRVIPSVNNKGKTPPQNQDQNTQEKKAKRHGTAPPP 1206

  Fly   170 -----------SETEES-LSKRLNAAQVELDYGLTPGNFHKIINNVDIDVAYEEFRNFVVQELKE 222
                       ::|||| ....|...::...|...||..|.|                   || |
  Rat  1207 MKLPPPYRAPSADTEESEEDSALTDKKIRQRYADLPGELHII-------------------EL-E 1251

  Fly   223 QQKQGVSVNL 232
            :.|.|:.::|
  Rat  1252 KDKNGLGLSL 1261

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11811	NP_648408.1	Guanylate_kin	34..219	CDD:279019	47/227 (21%)
CG11811	NP_648408.1	guanyl_kin	36..216	CDD:213788	45/214 (21%)
Patj	XP_038965114.1	L27_2	8..65	CDD:312549
		PDZ_signaling	135..218	CDD:238492
		PDZ_signaling	248..325	CDD:238492
		PDZ_signaling	366..450	CDD:238492
		CtpA	<391..>511	CDD:223864
		PDZ_signaling	572..636	CDD:238492
		PDZ	684..773	CDD:214570
		PDZ_signaling	1074..1165	CDD:238492	25/119 (21%)
		PDZ	1244..1329	CDD:214570	8/38 (21%)
		PDZ	1471..1578	CDD:214570
		PDZ_signaling	1590..1670	CDD:238492
		PDZ_signaling	1731..1816	CDD:238492
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0194
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900