DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11811 and dlg5b.1

DIOPT Version :9

Sequence 1:	NP_648408.1	Gene:	CG11811 / 39213	FlyBaseID:	FBgn0036099	Length:	233	Species:	Drosophila melanogaster
Sequence 2:	XP_021336124.1	Gene:	dlg5b.1 / 101883945	ZFINID:	ZDB-GENE-120206-4	Length:	1907	Species:	Danio rerio

Alignment Length:	165	Identity:	38/165 - (23%)
Similarity:	72/165 - (43%)	Gaps:	21/165 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 KMTAPGPRPLVLCGPSGSGKSTLLKRLFAEFPSTFGFSISHTTRKPREGEEHGVHYYFVERPEME 93
            |:.:...||:::.||.......:|.|   |.|..:...:....:..::..|.||....
Zfish  1721 KVESTNRRPVLILGPLVEPIKDMLLR---EAPGKYCRCLPEGMKAQQQAIERGVKDCL------- 1775

  Fly    94 AAIAGDEFIETAEFTGNLYGTSKAAVREIQAQGRVCILDIEQKGVEQIKRTDLNPILIF---NNP 155
                   ||:....:|:...|:.|:::||..:...|:|||....:|::....:.||:||   .|.
Zfish  1776 -------FIDYKRRSGHFDVTTVASIKEITEKDCHCLLDIAPHAIERLHAVSIYPIVIFIRYRNA 1833

  Fly   156 PSIKELERRLRKRGSETEESLSKRLNAAQ-VELDY 189
            ..|||.:..:..|...:::...::..:|| :|.||
Zfish  1834 KQIKEQKDPVYLRDKVSQKHSKEQFESAQRIEQDY 1868

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11811	NP_648408.1	Guanylate_kin	34..219	CDD:279019	37/160 (23%)
CG11811	NP_648408.1	guanyl_kin	36..216	CDD:213788	37/158 (23%)
dlg5b.1	XP_021336124.1	Takusan	120..209	CDD:309799
		APG6	232..>311	CDD:309295
		SMC_N	<287..661	CDD:330553
		PDZ_signaling	686..774	CDD:238492
		PDZ_signaling	<797..857	CDD:238492
		PDZ	1345..1426	CDD:214570
		dbPDZ_assoc	1425..1486	CDD:318751
		PDZ	1491..1567	CDD:214570
		SH3_DLG5	1585..1647	CDD:212794
		NK	1740..1896	CDD:327404	33/146 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0194
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810