DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG11811 and dlg4

DIOPT Version :9

Sequence 1:	NP_648408.1	Gene:	CG11811 / 39213	FlyBaseID:	FBgn0036099	Length:	233	Species:	Drosophila melanogaster
Sequence 2:	XP_009300293.1	Gene:	dlg4 / 100000823	-ID:	-	Length:	805	Species:	Danio rerio

Alignment Length:	180	Identity:	64/180 - (35%)
Similarity:	96/180 - (53%)	Gaps:	25/180 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 RPLVLCGPSGSGKSTLLKRLFAEFPSTFGFSISHTTRKPREGEEHGVHYYFV-ERPEMEAAIAGD 99
            ||:::.||.   |..:...|.:|||..||..:.||||..||.|..|..|:|| .|.:||..|...
Zfish   615 RPIIILGPV---KDRVNDDLLSEFPDKFGSCVPHTTRPKREYEVDGRDYHFVSSREQMEKDIQNH 676

  Fly   100 EFIETAEFTGNLYGTSKAAVREI-QAQGRVCILDIEQKGVEQIKRTDLNPILIFNNPPSIK---E 160
            .|||..::..:|||||..:|||: :.||:.||||:....|.:::...|:||.||..|.|::   |
Zfish   677 RFIEAGQYNSHLYGTSVQSVREVAEQQGKHCILDVSANAVRRLQAAQLHPIAIFVRPKSLENVLE 741

  Fly   161 LERRLRKRGSETEESLSKRLN-AAQVELDY-----GLTPGN-----FHKI 199
            :..||      |||...|.:: |.::|.|:     .:..|:     :||:
Zfish   742 INTRL------TEEQARKGMDRAIKLEQDFLECFSAIVEGDSFEEVYHKV 785

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11811	NP_648408.1	Guanylate_kin	34..219	CDD:279019	64/180 (36%)
CG11811	NP_648408.1	guanyl_kin	36..216	CDD:213788	64/180 (36%)
dlg4	XP_009300293.1	MAGUK_N_PEST	39..141	CDD:287565
		PDZ_signaling	142..226	CDD:238492
		PDZ	234..323	CDD:214570
		PDZ_assoc	334..389	CDD:287558
		DegQ	<372..465	CDD:223343
		PDZ	388..471	CDD:214570
		SH3	507..572	CDD:302595
		Guanylate_kin	613..792	CDD:279019	64/180 (36%)
		GuKc	624..792	CDD:214504	60/168 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0194
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810