Protein Alignment simj and GATAD2B

DIOPT Version :10

• Sequence 1: NP_001261685.1
• Gene: simj / 39212
• FlyBaseID: FBgn0010762
• Length: 937
• Species: Drosophila melanogaster
• Sequence 2: XP_047282071.1
• Gene: GATAD2B / 57459
• HGNCID: 30778
• Length: 594
• Species: Homo sapiens
• Alignment Length: 692
• Identity: 210/692 - (30%)
• Similarity: 292/692 - (42%)
• Gaps: 198/692 - (28%)

  Fly    31 AALSNRDLRALTANNAGLTITPSASPATNNGTTSNSSNTNSNSSSTTTTTNNNNNSSSNTNSSSA 95
            |.|..:||       |.|.: |...|...:|:.........|.       |...:..:.|.....
Human    48 ALLKRKDL-------ANLEV-PHELPTKQDGSGVKGYEEKLNG-------NLRPHGDNRTAGRPG 97

  Fly    96 NNNNNNNSINASDGVTGATSGSIGGGQDENKVQRRVLRPRTEPK--SYAEAPDIVLLPARTNGRQ 158
            ..|.|:..::.|                         ..|:||:  ....:|||::|.
Human    98 KENINDEPVDMS-------------------------ARRSEPERGRLTPSPDIIVLS------- 130

  Fly   159 QNGNIDSETDD-------EEMPPYVPIKELSHAELKEREKSLRKLRQDLRNEETKLMLLKKLKQS 216
                 |:|...       ||......::......::||::.:::||.:||.||.:|:|||||:||
Human   131 -----DNEASSPRSSSRMEERLKAANLEMFKGKGIEERQQLIKQLRDELRLEEARLVLLKKLRQS 190

  Fly   217 QQVMKENLVVTPTSVSPNNPLSAIPAALTSKGSLSVTPTSAVPLPAH-SKGSRSSLSGSGGPAVS 280
             |:.||| ||..|.|..|              :.|:..    |.||| .:...|.|....| |..
Human   191 -QLQKEN-VVQKTPVVQN--------------AASIVQ----PSPAHVGQQGLSKLPSRPG-AQG 234

  Fly   281 ISATNSRTGSSSSAAAAASAIAAAAMSGQHRSGSNSILPPPRSSLPAGATLAAGTTITPATSSSH 345
            :...|.||....|..               ||.:|:.||   ..|.:...:|.    .||.....
Human   235 VEPQNLRTLQGHSVI---------------RSATNTTLP---HMLMSQRVIAP----NPAQLQGQ 277

  Fly   346 RSSNLPP-----RTNLPNLTITPSVTITPTSAPPSSLKPRNVP--GTISNSVSITPALPLSQSHQ 403
            |.   ||     ||..||:  .|::...|.|:       .:||  .|.|:::.:..|     ||.
Human   278 RG---PPKPGLVRTTTPNM--NPAINYQPQSS-------SSVPCQRTTSSAIYMNLA-----SHI 325

  Fly   404 NQHNDQKNDRSTPREDAQT-PAQRQAAAKMALRKQLEKTLLQIPPPKPPPPEMHFIPNPSNTDFV 467
            ......:.....|...|.| .|..|||||:|||||||||||:|||||||.|.:||:|:.:|::|:
Human   326 QPGTVNRVSSPLPSPSAMTDAANSQAAAKLALRKQLEKTLLEIPPPKPPAPLLHFLPSAANSEFI 390

  Fly   468 YLLGLETVVDYLTVNKKANAVAA-----PFRCAQCKIDFTPVWKWEKQTNKDPKVICEQCVTSNV 527
            |::|||.||..: ::.:..:.|:     ||.||||:.||||.||.|    |:.|::||||:|||.
Human   391 YMVGLEEVVQSV-IDSQGKSCASLLRVEPFVCAQCRTDFTPHWKQE----KNGKILCEQCMTSNQ 450

  Fly   528 KKALKAEHTNRLKQAFVKALQQEQEIEQRLASQSSPSPVDNHGSSGGGNSLSVSAVSSNSSSSHM 592
            |||||||||||||.||||||||||||||||..|::.||.            :..||||.|
Human   451 KKALKAEHTNRLKNAFVKALQQEQEIEQRLQQQAALSPT------------TAPAVSSVS----- 498

  Fly   593 QREREQLQASHASAAAALVNLPPSVTVIPTKCQTPTPATPRPTPPPPQSQATPPPSSGGSRSSRA 657
              ::|.:...|                           |.|..|.|..|.....|:|..|..|
Human   499 --KQETIMRHH---------------------------TLRQAPQPQSSLQRGIPTSARSMLS-- 532

  Fly   658 AATAAAAAIAAQQAGILS-PGPSPAH-------HHEPTTSSR 691
              ..|.|...:...|:|. ||.:.|:       |..|:.:.|
Human   533 --NFAQAPQLSVPGGLLGMPGVNIAYLNTGIGGHKGPSLADR 572

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
simj	NP_001261685.1	P66_CC	185..225	CDD:465178	20/39 (51%)
GATAD2B	XP_047282071.1	P66_CC	160..198	CDD:465178	20/39 (51%)
		GATA	421..455	CDD:425605	23/37 (62%)