Protein Alignment simj and Gatad2b

DIOPT Version :9

• Sequence 1: NP_001261685.1
• Gene: simj / 39212
• FlyBaseID: FBgn0010762
• Length: 937
• Species: Drosophila melanogaster
• Sequence 2: XP_006501422.3
• Gene: Gatad2b / 229542
• MGIID: 2443225
• Length: 671
• Species: Mus musculus
• Alignment Length: 699
• Identity: 213/699 - (30%)
• Similarity: 291/699 - (41%)
• Gaps: 211/699 - (30%)

  Fly    31 AALSNRDLRALTANNAGLTITPSASPATNNGTTSNSSNTNSNSSSTTTTTNNNNNSSSNTNSSSA 95
            |.|..:||       |.|.: |...|...:|:.........|.:......||      .|.....
Mouse   124 ALLKRKDL-------ANLEV-PHELPTKQDGSGVKGYEEKLNGNLRPHGDNN------RTAGRPG 174

  Fly    96 NNNNNNNSINASDGVTGATSGSIGGGQDENKVQRRVLRPRTEPK--SYAEAPDIVLL------PA 152
            ..|.|:..::.|                         ..|:||.  ....:|||::|      ..
Mouse   175 KENINDEPVDMS-------------------------ARRSEPDRGRLTPSPDIIVLSDNEASSP 214

  Fly   153 RTNGRQQNGNIDSETDDEEMPPYVPIKELSHAELKEREKSLRKLRQDLRNEETKLMLLKKLKQSQ 217
            |::.|.           ||......::......::||::.:::||.:||.||.:|:|||||:||
Mouse   215 RSSSRM-----------EERLKAANLEMFKGKGMEERQQLIKQLRDELRLEEARLVLLKKLRQS- 267

  Fly   218 QVMKENLVVTPTSVSPNNPLSAIPAALTSKGSLSVTPTSAVPLPAH-SKGSRSSLSGSGGPAVSI 281
            |:.||| ||..|.|..|              :.|:..    |.||| .:...|.|....| |..|
Mouse   268 QLQKEN-VVQKTPVVQN--------------AASIVQ----PSPAHVGQQGLSKLPSRPG-AQGI 312

  Fly   282 SATNSRTGSSSSAAAAASAIAAAAMSGQHRSGSNSILPPPRSSLPAGATLAAGTTITPATSSSHR 346
            ...|.||....|..               ||.:|:.||   ..|.:...:|.    .||.....|
Mouse   313 EPQNMRTLQGHSVI---------------RSATNTTLP---HMLMSQRVIAP----NPAQLQGQR 355

  Fly   347 SSNLPP-----RTNLPNLTITPSVTITP------------TSAPPSSLKPRNVPGTISNSVSITP 394
            .   ||     ||..||:  .|:::..|            :||...:|.....|||::...|..|
Mouse   356 G---PPKPGIVRTTTPNM--NPAISYQPQSSSSVPCQRTTSSAIYMNLASHIQPGTVNRVSSPLP 415

  Fly   395 ALPLSQSHQNQHNDQKNDRSTPREDAQTPAQRQAAAKMALRKQLEKTLLQIPPPKPPPPEMHFIP 459
            : |.:.|                 ||   |..|||||:|||||||||||:|||||||.|.:||:|
Mouse   416 S-PSAMS-----------------DA---ANSQAAAKLALRKQLEKTLLEIPPPKPPAPLLHFLP 459

  Fly   460 NPSNTDFVYLLGLETVVDYLTVNKKANAVA----APFRCAQCKIDFTPVWKWEKQTNKDPKVICE 520
            :.:|::|:|::|||.||..:..::..|..:    .||.||||:.||||.||.|    |:.|::||
Mouse   460 SAANSEFIYMVGLEEVVQSVIDSQGKNCASLLRVEPFVCAQCRTDFTPHWKQE----KNGKILCE 520

  Fly   521 QCVTSNVKKALKAEHTNRLKQAFVKALQQEQEIEQRLASQSSPSPVDNHGSSGGGNSLSVSAVSS 585
            ||:|||.|||||||||||||.||||||||||||||||..|::.||.            :..||||
Mouse   521 QCMTSNQKKALKAEHTNRLKNAFVKALQQEQEIEQRLQQQAALSPT------------TAPAVSS 573

  Fly   586 NSSSSHMQREREQLQASHASAAAALVNLPPSVTVIPTKCQTPTPATPRPTPPPPQSQATPPPSSG 650
            .|       ::|.:...|                           |.|..|.|..|.....|:|.
Mouse   574 VS-------KQETIMRHH---------------------------TLRQAPQPQSSLQRGIPTSA 604

  Fly   651 GSRSSRAAATAAAAAIAAQQAGILS-PGPSPAH-------HHEPTTSSR 691
            .|..|    ..|.|...:...|:|. ||.:.|:       |..|:.:.|
Mouse   605 RSMLS----NFAQAPQLSVPGGLLGMPGVNIAYLNTGIGGHKAPSLADR 649

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
simj	NP_001261685.1	P66_CC	185..222	CDD:293171	17/36 (47%)
Gatad2b	XP_006501422.3	P66_CC	238..272	CDD:374633	17/34 (50%)
		GATA	498..531	CDD:366024	22/36 (61%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167838132
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	245	1.000	Inparanoid score	I3266
Isobase	1	0.950	-	0	Normalized mean entropy	S7145
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003555
OrthoInspector	1	1.000	-	-		otm42524
orthoMCL	1	0.900	-	-		OOG6_111121
Panther	1	1.100	-	-	O	PTHR13455
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R9898
SonicParanoid	1	1.000	-	-		X2908
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	12	11.870