Protein Alignment CG8003 and ANKMY2

DIOPT Version :10

• Sequence 1: NP_648406.1
• Gene: CG8003 / 39210
• FlyBaseID: FBgn0036096
• Length: 407
• Species: Drosophila melanogaster
• Sequence 2: NP_064715.1
• Gene: ANKMY2 / 57037
• HGNCID: 25370
• Length: 441
• Species: Homo sapiens
• Alignment Length: 402
• Identity: 157/402 - (39%)
• Similarity: 215/402 - (53%)
• Gaps: 41/402 - (10%)

  Fly    10 QLDDVQRQLLDHLAKNDTSGFKQLLS--GVRNVNFVDDTGMSCLAHASFKGNREAVQLLLDMGAD 72
            :|...:::||:.:.|........|||  .|| ||.:|:.||:.|.||::||..:..:|||..|||
Human     8 ELTQEEKELLEVIGKGTVQEAGTLLSSKNVR-VNCLDENGMTPLMHAAYKGKLDMCKLLLRHGAD 71

  Fly    73 INLNQHGADYTPLHFAALSGNTHVCRLLLDAGIKPGSINSVNRTAAQMAAFVGNHACVETINNYV 137
            :|.:||...||.|.|||||||..:..::|:||.:...:|||.|||||||||||.|.||..|||:.
Human    72 VNCHQHEHGYTALMFAALSGNKDITWVMLEAGAETDVVNSVGRTAAQMAAFVGQHDCVTIINNFF 136

  Fly   138 TQSSLEYYTQVHGQQTEPHIPPSLLKSFHAFVTEINLHPVRIALNVQSLGLLRILSSLRK---TL 199
            .:..|:|||:..|...||.:||.|....|..:|..|||||:|.:.|....||...::|.|   .:
Human   137 PRERLDYYTKPQGLDKEPKLPPKLAGPLHKIITTTNLHPVKIVMLVNENPLLTEEAALNKCYRVM 201

  Fly   200 ALMCEKEMQKSHDLNELLAFKFHYQGWILAELIRCEEQFKAQHKEKSGEEAGDANKNDFIEMFVK 264
            .|:|||.| |..|:||:||.|.||        |.|..| |..:..|.||     ||   ::..:|
Human   202 DLICEKCM-KQRDMNEVLAMKMHY--------ISCIFQ-KCINFLKDGE-----NK---LDTLIK 248

  Fly   265 RVLKENKLGQLD-----YVEYTLRECAREFPVRECTIFRQIATQFGAKDA---PPALTVLRNAIN 321
            .:||    |:..     |.|..:||..|:||..|.|:.:|:.......:.   |.|.:||..||.
Human   249 SLLK----GRASDGFPVYQEKIIRESIRKFPYCEATLLQQLVRSIAPVEIGSDPTAFSVLTQAIT 309

  Fly   322 GMRWITDEGNYCSTCGAEKPDKKCSKCKAVQYCDRECQRLHWFMHKKNCARLL----AQSQAQAQ 382
            |.....|. .:|:|||.:...|:||.||.|.|||:.||:.|||.|||.|..|.    .|....|:
Human   310 GQVGFVDV-EFCTTCGEKGASKRCSVCKMVIYCDQTCQKTHWFTHKKICKNLKDIYEKQQLEAAK 373

  Fly   383 AQPQSQAKGAID 394
            .:.|.:..|.:|
Human   374 EKRQEENHGKLD 385

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8003	NP_648406.1	ANKYR	<18..>131	CDD:440430	56/114 (49%)
		ANK repeat	46..76	CDD:293786	14/29 (48%)
		ANK repeat	78..105	CDD:293786	13/26 (50%)
		zf-MYND	333..370	CDD:460312	21/36 (58%)
ANKMY2	NP_064715.1	ANK repeat	16..43	CDD:293786	10/27 (37%)
		PHA03100	<30..>236	CDD:476869	98/216 (45%)
		ANKYR	<31..132	CDD:440430	54/101 (53%)
		ANK repeat	45..77	CDD:293786	14/31 (45%)
		ANK 1	45..74		13/28 (46%)
		ANK repeat	79..110	CDD:293786	13/30 (43%)
		ANK 2	79..108		13/28 (46%)
		ANK 3	159..188		10/28 (36%)
		zf-MYND	320..357	CDD:460312	21/36 (58%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	374..441		3/12 (25%)