DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32066 and fam49ba

DIOPT Version :9

Sequence 1:	NP_729619.1	Gene:	CG32066 / 39206	FlyBaseID:	FBgn0052066	Length:	324	Species:	Drosophila melanogaster
Sequence 2:	NP_956364.2	Gene:	fam49ba / 337591	ZFINID:	ZDB-GENE-030131-9537	Length:	325	Species:	Danio rerio

Alignment Length:	329	Identity:	183/329 - (55%)
Similarity:	238/329 - (72%)	Gaps:	9/329 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MGKLLSLLSRDDSNCCAAKSYDVFLDFENAAPTETERAVYDEVERVLRESEVVLDEIQIYRGAGK 65
            ||.|:.:|:||..|    .:.:.|||||||.|||.||.|::||..||||:.::|.::|.|.|||:
Zfish     1 MGNLIKVLTRDIDN----NAGNFFLDFENAKPTEAERRVWEEVNGVLREAAIILQDLQSYSGAGE 61

  Fly    66 EIREAIADPSPE-VTAKAWAAVLPLVNKLKRCYEHSMELDKIVPKLLGQLVGGKLNPTQHLETQQ 129
            .||:||..||.| |..:|||||:|||.|||:.||.|::|:..:..||..|...:.:||||||.:|
Zfish    62 AIRQAIQHPSDERVQEQAWAAVVPLVGKLKKFYEFSLKLEDTLQNLLEYLTSSRCSPTQHLEQEQ 126

  Fly   130 ALVKQLAEILEFVLKFDEYKMKTPAIQNDFSYYRRIVSRQRV---DSTENMLVSTELANRMSLFY 191
            ||.:|.||||.|.|:|||.||..||||||||||||.:||.|:   .:.|:..|..||||||||||
Zfish   127 ALARQFAEILHFTLRFDELKMTNPAIQNDFSYYRRTLSRMRIINQTAEEHNEVDNELANRMSLFY 191

  Fly   192 AHATPMLKVLSEATSKFVNDNAD-DVQNTTETLGTMAKVCLRMLENPKLLQQIEREDTKMLVLRV 255
            |:||||||.||:||:|||:.:|: .|:|||:.|.|||.||..|||.|:...:...|||.:..|||
Zfish   192 ANATPMLKTLSDATTKFVSKHAELPVENTTDCLSTMASVCKVMLETPEYRSRFASEDTVLFCLRV 256

  Fly   256 MVGLVILYDHVHPEGAFVRGAHVDVKGCVRLLQAQPAIKAEPLLNALRYTTKHLNGENTPKNIQR 320
            |||::||||:|||.||||:.:.:|:|||:::|:.|||...|.|||||||||||||.|:|.|.|:.
Zfish   257 MVGVIILYDYVHPAGAFVKSSKIDMKGCIKVLRYQPANSVEGLLNALRYTTKHLNDESTSKQIKN 321

  Fly   321 LLAA 324
            :|.|
Zfish   322 MLQA 325

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32066	NP_729619.1	DUF1394	22..319	CDD:399855	173/301 (57%)
fam49ba	NP_956364.2	DUF1394	18..320	CDD:284554	173/301 (57%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170592593
Domainoid	1	1.000	336	1.000	Domainoid score	I1083
eggNOG	1	0.900	-	-		E1_KOG3951
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H102168
Inparanoid	1	1.050	347	1.000	Inparanoid score	I2270
OMA	1	1.010	-	-		QHG54626
OrthoDB	1	1.010	-	-		D1129868at2759
OrthoFinder	1	1.000	-	-		FOG0002340
OrthoInspector	1	1.000	-	-		otm25135
orthoMCL	1	0.900	-	-		OOG6_103389
Panther	1	1.100	-	-	O	PTHR12422
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5116
SonicParanoid	1	1.000	-	-		X1542
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	16	15.800