DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment E(z) and CG4565

DIOPT Version :9

Sequence 1:	NP_001261682.1	Gene:	E(z) / 39203	FlyBaseID:	FBgn0000629	Length:	765	Species:	Drosophila melanogaster
Sequence 2:	NP_001097743.1	Gene:	CG4565 / 41303	FlyBaseID:	FBgn0037841	Length:	269	Species:	Drosophila melanogaster

Alignment Length:	210	Identity:	66/210 - (31%)
Similarity:	96/210 - (45%)	Gaps:	44/210 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   580 CRCKAQC-NTKQCP-----------CYLAVR-------ECDPDLCQACGADQFKLTKITCKNVCV 625
            |.||..| |::.|.           ..|.:|       ||: |:|:.|        :.||.|..|
  Fly    50 CHCKGACENSEVCAHGGQYEFTEDGSELILRNSANPVIECN-DMCKCC--------RNTCSNRLV 105

  Fly   626 QRGLHKHLLMAPSDIAG-WGIFLKEGAQKNEFISEYCGEIISQDEADRRGKVYDKY---MCSFLF 686
            ..|..|||.:..|.:.| .|:.......|..:|.||.||:::..||  |.:::|..   :.:::.
  Fly   106 YSGPRKHLEIFDSPVYGSKGLRTTAKITKGGYICEYAGELLTVPEA--RSRLHDNEKLGLMNYIL 168

  Fly   687 NLN---ND-----FVVDATRKGNKIRFANHSINPNCY-AKVMMVTGDHRIGIFAKRAIQPGEELF 742
            .||   :|     .:||.:|:||..|:.|||..|||: |.|.:.....:|||||.|.|...|||.
  Fly   169 VLNEYTSDKKQQVTIVDPSRRGNIGRYLNHSCEPNCHIAAVRIDCPIPKIGIFAARDIAAKEELC 233

  Fly   743 FDYRYGPTEQLKFVG 757
            |.|. |..:..|..|
  Fly   234 FHYG-GEGQYKKMTG 247

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
E(z)	NP_001261682.1	SANT	452..492	CDD:238096
		SET	<471..745	CDD:225491	62/196 (32%)
		SET	631..747	CDD:214614	45/128 (35%)
CG4565	NP_001097743.1	Pre-SET	10..103	CDD:282838	15/61 (25%)
CG4565	NP_001097743.1	SET	111..239	CDD:214614	45/130 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.910