Protein Alignment E(z) and ash1

DIOPT Version :9

• Sequence 1: NP_001261682.1
• Gene: E(z) / 39203
• FlyBaseID: FBgn0000629
• Length: 765
• Species: Drosophila melanogaster
• Sequence 2: NP_001246834.1
• Gene: ash1 / 40133
• FlyBaseID: FBgn0005386
• Length: 2226
• Species: Drosophila melanogaster
• Alignment Length: 627
• Identity: 140/627 - (22%)
• Similarity: 223/627 - (35%)
• Gaps: 178/627 - (28%)

  Fly   193 ETLAKSKQGEDDGVVDVDADGESPMKLEKTDSKGDLTEVEKKETEE------------------P 239
            |.|...::......|:|.|....|:..|:....|:..|.....|.:                  |
  Fly   998 EPLQSLRETRSSNNVNVQAAPNPPLDCERVPQAGEARETFVARTNQKAPRLSVVALERLQRPQTP 1062

  Fly   240 LETEDADVKPDVEEVKDKLPFPAPIIFQAISANFPDKGTAQELKEKYIELTEHQDP--ERPQECT 302
            ........||...|..:..|.|.|.....|.   |.|...::.|:..:|......|  ::..:..
  Fly  1063 ARGRPRGRKPKNREQAEAAPQPPPKSEPEIR---PAKKRGRQPKQPVLEEPPPTPPPQQKKNKME 1124

  Fly   303 PNI---DGIKAESVSRERTMHSFHTLFCRRCFKYDCFLHRHHVQGLQGHAGPNLQKRRYP----E 360
            |||   |||...:                   .:.|.:.....:.|:....|..:|...|    |
  Fly  1125 PNIRLPDGIDPNT-------------------NFSCKIRLKRRKNLEAGTQPKKEKPVQPVTVEE 1170

  Fly   361 LKPFAEPCSNSCYMLIDGMKEKLAADSKTPPIDSCNE-----ASSEDSNDSNSQFSNKDFNHENS 420
            :.| ..|.|          :|::.|:::...:||...     .:||..|.....:::..   |:|
  Fly  1171 IPP-EIPVS----------QEEIDAEAEAKRLDSIPTEHDPLPASESHNPGPQDYASCS---ESS 1221

  Fly   421 KDNGLTVNSAAVAEINS--IMAGMMNITSTQCVWTGADQALYRVLHKVYLK-------------- 469
            :|...|.:...::::..  ::||:.:        ....|:|.....||..|
  Fly  1222 EDKASTTSLRKLSKVKKTYLVAGLFS--------NHYKQSLMPPPAKVNKKPGLEEQVGPASLLP 1278

  Fly   470 --NYCAIAHNMLTKTCRQVYEFAQKEDAEFSFE---DLRQDFTPPRKKKKKQRLWSLHCRKIQLK 529
              .||   ...|.:|             |..||   |:...:| ..|...:..:.|.:.|||:
  Fly  1279 PPPYC---EKYLRRT-------------EMDFELPYDIWWAYT-NSKLPTRNVVPSWNYRKIR-- 1324

  Fly   530 KDSSSNHVY------NYTPCDHPGHPCDMNCSCIQTQNFCEKFCNCSSDCQNRFPGCRCKAQCNT 588
                 .:||      |....|||      .|:|   :|..||  :|..:|.||
  Fly  1325 -----TNVYAESVRPNLAGFDHP------TCNC---KNQGEK--SCLDNCLNR------------ 1361

  Fly   589 KQCPCYLAVRECDPDLCQACGADQFKLTKITCKNVCVQR-----GLHKHLLMAPSDIAGWGIFLK 648
                  :...||.|..|.| |.        .|:|..:||     |:.:.:   .:| .|||:..|
  Fly  1362 ------MVYTECSPSNCPA-GE--------KCRNQKIQRHAVAPGVERFM---TAD-KGWGVRTK 1407

  Fly   649 EGAQKNEFISEYCGEIISQDE-ADRRGKVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSINP 712
            ....|..:|.||.||::::.| ..|...:|......:..:|:...|:|..|.|:..||.|||..|
  Fly  1408 LPIAKGTYILEYVGEVVTEKEFKQRMASIYLNDTHHYCLHLDGGLVIDGQRMGSDCRFVNHSCEP 1472

  Fly   713 NCYAKVMMVTGDHRIGIFAKRAIQPGEELFFDYR---YGPTE 751
            ||..:...|.|..|:.:||||||:.||||.:||.   :.|:|
  Fly  1473 NCEMQKWSVNGLSRMVLFAKRAIEEGEELTYDYNFSLFNPSE 1514

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E(z)	NP_001261682.1	SANT	452..492	CDD:238096	9/55 (16%)
		SET	<471..745	CDD:225491	80/288 (28%)
		SET	631..747	CDD:214614	42/119 (35%)
ash1	NP_001246834.1	AWS	1340..1388	CDD:197795	22/85 (26%)
		SET	1392..1512	CDD:214614	42/123 (34%)
		Bromo_ASH1	1680..1787	CDD:99955
		PHD_ASH1L	1858..1900	CDD:277023
		BAH_polybromo	1929..2073	CDD:240068

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.910