Protein Alignment hay and xpb-1

DIOPT Version :9

• Sequence 1: NP_001137931.1
• Gene: hay / 39202
• FlyBaseID: FBgn0001179
• Length: 798
• Species: Drosophila melanogaster
• Sequence 2: NP_499487.1
• Gene: xpb-1 / 176584
• WormBaseID: WBGene00013441
• Length: 789
• Species: Caenorhabditis elegans
• Alignment Length: 810
• Identity: 502/810 - (61%)
• Similarity: 612/810 - (75%)
• Gaps: 43/810 - (5%)

  Fly     6 KSRKDRSGGDKFGKKRRAEDEAFTQLVDDNDSLDATESEGIPGAASKNAE-TNDEQINTDEYGAK 69
            |.||.|...|.:    :||:.  ..|...|..   .|:..:|.|||.|.. .|...:.|||:|||
 Worm     4 KERKRRGKWDTY----KAEEA--PSLYSGNAD---KETSSVPKAASHNLNGENASSVMTDEFGAK 59

  Fly    70 DYRSQMQLRPDHGNRPLWVAPNGHVFLESFSPVYKHAHDFLIAISEPVCRPEHIHEYKLTAYSLY 134
            |||..|.|:.|...|||||||:||:||||||||||||.|||||||||||||:|||||:|||||||
 Worm    60 DYRKDMPLKGDFTARPLWVAPDGHIFLESFSPVYKHARDFLIAISEPVCRPQHIHEYQLTAYSLY 124

  Fly   135 AAVSVGLQTHDIVEYLKRLSKTSIPEGILEFIRLCTLSYGKVKLVLKHNKYFIESPHPEVLQKLL 199
            |||||||||.||:|||:||||:.:|:|::.|:::||:||||||||||||:||:||.|.:|:||||
 Worm   125 AAVSVGLQTKDIIEYLERLSKSQLPKGVITFVQMCTVSYGKVKLVLKHNRYFVESRHSDVMQKLL 189

  Fly   200 KDPVIQKCRLIRSEGEDFIQGTLDGKAITQFGTKLPPG-------ATDKPTPDPAAAAGADGTTA 257
            ||.|||.|.|     :|.:|.....:...|...|...|       ..|....|..|||..||  .
 Worm   190 KDSVIQSCIL-----DDRVQPAQQTELPAQEKIKFSHGNENEKGVEKDGAAADGTAAAATDG--K 247

  Fly   258 VPEDITDFYEKID-KEEEDEDEANLKTVSFEVAQEKIEVIQKRCIEIEHPLLAEYDFRNDTNNPD 321
            ||.||.:||.||| .:|||.:..||:.::||:.||.||.:||||||:|:||||||||||||.||:
 Worm   248 VPADIDEFYGKIDGDDEEDAEIRNLQLLTFEIKQETIETVQKRCIELEYPLLAEYDFRNDTLNPN 312

  Fly   322 INIDLKPAAVLRPYQEKSLRKMFGNGRARSGVIVLPCGAGKSLVGVTACCTVRKRALVLCNSGVS 386
            :.|||||:..|||||||||||||||.|||||||||||||||:||||||..||.||.|||.||.||
 Worm   313 LGIDLKPSTTLRPYQEKSLRKMFGNSRARSGVIVLPCGAGKTLVGVTAVTTVNKRCLVLANSNVS 377

  Fly   387 VEQWKQQFKMWSTADDSMICRFTSEAKD---------KPMGCGILVTTYSMITHTQKRSWEAEQT 442
            ||||:.|||:|||..|..:.|||.||||         ||:.|   ::||||:.::.:|:.:||:.
 Worm   378 VEQWRAQFKLWSTIQDKQLVRFTREAKDPAPSGADATKPVVC---ISTYSMVAYSGRRTLQAEEA 439

  Fly   443 MRWLQEQEWGIMVLDEVHTIPAKMFRRVLTIVQSHCKLGLTATLLREDDKIADLNFLIGPKLYEA 507
            |:::::||||:::||||||||||||||||||||:||||||||||:||||||.|||||||||:|||
 Worm   440 MKFIEKQEWGLLLLDEVHTIPAKMFRRVLTIVQAHCKLGLTATLVREDDKITDLNFLIGPKIYEA 504

  Fly   508 NWLELQKKGYIARVQCAEVWCPMSPEFYREYLTTKTSKKMLLYVMNPSKFRSCQFLIKYHEQRGD 572
            ||:||||.|:||:||||||||||:..||..||.::.::|:||.||||:|||.||||||:||:|.|
 Worm   505 NWMELQKAGHIAKVQCAEVWCPMTSAFYSYYLRSQIARKLLLAVMNPNKFRICQFLIKFHERRND 569

  Fly   573 KTIVFSDNVFALKHYAIKMNKPFIYGPTSQNERIQILQNFKFNSKVNTIFVSKVADTSFDLPEAN 637
            |.|||||||||||.|||:|.|||:||.||||||::|||||::|.:||||||||||||||||||||
 Worm   570 KIIVFSDNVFALKRYAIEMQKPFLYGETSQNERMKILQNFQYNPRVNTIFVSKVADTSFDLPEAN 634

  Fly   638 VLIQISSHGGSRRQEAQRLGRILRAKKGAIAEEYNAFFYTLVSQDTMEMSYSRKRQRFLVNQGYS 702
            ||||||:||||||||||||||||||||.: .:::|||||:||||||:||.||||||||||||||:
 Worm   635 VLIQISAHGGSRRQEAQRLGRILRAKKHS-TDQFNAFFYSLVSQDTVEMGYSRKRQRFLVNQGYA 698

  Fly   703 YKVITHLKGMDTDSDLMYGTQEEQGQLLQLVLSASDLDCEDEKLPGEPGYRPSGSGGAVRRVGGL 767
            |||:.:|.||:.: ||...::|.|.||||.||:.||.|.|:|.:..|   ...|:....||...:
 Worm   699 YKVVNNLPGMELE-DLKLASKESQLQLLQQVLATSDADAEEEDVKEE---LADGTIRISRREATM 759

  Fly   768 SSMSGGDDAIYYEHRKKNIGSVHPLFKKFR 797
            :|||||..|.|:. :.|.|...|||||:||
 Worm   760 ASMSGGQGAQYHS-KAKAIAERHPLFKRFR 788

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hay	NP_001137931.1	rad25	70..795	CDD:273168	477/741 (64%)
		Helicase_C_3	86..208	CDD:290354	94/121 (78%)
		ResIII	331..488	CDD:282678	110/165 (67%)
		ERCC3_RAD25_C	512..756	CDD:292820	168/243 (69%)
xpb-1	NP_499487.1	rad25	60..786	CDD:273168	477/741 (64%)
		Helicase_C_3	76..198	CDD:290354	94/121 (78%)
		ResIII	322..485	CDD:282678	110/165 (67%)
		ERCC3_RAD25_C	509..751	CDD:292820	169/246 (69%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160156682
Domainoid	1	1.000	337	1.000	Domainoid score	I593
eggNOG	1	0.900	-	-		E1_COG1061
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H96
Inparanoid	1	1.050	960	1.000	Inparanoid score	I159
Isobase	1	0.950	-	0	Normalized mean entropy	S335
OMA	1	1.010	-	-		QHG60829
OrthoDB	1	1.010	-	-		D100698at2759
OrthoFinder	1	1.000	-	-		FOG0003639
OrthoInspector	1	1.000	-	-		oto19282
orthoMCL	1	0.900	-	-		OOG6_100822
Panther	1	1.100	-	-	LDO	PTHR11274
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R402
SonicParanoid	1	1.000	-	-		X2506
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	18	17.750