Protein Alignment hay and Ercc3

DIOPT Version :10

• Sequence 1: NP_524020.2
• Gene: hay / 39202
• FlyBaseID: FBgn0001179
• Length: 798
• Species: Drosophila melanogaster
• Sequence 2: NP_598419.1
• Gene: Ercc3 / 13872
• MGIID: 95414
• Length: 783
• Species: Mus musculus
• Alignment Length: 805
• Identity: 553/805 - (68%)
• Similarity: 656/805 - (81%)
• Gaps: 31/805 - (3%)

  Fly     1 MGPPKKSRKDRSGGDKFGKKRRAEDEAFTQLVDDNDSLDATES-EGIPGAASKNAETNDEQINTD 64
            ||  |:.|.||.  .|..|||:.|:|.     :|.|.:...|| |.:|.||.|..:.:..::  |
Mouse     1 MG--KRDRVDRD--KKKSKKRQYEEEE-----EDEDDIPGNESQEAVPSAAGKQVDESSTKV--D 54

  Fly    65 EYGAKDYRSQMQLRPDHGNRPLWVAPNGHVFLESFSPVYKHAHDFLIAISEPVCRPEHIHEYKLT 129
            ||||||||.||.|:.||.:|||||||:||:|||:||||||:|.|||:||:||||||.|:||||||
Mouse    55 EYGAKDYRQQMPLKGDHTSRPLWVAPDGHIFLEAFSPVYKYAQDFLVAIAEPVCRPTHVHEYKLT 119

  Fly   130 AYSLYAAVSVGLQTHDIVEYLKRLSKTSIPEGILEFIRLCTLSYGKVKLVLKHNKYFIESPHPEV 194
            ||||||||||||||.||.|||::||||.:|:||::||:|||:||||||||||||:||:||.||:|
Mouse   120 AYSLYAAVSVGLQTSDITEYLRKLSKTGVPDGIIQFIKLCTVSYGKVKLVLKHNRYFVESSHPDV 184

  Fly   195 LQKLLKDPVIQKCRLIRSEGE--DFIQGTLDGK-AITQFGTKLPPGATDKPTPDPAAAAGADGTT 256
            :|.||:||||::|||..:|||  :.|..|...| ||::...:...|      |..:....|..|:
Mouse   185 IQHLLQDPVIRECRLRNAEGEATELITETFTSKSAISKTAAEGSGG------PSTSQGVDAQATS 243

  Fly   257 AVPEDITDFYEKIDKEEEDEDEANLKTVSFEVAQEKIEVIQKRCIEIEHPLLAEYDFRNDTNNPD 321
            .:|:|:.||||::||:||:|:|.  :||||||.||.||.:|||||.:|:||||||||||||.|||
Mouse   244 DIPKDLFDFYEQMDKDEEEEEET--QTVSFEVKQEMIEELQKRCICLEYPLLAEYDFRNDTLNPD 306

  Fly   322 INIDLKPAAVLRPYQEKSLRKMFGNGRARSGVIVLPCGAGKSLVGVTACCTVRKRALVLCNSGVS 386
            |||||||.||||||||||||||||||||||||||||||||||||||||.||||||.|||.||.||
Mouse   307 INIDLKPTAVLRPYQEKSLRKMFGNGRARSGVIVLPCGAGKSLVGVTAACTVRKRCLVLGNSAVS 371

  Fly   387 VEQWKQQFKMWSTADDSMICRFTSEAKDKPMGCGILVTTYSMITHTQKRSWEAEQTMRWLQEQEW 451
            |||||.|||||||.|||.||||||:|||||:||.:.::||||:.||.|||||||:.|.||:.|||
Mouse   372 VEQWKAQFKMWSTIDDSQICRFTSDAKDKPIGCSVAISTYSMLGHTTKRSWEAERVMEWLKTQEW 436

  Fly   452 GIMVLDEVHTIPAKMFRRVLTIVQSHCKLGLTATLLREDDKIADLNFLIGPKLYEANWLELQKKG 516
            |:|:|||||||||:||||||||||:||||||||||:||||||.|||||||||||||||:|||..|
Mouse   437 GLMILDEVHTIPARMFRRVLTIVQAHCKLGLTATLVREDDKIVDLNFLIGPKLYEANWMELQNNG 501

  Fly   517 YIARVQCAEVWCPMSPEFYREYLTTKTSKKMLLYVMNPSKFRSCQFLIKYHEQRGDKTIVFSDNV 581
            |||:||||||||||||||||||:..||.|::|||.|||:|||:||||||:||:|.||.|||:|||
Mouse   502 YIAKVQCAEVWCPMSPEFYREYVAIKTKKRILLYTMNPNKFRACQFLIKFHERRNDKIIVFADNV 566

  Fly   582 FALKHYAIKMNKPFIYGPTSQNERIQILQNFKFNSKVNTIFVSKVADTSFDLPEANVLIQISSHG 646
            ||||.|||::|||:|||||||.||:|||||||.|.|:||||:|||.|||||||||||||||||||
Mouse   567 FALKEYAIRLNKPYIYGPTSQGERMQILQNFKHNPKINTIFISKVGDTSFDLPEANVLIQISSHG 631

  Fly   647 GSRRQEAQRLGRILRAKKGAIAEEYNAFFYTLVSQDTMEMSYSRKRQRFLVNQGYSYKVITHLKG 711
            ||||||||||||:||||||.:|||||||||:||||||.||:||.|||||||:||||:||||.|.|
Mouse   632 GSRRQEAQRLGRVLRAKKGMVAEEYNAFFYSLVSQDTQEMAYSTKRQRFLVDQGYSFKVITKLAG 696

  Fly   712 MDTDSDLMYGTQEEQGQLLQLVLSASDLDCEDEKLPGEPGYRPSGSGGAVRRVGGLSSMSGGDDA 776
            |: :.:|.:.|:|||.||||.||:|:|||.|:|.:.||.|.|   ||.|.||.|.:||:||.||.
Mouse   697 ME-EEELAFSTKEEQQQLLQKVLAATDLDAEEEVVAGEFGSR---SGQASRRCGTMSSLSGADDT 757

  Fly   777 IYYEHR----KKNIGSVHPLFKKFR 797
            :|.|:.    |.:...||||||:||
Mouse   758 VYMEYHSSRSKASSKHVHPLFKRFR 782

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hay	NP_524020.2	rad25	70..795	CDD:273168	523/731 (72%)
Ercc3	NP_598419.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..52		21/59 (36%)
		Nuclear localization signal. /evidence=ECO:0000255	6..18		6/13 (46%)
		rad25	60..780	CDD:273168	523/731 (72%)
		DEVH box	442..445		2/2 (100%)