Protein Alignment hay and ercc3

DIOPT Version :10

• Sequence 1: NP_524020.2
• Gene: hay / 39202
• FlyBaseID: FBgn0001179
• Length: 798
• Species: Drosophila melanogaster
• Sequence 2: NP_001123812.1
• Gene: ercc3 / 100170563
• XenbaseID: XB-GENE-1009820
• Length: 786
• Species: Xenopus tropicalis
• Alignment Length: 806
• Identity: 553/806 - (68%)
• Similarity: 650/806 - (80%)
• Gaps: 30/806 - (3%)

  Fly     1 MGPPKKSRKDRSGGDKFGKKRRAEDEAFTQLVDDNDSLDATE-SEGIPGAASKNAETNDEQINTD 64
            ||  |:.:.||....|| |:|..|:|.     ::.:.:...| .|.:|.||.|  :.::.....|
 Frog     1 MG--KRDKADRGDKKKF-KRRHYEEED-----EEEEEVPGGEYQEAVPSAAGK--QVDEAGTKQD 55

  Fly    65 EYGAKDYRSQMQLRPDHGNRPLWVAPNGHVFLESFSPVYKHAHDFLIAISEPVCRPEHIHEYKLT 129
            ||||||||.||.|:.||.:|||||||:||:|||:||||||:|.|||:|||||||||.|.||||||
 Frog    56 EYGAKDYRLQMPLKMDHSSRPLWVAPDGHIFLEAFSPVYKYAQDFLVAISEPVCRPSHTHEYKLT 120

  Fly   130 AYSLYAAVSVGLQTHDIVEYLKRLSKTSIPEGILEFIRLCTLSYGKVKLVLKHNKYFIESPHPEV 194
            ||||||||||||||.||||||::||||.:||||::||:|||:||||||||||||:||:||.||||
 Frog   121 AYSLYAAVSVGLQTSDIVEYLQKLSKTGVPEGIVQFIKLCTVSYGKVKLVLKHNRYFVESTHPEV 185

  Fly   195 LQKLLKDPVIQKCRLIRSEGE--DFIQGT-LDGKAITQFGTKLPPGATDKPTPDPAAAAGADGTT 256
            :|:||:|.||:.|||..:||.  |.|..| |...||::.......|.:....|:     |.|.|.
 Frog   186 IQELLQDSVIRGCRLRDAEGNETDLITETFLSKSAISKASETAASGPSTSQVPE-----GQDKTN 245

  Fly   257 AVPEDITDFYEKIDKEEEDEDEANLKTVSFEVAQEKIEVIQKRCIEIEHPLLAEYDFRNDTNNPD 321
             ||.|:.:|||::|||||:|:|.  :||||||.|:.||.:||:||.:|:||||||||||||.|||
 Frog   246 -VPADLFEFYEQMDKEEEEEEET--QTVSFEVKQDNIEELQKQCIHLEYPLLAEYDFRNDTMNPD 307

  Fly   322 INIDLKPAAVLRPYQEKSLRKMFGNGRARSGVIVLPCGAGKSLVGVTACCTVRKRALVLCNSGVS 386
            |||||||.||||||||||||||||||||||||||||||||||||||||.||||||.|||.||.||
 Frog   308 INIDLKPTAVLRPYQEKSLRKMFGNGRARSGVIVLPCGAGKSLVGVTAACTVRKRCLVLGNSAVS 372

  Fly   387 VEQWKQQFKMWSTADDSMICRFTSEAKDKPMGCGILVTTYSMITHTQKRSWEAEQTMRWLQEQEW 451
            |||||.|||||||.|||.||||||:|||||:||.|.::||||:.||.|||||||:.|.||:.|||
 Frog   373 VEQWKAQFKMWSTIDDSQICRFTSDAKDKPIGCSIAISTYSMLGHTTKRSWEAERVMEWLKSQEW 437

  Fly   452 GIMVLDEVHTIPAKMFRRVLTIVQSHCKLGLTATLLREDDKIADLNFLIGPKLYEANWLELQKKG 516
            |:|:||||||||||||||||||||:||||||||||:||||||.|||||||||||||||:|||..|
 Frog   438 GLMILDEVHTIPAKMFRRVLTIVQAHCKLGLTATLVREDDKIVDLNFLIGPKLYEANWMELQNNG 502

  Fly   517 YIARVQCAEVWCPMSPEFYREYLTTKTSKKMLLYVMNPSKFRSCQFLIKYHEQRGDKTIVFSDNV 581
            |||:||||||||||||||||||:..||.|::|||.|||:|||:||||||:||:|.||.|||:|||
 Frog   503 YIAKVQCAEVWCPMSPEFYREYVAIKTKKRILLYTMNPNKFRACQFLIKFHERRNDKIIVFADNV 567

  Fly   582 FALKHYAIKMNKPFIYGPTSQNERIQILQNFKFNSKVNTIFVSKVADTSFDLPEANVLIQISSHG 646
            ||||.|||:::||:|||||||.||:.||||||.|.|:||||:|||.|||||||||||||||||||
 Frog   568 FALKEYAIRLSKPYIYGPTSQGERMHILQNFKHNPKINTIFISKVGDTSFDLPEANVLIQISSHG 632

  Fly   647 GSRRQEAQRLGRILRAKKGAIAEEYNAFFYTLVSQDTMEMSYSRKRQRFLVNQGYSYKVITHLKG 711
            ||||||||||||:||||||.:|||||||||:||||||.||:||.|||||||:||||:||||.|.|
 Frog   633 GSRRQEAQRLGRVLRAKKGMVAEEYNAFFYSLVSQDTQEMAYSTKRQRFLVDQGYSFKVITKLAG 697

  Fly   712 MDTDSDLMYGTQEEQGQLLQLVLSASDLDCEDEKLPGEPGYRPSGSGGAVRRVGGLSSMSGGDDA 776
            |: :..|.:..:|:|.||||.||:|||||.|:|.:.||.|.|.:..  ..||||.:|||||.|||
 Frog   698 ME-EEHLAFSNKEDQQQLLQKVLAASDLDAEEEVVVGEFGSRSTMQ--VSRRVGTMSSMSGADDA 759

  Fly   777 IYYE-HRKKNIGS----VHPLFKKFR 797
            :|.| |..:|.|:    ||||||:||
 Frog   760 VYMEYHTSRNRGASNKHVHPLFKRFR 785

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hay	NP_524020.2	rad25	70..795	CDD:273168	527/732 (72%)
ercc3	NP_001123812.1	rad25	61..783	CDD:273168	527/732 (72%)