Protein Alignment Rbfox1 and Rbfox1

DIOPT Version :9

• Sequence 1: NP_001246707.1
• Gene: Rbfox1 / 39198
• FlyBaseID: FBgn0052062
• Length: 962
• Species: Drosophila melanogaster
• Sequence 2: XP_006522218.3
• Gene: Rbfox1 / 268859
• MGIID: 1926224
• Length: 550
• Species: Mus musculus
• Alignment Length: 466
• Identity: 157/466 - (33%)
• Similarity: 196/466 - (42%)
• Gaps: 128/466 - (27%)

  Fly   262 SAMQNAGGGGNTGGGGGGGG------------GGTPSSPLSNSPSSATA----------SQAGGC 304
            |.:....|||..|.|.||.|            ..:...||||..|...|          |::|..
Mouse    17 SPLDGCLGGGRAGTGAGGRGRSVRIDIRGCLWQASRRQPLSNVSSEKVAGGRVHLWGRGSESGPG 81

  Fly   305 GLTLNGS------------ATE--GSMSGDTSPVASGEP---LLQTPPAHQQQQQQQQPLLCSSP 352
            |...:||            |:|  ..:.||::..|..|.   |.|.....::|.:..|.
Mouse    82 GGWSSGSLERQWQDANVFAASELHRDIKGDSNNCAQTEDRKVLRQQMNCEREQLRGNQE------ 140

  Fly   353 TSMQSSGTSVTGSSIASGTLAATSSSGVGLLPTTGLDSIANGGAP------TGCAVVPASTSQVI 411
                        ::.|..|:|...:|.....|..|:.:......|      ||...||..|..:.
Mouse   141 ------------AAAAPDTMAQPYASAQFAPPQNGIPAEYTAPHPHPAPEYTGQTTVPDHTLNLY 193

  Fly   412 ----AHLNAAAAAASGIVSPSANVATSLSSALVPAQSVAAVAAASLDAKSQPKRLHVSNIPFRFR 472
                .|...:|..::..||   ..||....|...........:.:.::|||||||||||||||||
Mouse   194 PPTQTHSEQSADTSAQTVS---GTATQTDDAAPTDGQPQTQPSENTESKSQPKRLHVSNIPFRFR 255

  Fly   473 DPDLRAMFGQFGTILDVEIIFNERGSKGFGFVTFANSNDAERARERLHGTVVEGRKIEVNNATAR 537
            |||||.||||||.|||||||||||||||||||||.||.||:||||:|||||||||||||||||||
Mouse   256 DPDLRQMFGQFGKILDVEIIFNERGSKGFGFVTFENSADADRAREKLHGTVVEGRKIEVNNATAR 320

  Fly   538 VQTKKVTAVP-------NVVLTKDGAIPAP------ALVC------------------------V 565
            |.|.|.|..|       |.|:   ||:.:|      .|:|                        .
Mouse   321 VMTNKKTVNPYTNGWKLNPVV---GAVYSPDFYAGTVLLCQANQEGSSMYSGPSSLVYTSAMPGF 382

  Fly   566 QWPEAAVAAAMRGVAIQ-RGH--------------VGVVGATPYHHPHHPHHHPALLAASAAAAQ 615
            .:|.|..|||.||..:: ||.              :...|...|..|.:.:   .||....||.:
Mouse   383 PYPAATAAAAYRGAHLRGRGRTVYNTFRAAAPPPPIPAYGGVVYQEPVYGN---KLLQGGYAAYR 444

  Fly   616 QQQQRQLAAAA 626
            ..|.....|||
Mouse   445 YAQPTPATAAA 455

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rbfox1	NP_001246707.1	RRM	<454..>542	CDD:223796	78/87 (90%)
		RRM_FOX1_like	460..535	CDD:240853	68/74 (92%)
Rbfox1	XP_006522218.3	PRK03427	<131..>248	CDD:235124	50/126 (40%)
		RRM_FOX1_like	243..318	CDD:240853	56/87 (64%)
		Fox-1_C	379..468	CDD:372095	3/3 (100%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167830962
Domainoid	1	1.000	127	1.000	Domainoid score	I5353
eggNOG	1	0.900	-	-		E1_KOG0125
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001186
OrthoInspector	1	1.000	-	-		otm42644
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR15597
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2530
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	10	9.830