Protein Alignment Rbfox1 and fox-1

DIOPT Version :9

• Sequence 1: NP_001246707.1
• Gene: Rbfox1 / 39198
• FlyBaseID: FBgn0052062
• Length: 962
• Species: Drosophila melanogaster
• Sequence 2: NP_001317857.1
• Gene: fox-1 / 180549
• WormBaseID: WBGene00001484
• Length: 429
• Species: Caenorhabditis elegans
• Alignment Length: 574
• Identity: 168/574 - (29%)
• Similarity: 216/574 - (37%)
• Gaps: 199/574 - (34%)

  Fly   294 SSATASQAGGCG-LTLNG-----------SATEGSMSGDTSPVASGEPLL-QTPPAHQQ--QQQQ 343
            |:||.:....|. :.:|.           |||.........|:.....|| |...||||  .||.
 Worm     9 STATHASLNACDPIVVNSEALPMQALYQLSATGAQQQNQQIPIGLSNSLLYQQLAAHQQIAAQQH 73

  Fly   344 QQPLLCSSPTSMQSSGTSVTGSSIASGTLAATSSSGVGLLPTTGLDSIANGGA---PTGCAVVPA 405
            ||.|..|:....|::            .:.|||:..:    ...:::..:|..   |.....:..
 Worm    74 QQQLAVSAAHQTQNN------------IMLATSAPSL----INHMENSTDGKVKDDPNSDYDLQL 122

  Fly   406 STSQVIAHLNAAAAAASGIVSPSANVATSLSSALV--PAQSVAAVAAASLDAKSQ---------- 458
            |..|.:|  .||.||..|        .|.:...:|  ..|.|.|..|.|.:..:.
 Worm   123 SIQQQLA--AAAQAAQMG--------QTQIGPQIVGQQGQPVVATTAGSTNGSAAVTQPDPSTSS 177

  Fly   459 ----PKRLHVSNIPFRFRDPDLRAMFGQFGTILDVEIIFNERGSKGFGFVTFANSNDAERARERL 519
                ||||||||||||||||||:.||.:||.:.||||||||||||||||||.....||||||:.|
 Worm   178 GPDGPKRLHVSNIPFRFRDPDLKTMFEKFGVVSDVEIIFNERGSKGFGFVTMERPQDAERARQEL 242

  Fly   520 HGTVVEGRKIEVNNATARVQTKKVTAVPNVVLTKDGAIPAPALVCVQWPEAAVAAAMRGVAIQRG 584
            ||:::||||||||.|||||.:|||.                       |...:...|.
 Worm   243 HGSMIEGRKIEVNCATARVHSKKVK-----------------------PTGGILDQMN------- 277

  Fly   585 HVGVVGATPYHHPHHPHHHPALLAASAAAAQQQQQRQLAAAAVATAAVAQQQQQQQQAVVQQQQQ 649
                                .|:|.||.|||.|..|   |..:.:..|||....:..|::..
 Worm   278 --------------------PLMAQSALAAQAQMNR---ALLLRSPLVAQSLLGRGAALIPG--- 316

  Fly   650 QVAAAAQQQHQQQQQQQQQAVQQQQAVQQQQQHQQQQQQQQQQQHAAVAAAAAAASHPHMHAAHA 714
                                 .||.|.|.|                     ||.|.:|
 Worm   317 ---------------------MQQPAFQLQ---------------------AALAGNP------- 332

  Fly   715 HAHAHALGPQLAQLQAVAVPTAASNAAALQQSLAAAIQNPSGNPNAAAAAAAYAARLSAATGATQ 779
                      |||||...:   ..||||||.:   |:|..:...:.||..||..|.       .|
 Worm   333 ----------LAQLQGQPL---LFNAAALQTN---ALQQSAFGMDPAAVQAALLAN-------EQ 374

  Fly   780 SPQTAAAAAAAASMAASANAANNAAALHGFAPVYYDPFLAAAA----SADPNLR 829
            :....|||||...:.:|.||:       .|...|....||.|:    ..:|.||
 Worm   375 ARFQLAAAAAQGRIPSSGNAS-------AFGEQYLSNALATASLPSYQMNPALR 421

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rbfox1	NP_001246707.1	RRM	<454..>542	CDD:223796	62/101 (61%)
		RRM_FOX1_like	460..535	CDD:240853	56/74 (76%)
fox-1	NP_001317857.1	RRM_FOX1_like	183..258	CDD:409841	56/74 (76%)
		PABP-1234	<185..417	CDD:130689	119/366 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160167918
Domainoid	1	1.000	109	1.000	Domainoid score	I3982
eggNOG	1	0.900	-	-		E1_KOG0125
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001186
OrthoInspector	1	1.000	-	-		otm14423
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR15597
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2530
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.870