DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ir67b and Ir68b

DIOPT Version :9

Sequence 1:	NP_648393.1	Gene:	Ir67b / 39194	FlyBaseID:	FBgn0036083	Length:	574	Species:	Drosophila melanogaster
Sequence 2:	NP_648548.1	Gene:	Ir68b / 39378	FlyBaseID:	FBgn0036250	Length:	635	Species:	Drosophila melanogaster

Alignment Length:	549	Identity:	108/549 - (19%)
Similarity:	194/549 - (35%)	Gaps:	129/549 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    87 EHLDRGLYYLANWLWEYHHLEVLIFFNGGSYDKL---IQIFSR--------CFNEGFVNVLVMLP 140
            :|:.:   ||..|.....| ::|..|.|....||   :.|..|        .|..|.:.|:..|.
  Fly   116 KHMHK---YLFVWPNAGRH-QLLRLFRGSWAKKLLYGLAITGRENGTFDFDPFAWGGLQVIQRLD 176

  Fly   141 GSDELYTFMPYQDLKILNLKSIKEFYS--------LSRKKMDLNGYNITSGLV------IAGAPR 191
            |.      :||. .|:.:|:.....:|        :.|..::..||....|:.      :..|..
  Fly   177 GE------VPYA-RKVKDLRGYPLRFSMFTDPLMAMPRSPVETAGYQAVDGVAARVVGEMLNASV 234

  Fly   192 WFSF---RDRQNRLILTGYMLRMIVDFT---NHFNGSVRLMNVLTVNDGLELLANRTIDFFPFLI 250
            .:.|   .:...|.:..|....::.|..   .||..:.|.: :..:...:|:|       :|:..
  Fly   235 TYVFPEDNESYGRCLPNGNYTGVVSDIVGGHTHFAPNSRFV-LDCIWPAVEVL-------YPYTR 291

  Fly   251 RPLKSFSMSNILYLENCGLIVPTSRPLPNWVYLLRPYAFDTWIAWLIMLIYCSLAL--------R 307
            |              |..|:||.|...|.::..:|.:....|...|:.|:...|..        |
  Fly   292 R--------------NLHLVVPASAIQPEYLIFVRVFRRTVWYLLLVTLLVVVLVFWVMQRLQRR 342

  Fly   308 ILSKGQISISAAFLKVLRLVMYLSGSRDMGTRPTTR-------RLFLFVILTTSGFILTNLYVAQ 365
            |..:|.|...|.:.::|.:.    |...:| .|..|       |.||...:..| ::|:.:|.|:
  Fly   343 IPRRGVIQFQATWYEILEMF----GKTHVG-EPAGRLSSFSSMRTFLMGWILFS-YVLSTIYFAK 401

  Fly   366 LSSNSAAGLYEKQINTWEDLDKSD----SIWPLIDVDIKTMEK----LIPDRTKLLKKIVPTLEA 422
            |.|......||:|::..:||...|    ::..:.|.....:.:    |:.:|::.|...:.|...
  Fly   402 LESGFVRPSYEEQVDRVDDLVHLDVHIYAVTTMYDAVRSALTEHQYGLLENRSRQLPLGIATSYY 466

  Fly   423 DVDTYRRNLNTSCIHSGFFDRIDFALYQQKFLRFPIFRKFPHLLYQQPLQISAAF----GRPYLQ 483
            .....||:...:.|...|..|...|:........|.:    |:..:....:...:    |.|:|.
  Fly   467 QPVVRRRDRRAAFIMRDFHARDFLAITYDSQAERPAY----HIAREYLRSMICTYILPRGSPFLH 527

  Fly   484 LFNWFVRKIFESGIY--LKMKDDAYRHG-----------------IQSGLLNLAFRDRHLEVKSN 529
            ..........|.|.:  .:..|...|.|                 ..||...||.|::.: |.:.
  Fly   528 RLESLYSGFLEHGFFEHWRQMDLITRVGASPDAEEFLEDLGDQTDTDSGSNELAIRNKKV-VLTL 591

  Fly   530 DV---EYYYLIAGLWFGGLTLATVCFLLE 555
            |:   .:|     ||..|:.::.:.|.:|
  Fly   592 DILQGAFY-----LWSVGIGISCLGFAVE 615

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ir67b	NP_648393.1	None
Ir68b	NP_648548.1	Lig_chan	333..607	CDD:278489	57/289 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR42643
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100