DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ir67b and Ir7c

DIOPT Version :9

Sequence 1:	NP_648393.1	Gene:	Ir67b / 39194	FlyBaseID:	FBgn0036083	Length:	574	Species:	Drosophila melanogaster
Sequence 2:	NP_001245572.1	Gene:	Ir7c / 31692	FlyBaseID:	FBgn0029966	Length:	625	Species:	Drosophila melanogaster

Alignment Length:	583	Identity:	125/583 - (21%)
Similarity:	203/583 - (34%)	Gaps:	189/583 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    96 LANW----LWEYHHLEVLIFFNGGSY------------------DKLIQIFSRCFNEGFVNVLVM 138
            :|.|    |..|..||:.:...|..|                  :.|..:|.|..|...:||.|.
  Fly    92 IAIWFLDSLRSYFRLEMYLNQLGSPYKRNGFFLVIYTGLEDQPMESLKIMFRRLLNMYVLNVNVF 156

  Fly   139 L--PGSDELYTFMPYQDLKILNLKSIKEFYSLSRKKMDL----NGYNITSGL------------- 184
            |  .|:..|||:.||......:  |:..:|:..:   ||    ||:.:|..|
  Fly   157 LQRDGTVHLYTYYPYGPHHCQS--SLPVYYTAFQ---DLAAPANGFGLTKPLFPRKLTNMHGCEM 216

  Fly   185 VIAGAPRWFSFRDRQNRLI--------------LTGYMLRMIVDFTNHFNGSVRLMNVLTVNDGL 235
            |:|      :|..|...:|              :.|.:.|.:.:   ..|.:::|:.....|.|
  Fly   217 VVA------TFEHRPYVIIEDDPKTPGGRSIHGIEGLIFRSLAE---RMNFTIKLVEQKDKNRG- 271

  Fly   236 ELL----------------ANRTIDFFPF------LIRPLKSF-SMSNILYLENCGLIVPTSRPL 277
            |:|                .|.|...|.:      |:.|..|: |...:|.:.:.|.|.|..|
  Fly   272 EILPDGNFTGILKMMVDGEVNLTFVCFMYSKARSDLMLPSTSYTSFPIVLVVPSGGSISPMGR-- 334

  Fly   278 PNWVYLLRPYAFDTWIAWLIMLIY-----CSLALRIL---------SKGQISISAAFLKVLRLVM 328
                 |.||:.:..|...|:.||:     |.|.:..|         .:.::.....:..:|..:.
  Fly   335 -----LTRPFRYIIWSCILVSLIFGFVLICLLKITALPGLRNLVLGRRNRLPFMGMWASLLGGLA 394

  Fly   329 YLSGSRDMGTRPTTRRLFLFVILTTSGFILTNLYVAQLSSNSAAGLYEKQINTWEDLDKSDSIWP 393
            ..:..|:.     .|.:.:..:|.|  .||...|..||            ....:|::....|..
  Fly   395 LYNPQRNF-----ARYILVMWLLQT--LILRAAYTGQL------------YLLLQDVEMRSPIKS 440

  Fly   394 LIDVDIKTME-KLIPDRTKLLKKIVPT------LEADVDTYRRNLNTSCIHSGFFDRIDFALYQQ 451
            |.:|..|..| :::|....:.|..:||      |..:...||       :.......|..||.|.
  Fly   441 LSEVLAKDYEFRILPALRTIFKDSMPTTNFHAVLSLEESLYR-------LRDEDDPGITVALLQP 498

  Fly   452 KFLRFPIFRKFP---HL------LYQQPLQISAAFGRPYLQLFNWFVRKI-------FESGI--- 497
            ...:|. ||..|   ||      |...||..       |::..::|.|:|       ..|||
  Fly   499 TVNQFD-FRSGPNKRHLTVLPDPLMTAPLTF-------YMRPHSYFKRRIDRLIMAMMSSGIVAR 555

  Fly   498 YLKMKDDAYRHGIQSGLLNLAFRDRHLEVKSNDVEYYYLIAGLWF--GGLTL-ATVCFLLELL 557
            |.||..|..:.         ..:.|:||.|...:   :.::|::.  .||.| |.:.|:||:|
  Fly   556 YRKMYMDRIKR---------VSKRRNLEPKPLSI---WRLSGIFVCCAGLYLVALIVFILEIL 606

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ir67b	NP_648393.1	None
Ir7c	NP_001245572.1	Lig_chan-Glu_bd	225..287	CDD:214911	9/65 (14%)
Ir7c	NP_001245572.1	Lig_chan	343..593	CDD:278489	59/295 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR42643
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010