DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG12362 and ARI5

DIOPT Version :9

Sequence 1:	NP_648392.1	Gene:	CG12362 / 39193	FlyBaseID:	FBgn0036082	Length:	511	Species:	Drosophila melanogaster
Sequence 2:	NP_001184920.1	Gene:	ARI5 / 837099	AraportID:	AT1G05890	Length:	594	Species:	Arabidopsis thaliana

Alignment Length:	566	Identity:	164/566 - (28%)
Similarity:	259/566 - (45%)	Gaps:	119/566 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MNSEMEFSDEDHGD-SHRSLLTHMSCENDSDSED--------------------------TCTEI 38
            |:|:.:..|.|..| .:.|..|:  .:||||..|                          :|..:
plant     1 MDSDDDMHDMDSVDYDYYSGGTY--DDNDSDETDFGFGEADTDDAAIIASYRSKVASILVSCFGL 63

  Fly    39 LLPE--------------------------NSNSPETEDFVYKVLSVDQIVQHQRNIIDEVNNVL 77
            ||..                          |||        |.||..:.|.:||.:.:..|:.||
plant    64 LLQRWRMLEAVFCLFVCFFFFGLRLLLYSCNSN--------YVVLKEEDIRRHQNDDVGRVSAVL 120

  Fly    78 NLPPQVTRIILNHFKWDKESLFENYFESNPKDFFQRAHVLNPFEKKIERE------SAASTSCAI 136
            ::.......:|.|:.|....:.:.:|..               |:::.|.      ...:|....
plant   121 SITDVEASTLLLHYHWSVSKVNDEWFAD---------------EERVRRTVGILEGPVVTTPDGR 170

  Fly   137 PQLCGICFCS--CDELIGLGCGHNFCAACWKQYLANKTCSEGL-ANTIKCPAANCEILV--DYIS 196
            ...|||||.|  .:|::.:.|||.|||.||..|::. |.::|. ...:|||..:|...:  |.|.
plant   171 EFTCGICFDSYTLEEIVSVSCGHPFCATCWTGYIST-TINDGPGCLMLKCPDPSCPAAIGRDMID 234

  Fly   197 FLKLADDSEVVERYQQLITNTFVECNMLMRWCPAPNCSHAVK-AVCAEPRAVLCKCGHEFCFACG 260
            .|...:|.   |:|.:....::||.|..|:|||||.|.||:. |...|...|.|.|.|.||:.|.
plant   235 KLASKEDK---EKYYRYFLRSYVEVNREMKWCPAPGCEHAIDFAGGTESYDVSCLCSHSFCWNCT 296

  Fly   261 ENWHEPASCSSLKKWVKKCLEDSETSNWIAQNTKECPKCNVTIEKDGGCNHMVCKNPSCRYDFCW 325
            |..|.|..|.::.||:.|...:||..|||..|:|.||||...|||:.||.||.| .|.|:::|||
plant   297 EEAHRPVDCDTVGKWILKNSAESENMNWILANSKPCPKCKRPIEKNHGCMHMTC-TPPCKFEFCW 360

  Fly   326 VCLGSWEPHG---SSWYSCNRFDEEEAKQ------ARLAQQKYRSSMARYLHYYNRYSNHMQSLK 381
            :||.:|..||   ..:|:|||:  |.|||      |...::..::|:.||.|||.|::::..|.:
plant   361 LCLNAWTEHGERTGGFYACNRY--EAAKQEGLYDEAERRREMAKNSLERYTHYYERWASNQVSRQ 423

  Fly   382 ME----NKLYSNIQAKMDDMQ---EEMSWIEVQFLRDAVDVLCQCRTTLMYSYVFAFYLMNNNQK 439
            ..    .|:.|....|:.|:|   |.    :::|:.:|...:.:||..|.::|.:.:||.::.:|
plant   424 KAMGDLQKMQSEKLGKLSDIQCTPES----QLKFIAEAWLQIIECRRVLKWTYAYGYYLQDHAKK 484

  Fly   440 IIFEDNQKDMEMATEKLSECLEREITVKNIYEVKQKVLDLSHYCQK 485
            ..||..|.:.|...|:|.:|:|::|.|..:.|...:  :.:|:..|
plant   485 PFFEYLQGEAESGLERLHKCVEKDIEVFELAEGPSE--EFNHFRTK 528

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12362	NP_648392.1	IBR	208..269	CDD:214763	26/61 (43%)
CG12362	NP_648392.1	IBR	273..331	CDD:279784	29/57 (51%)
ARI5	NP_001184920.1	IBR	243..305	CDD:214763	26/61 (43%)
ARI5	NP_001184920.1	IBR	<327..366	CDD:279784	21/39 (54%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	76	1.000	Domainoid score	I3141
eggNOG	1	0.900	-	-		E1_KOG1815
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	252	1.000	Inparanoid score	I1022
OMA	1	1.010	-	-		QHG54219
OrthoDB	1	1.010	-	-		D469819at2759
OrthoFinder	1	1.000	-	-		FOG0000379
OrthoInspector	1	1.000	-	-		mtm1045
orthoMCL	1	0.900	-	-		OOG6_100963
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1756
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	11	10.740