Protein Alignment CG12362 and ARI4

DIOPT Version :10

• Sequence 1: NP_648392.1
• Gene: CG12362 / 39193
• FlyBaseID: FBgn0036082
• Length: 511
• Species: Drosophila melanogaster
• Sequence 2: NP_189409.1
• Gene: ARI4 / 822394
• AraportID: AT3G27720
• Length: 493
• Species: Arabidopsis thaliana
• Alignment Length: 512
• Identity: 152/512 - (29%)
• Similarity: 239/512 - (46%)
• Gaps: 97/512 - (18%)

  Fly    22 HMSCENDSDSEDTCTEILLPEN----SNSPETEDFVYKVLSVDQIVQHQRNIIDEVNNVLNLPPQ 82
            :||.|   :.||.|......::    ||:.|::            :||.|....:|...|::...
plant     5 YMSLE---EEEDNCYPSEFDDHDQMCSNAEESD------------LQHSREPTSQVMEFLSVTEN 54

  Fly    83 VTRIILNHFKWDKESLFENYFESNPKDFFQRAHVLNPFEKKIERESAASTSCAIPQLCGICFCSC 147
            ..|.:|..::|:.:.||..|.:......|.||.. ...|.|.|.|...
plant    55 QARTLLIQYQWNVDKLFSVYTDQGKDVLFSRAEE-EEGEDKEEEEGGE----------------- 101

  Fly   148 DELIGLGCGHNFCAACWKQYLANKTCSEGLANTIKCPAANCEILVDYISFLKLADDSEVVERYQQ 212
            ||....| |.:..|   ::...::...||:.:..: .....:..|..:|       :|:.|::.:
plant   102 DEEEEEG-GEDEEA---EEGGEDEEAEEGVEDEEE-EEDEKDDEVQLVS-------TELAEKFDR 154

  Fly   213 LITNTFVECNMLMRWCPA-PNCSHAVKAV--CAEPRAVLCKCGHEFCFACGENWHEPASCSSLKK 274
            .:..::||.|.:::|||: |:|.:|::.:  ..:...|.|.||.:|||:|....|.|.||...|.
plant   155 FLIESYVEDNNMVKWCPSTPHCGNAIRNIKDDGDVDEVECSCGLQFCFSCLSESHSPCSCLMWKL 219

  Fly   275 WVKKCLEDSETSNWIAQNTKECPKCNVTIEKDGGCNHMVCKNPSCRYDFCWVC---LGSWEPHGS 336
            |.|||.::|||.||:..|||.||||:..|:|..|||||.||   |...|||:|   .|....:.|
plant   220 WKKKCEDESETVNWMTVNTKLCPKCSKPIQKRDGCNHMTCK---CGQHFCWLCGQATGRDHSYSS 281

  Fly   337 -SWYSCNRFDEEEAKQARLAQQKYRSSMARYLHYYNRYSNHMQSLKMENKLYSNI--------QA 392
             :.:||.|:.||:.:|...||:    .:.||.||:.||..|:.|||:|:||..:|        :.
plant   282 IAGHSCGRYKEEKVRQLERAQR----DLDRYTHYHYRYKAHIDSLKLEDKLKKSILKKAVLNSET 342

  Fly   393 KMDDMQEEMSWIEVQFLRDAVDVLCQCRTTLMYSYVFAFYLM-------------NNNQKIIFED 444
            |...:.:|.|||     .|||:.|.:.|..|.|||.|.||:.             .|.:|.:|||
plant   343 KDQKVFKEYSWI-----IDAVNRLFRSRRILSYSYPFVFYMFGKELFKDDMSDEERNIKKNLFED 402

  Fly   445 NQKDMEMATEKLSECLEREITVKNIYEVKQKVLDLSHYCQKRRHVL--LCHVREGYE 499
            .|:.:|...|:||:.||...   :.|: .:||:::..:......|:  ||  :|.||
plant   403 QQQQLEGNVERLSKILEEPF---DEYD-HEKVVEMMRHLTNLTAVVDNLC--KEMYE 453

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12362	NP_648392.1	RING-HC_RBR_HHARI	138..194	CDD:438288	8/55 (15%)
		BRcat_RBR_HHARI-like	203..284	CDD:439004	28/83 (34%)
		Rcat_RBR_HHARI-like	288..345	CDD:439017	27/60 (45%)
		Ariadne	346..>480	CDD:466073	51/154 (33%)
ARI4	NP_189409.1	BRcat_RBR_ANKIB1	157..223	CDD:439007	23/65 (35%)
		Rcat_RBR_ARI1-like	235..288	CDD:439037	24/55 (44%)
		Ariadne	291..>487	CDD:466073	57/178 (32%)