DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG12362 and ARI9

DIOPT Version :9

Sequence 1:	NP_648392.1	Gene:	CG12362 / 39193	FlyBaseID:	FBgn0036082	Length:	511	Species:	Drosophila melanogaster
Sequence 2:	NP_180736.1	Gene:	ARI9 / 817734	AraportID:	AT2G31770	Length:	543	Species:	Arabidopsis thaliana

Alignment Length:	490	Identity:	144/490 - (29%)
Similarity:	240/490 - (48%)	Gaps:	69/490 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 MEFSDEDHGDSHRSLLTHMSCE--------NDSDSEDTCTEILLPENSNSPETEDFVYKVLSVDQ 61
            |:|||:|       ::.:.|.|        |:||..:...:.::|...:        |.:|..:.
plant     1 MDFSDDD-------MIDNKSGEENYSYGGGNESDDYNDVVDTIIPSEKS--------YVILKEED 50

  Fly    62 IVQHQRNIIDEVNNVLNLPPQVTRIILNHFKWDKESLFENYFESNPK-------------DFFQR 113
            |::.||:.|:.|:::|:|......::|.|:.|....:.:.:|....:             ||
plant    51 ILKLQRDDIERVSSILSLSQVEVIVLLLHYNWCVSKVEDEWFTDEERIRKAVGLLKEPVVDF--- 112

  Fly   114 AHVLNPFEKKIERESAASTSCAIPQL-CGICFCSC--DELIGLGCGHNFCAACWKQYLANKTCSE 175
                |..||        ...|....: |||||.|.  :|:..:.|||.:|..||..|:..|....
plant   113 ----NGGEK--------DKKCRKVNIQCGICFESYTREEIARVSCGHPYCKTCWAGYITTKIEDG 165

  Fly   176 GLANTIKCPAANCEILVDYISFLKLADDSEVVERYQQLITNTFVECNMLMRWCPAPNCSHAVKAV 240
            .....:|||..:|...|.. ..::...:::|.|:|.:.|..::||....::|||:|.|.:||:..
plant   166 PGCLRVKCPEPSCSAAVGK-DMIEDVTETKVNEKYSRYILRSYVEDGKKIKWCPSPGCGYAVEFG 229

  Fly   241 CAEPRA--VLCKCGHEFCFACGENWHEPASCSSLKKWVKKCLEDSETSNWIAQNTKECPKCNVTI 303
            .:|..:  |.|.|.:.||:.|.|:.|.|..|.::.||:.|..::||..||:..|:|.||:|...|
plant   230 GSESSSYDVSCLCSYRFCWNCSEDAHSPVDCDTVSKWIFKNQDESENKNWMLANSKPCPECKRPI 294

  Fly   304 EKDGGCNHMVCKNPSCRYDFCWVCLGSWEPHGSSWYSCNRFDEEEAKQARLAQQKYRSSMARYLH 368
            ||:.|||||.|..| |.::|||:||.::..|..   :||||..|:|:..|...|   |.:.||.|
plant   295 EKNDGCNHMTCSAP-CGHEFCWICLKAYRRHSG---ACNRFVVEQAESKRALLQ---SEIKRYTH 352

  Fly   369 YYNRY----SNHMQSLKMENKLYSNIQAKMDDMQEEMSWIEVQFLRDAVDVLCQCRTTLMYSYVF 429
            ||.|:    |:.:::::...||.| :|.|.....:..|..::||..||...:.:||..|.::|.:
plant   353 YYVRWAENQSSRLKAMRDLEKLQS-VQLKELSDNQCTSETQLQFTVDAWLQIIECRRVLKWTYAY 416

  Fly   430 AFYLMNNNQKIIFEDNQKDMEMATEKLSECLEREI 464
            .:||.:..::..||..|.:.|...|:|..|.|.|:
plant   417 GYYLQDLPKRKFFEYLQGEAESGLERLHHCAENEL 451

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12362	NP_648392.1	IBR	208..269	CDD:214763	22/62 (35%)
CG12362	NP_648392.1	IBR	273..331	CDD:279784	28/57 (49%)
ARI9	NP_180736.1	RING-HC_RBR_TRIAD1_like	128..178	CDD:319537	18/49 (37%)
		IBR	197..260	CDD:214763	22/62 (35%)
		IBR	<282..326	CDD:396187	22/44 (50%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	76	1.000	Domainoid score	I3141
eggNOG	1	0.900	-	-		E1_KOG1815
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	252	1.000	Inparanoid score	I1022
OMA	1	1.010	-	-		QHG54219
OrthoDB	1	1.010	-	-		D469819at2759
OrthoFinder	1	1.000	-	-		FOG0000379
OrthoInspector	1	1.000	-	-		mtm1045
orthoMCL	1	0.900	-	-		OOG6_100963
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1756
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	11	10.740