Protein Alignment CG12362 and ARI2

DIOPT Version :10

• Sequence 1: NP_648392.1
• Gene: CG12362 / 39193
• FlyBaseID: FBgn0036082
• Length: 511
• Species: Drosophila melanogaster
• Sequence 2: NP_179206.2
• Gene: ARI2 / 816106
• AraportID: AT2G16090
• Length: 593
• Species: Arabidopsis thaliana
• Alignment Length: 533
• Identity: 160/533 - (30%)
• Similarity: 262/533 - (49%)
• Gaps: 66/533 - (12%)

  Fly     1 MNSEMEFSDED--HGDSHRSLLTHMSCENDSDSEDTCTEILLPENSNSPETEDFVYKVLSVDQIV 63
            |:..:...:||  :.....||       |..|::::   :.:|.:|.|.     ..||::.:.::
plant     1 MDDNLSGEEEDYYYSSDQESL-------NGIDNDES---VSIPVSSRSN-----TVKVITKESLL 50

  Fly    64 QHQRNIIDEVNNVLNLPPQVTRIILNHFKWDKESLFENYFESNPKDFFQRAHVLNPFEKKIERES 128
            ..||..:..|..:|::.....|.:|.|::||.|.||....|......|..|.|     ..:|.:|
plant    51 AAQREDLRRVMELLSVKEHHARTLLIHYRWDVEKLFAVLVEKGKDSLFSGAGV-----TLLENQS 110

  Fly   129 AASTSCAIPQL--CGICFCSCD--ELIGLGCGHNFCAACWKQYLANKTCSEGLANTIKCPAANCE 189
            ..|:......:  |.||.....  :|..:.|||:||..||..:...| .:||.:..|.|.|..|.
plant   111 CDSSVSGSSSMMSCDICVEDVPGYQLTRMDCGHSFCNNCWTGHFTVK-INEGQSKRIICMAHKCN 174

  Fly   190 ILV--DYISFLKLADDSEVVERYQQLITNTFVECNMLMRWCPA-PNCSHAVKAVCAEPRAVLCKC 251
            .:.  |.:..|......::.|::.:.:..:::|.|.:::|||: |:|.:|::....|...|.|.|
plant   175 AICDEDVVRALVSKSQPDLAEKFDRFLLESYIEDNKMVKWCPSTPHCGNAIRVEDDELCEVECSC 239

  Fly   252 GHEFCFACGENWHEPASCSSLKKWVKKCLEDSETSNWIAQNTKECPKCNVTIEKDGGCNHMVCKN 316
            |.:|||:|....|.|.||...:.|.|||.::|||.|||..:||.||||:..:||:||||.:.|
plant   240 GLQFCFSCSSQAHSPCSCVMWELWRKKCFDESETVNWITVHTKPCPKCHKPVEKNGGCNLVTC-- 302

  Fly   317 PSCRYDFCWVCLGSWEPHGSSW-----YSCNRFDEEEAKQARLAQQKYRSSMARYLHYYNRYSNH 376
             .||..|||:| |.......:|     :||.||.|::.||    .::.:..:.||:||:|||..|
plant   303 -LCRQSFCWLC-GEATGRDHTWARISGHSCGRFQEDKEKQ----MERAKRDLKRYMHYHNRYKAH 361

  Fly   377 MQSLKMENKLYSNIQAKMD-DMQEEMSWIEVQFLRDAVDVLCQCRTTLMYSYVFAFYL------- 433
            :.|.|:|.||.:||..|:. ..:.|:...:..:..:.:..|.:.|..|.|||.||||:
plant   362 IDSSKLEAKLSNNISKKVSISEKRELQLKDFSWATNGLHRLFRSRRVLSYSYPFAFYMFGDELFK 426

  Fly   434 --MNNNQKII----FEDNQKDMEMATEKLSECLER---EITVKNIYEVKQKVLDLSHYCQKRRHV 489
              |::.::.|    |||.|:.:|...||||:.||.   :.....:.:::.:|::||....
plant   427 DEMSSEEREIKQNLFEDQQQQLEANVEKLSKFLEEPFDQFADDKVMQIRIQVINLSVAVD----- 486

  Fly   490 LLC-HVREGYEND 501
            .|| ::.|..|||
plant   487 TLCENMYECIEND 499

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12362	NP_648392.1	RING-HC_RBR_HHARI	138..194	CDD:438288	18/61 (30%)
		BRcat_RBR_HHARI-like	203..284	CDD:439004	26/81 (32%)
		Rcat_RBR_HHARI-like	288..345	CDD:439017	26/61 (43%)
		Ariadne	346..>480	CDD:466073	44/150 (29%)
ARI2	NP_179206.2	RING-HC_RBR_TRIAD1	126..175	CDD:438429	17/49 (35%)
		BRcat_RBR_ANKIB1	202..266	CDD:439007	22/63 (35%)
		Rcat_RBR_ARI1-like	278..331	CDD:439037	22/56 (39%)
		Ariadne	334..592	CDD:466073	52/175 (30%)