DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG12362 and shrprbck1r

DIOPT Version :9

Sequence 1:NP_648392.1 Gene:CG12362 / 39193 FlyBaseID:FBgn0036082 Length:511 Species:Drosophila melanogaster
Sequence 2:NP_001104670.1 Gene:shrprbck1r / 569903 ZFINID:ZDB-GENE-080220-52 Length:714 Species:Danio rerio


Alignment Length:405 Identity:84/405 - (20%)
Similarity:131/405 - (32%) Gaps:146/405 - (36%)


- Green bases have known domain annotations that are detailed below.


  Fly     1 MNSEMEFSDEDHGDSHRSLLTHMSCENDSDSEDTCTEILLPE-------NSNSPETEDFVYKVLS 58
            :|.|:...:|..|.:..|:....:|       .|||.|..|.       :::.||.    |.|..
Zfish   379 INLELPQLNEALGPNRTSIQPGWAC-------PTCTYINKPTRPGCEMCSADRPEG----YTVPG 432

  Fly    59 VDQIVQHQRNIIDEVNNVLNLPPQVTRIILNHFKWDKESL--FENYFESNPKDFFQR-----AHV 116
                               |..|..  :.|...:.:||::  ::...|:..::.|.|     ...
Zfish   433 -------------------NYRPDA--LELRRIQQEKEAIRQYQQARETERRENFARLVQMDGQD 476

  Fly   117 LNPFEKKIERESAASTSCAIPQLCGICFCSCDELIGL---GCGHNFCAACWKQYLANKTCSEGLA 178
            |.|..:::|              |.||:...:...|:   .|.|.||..|.:..:......:   
Zfish   477 LVPNPERVE--------------CRICYVELESGEGVLLRECLHCFCKECLRSVILMSEDPQ--- 524

  Fly   179 NTIKCP------AANCEILVDYISFLKLADDSEVVERYQQLITN---------------TFVECN 222
              :.||      |.:|.:....|..|...||      ||..:..               ...:| 
Zfish   525 --VACPYRDESYACDCVLQEREIRALVSVDD------YQHWLQRGLSVAESRCEGSYHCATADC- 580

  Fly   223 MLMRWC---PAPNCSHAVKAVCAEPRAVLCKCGHEFCFACGENWHEPASCSSLKKWVKKCLEDSE 284
              ..||   ...|..|.  .||.:...:|||..||     |.|      |        |..:|..
Zfish   581 --PGWCVYEDTVNTFHC--PVCKKQNCLLCKAIHE-----GMN------C--------KQYQDDL 622

  Fly   285 TSNWI----AQNTKE-------------CPKCNVTIEKDGGCNHMVCKNPSCRYDFCWVCLG-SW 331
            |:..|    |:.|::             ||:|.:.::|..||:.:.|  ..|..:.|||..| .|
Zfish   623 TARAINDSAARRTRDLLKTLVNSGEAMHCPQCGIIVQKKEGCDWLRC--TVCHTEICWVTRGPRW 685

  Fly   332 EPHG----SSWYSCN 342
            .|.|    |....||
Zfish   686 GPKGPGDISGGCRCN 700

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG12362NP_648392.1 IBR 208..269 CDD:214763 16/78 (21%)
IBR 273..331 CDD:279784 18/75 (24%)
shrprbck1rNP_001104670.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..23
Sharpin_PH 28..149 CDD:293369
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 152..172
UBQ 225..298 CDD:294102
RanBP2-type Zn finger 401..420 CDD:275376 6/25 (24%)
H4 411..534 CDD:304892 27/166 (16%)
TRIAD supradomain. /evidence=ECO:0000255|PROSITE-ProRule:PRU01221 482..710 59/270 (22%)
IBR 638..678 CDD:279784 8/41 (20%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1815
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
10.900

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