DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12362 and rnf19a

DIOPT Version :9

Sequence 1:	NP_648392.1	Gene:	CG12362 / 39193	FlyBaseID:	FBgn0036082	Length:	511	Species:	Drosophila melanogaster
Sequence 2:	NP_001313624.1	Gene:	rnf19a / 557995	ZFINID:	ZDB-GENE-030131-9414	Length:	913	Species:	Danio rerio

Alignment Length:	354	Identity:	94/354 - (26%)
Similarity:	144/354 - (40%)	Gaps:	85/354 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    41 PENSNSPE-----TEDFVYKVLSVDQIVQHQ------RNIIDEVNNVLNLP-----PQVTRIILN 89
            |.:|:||.     ::.|.....|..::..||      |::....::| :||     |:..||.|
Zfish    66 PSSSSSPSLPVDTSQSFGNHSASFGEMSLHQQQQGSERDLPSAASSV-SLPSVRKTPKKRRISL- 128

  Fly    90 HFKWDKESLFENYFESNPKDFFQR---------AHVLNPFEKKIERESAASTSCAIPQLCGICF- 144
                  .|||.... .:||....|         |.|.:...:..:::..||...|    .|:.:
Zfish   129 ------RSLFRRRC-GDPKSRKSRALAAGVDGIASVESVHSEMCQQQDHASALSA----AGVAYT 182

  Fly   145 -CSCDELIG-----------------------LGCGHNFCAACWKQYLANKTCSEGLANTIKCPA 185
             .||....|                       :.|.|..||.|.:|||..: .||...| |.||
Zfish   183 SSSCSSSSGSTSELLECPLCLLRHTRDRFPDIMTCHHRSCADCLRQYLRIE-ISESRVN-ISCP- 244

  Fly   186 ANCEILVDYISFLKLADDSEVVERYQQLITNTFVECNMLMRWCPAPNCSHAVKAV-CAEPRAVLC 249
             .|....:......:.:|..::|:|::.:...::..:...||||||:|.:||.|. ||....:.|
Zfish   245 -ECSERFNPHDIRMILNDRVLMEKYEEFMLRRWLVADPDCRWCPAPDCGYAVIAFGCASCPKITC 308

  Fly   250 ---KCGHEFCFACGENWHEPASCSS----------LKKWVKKCLEDSETSNWIAQNTKECPKCNV 301
               .||.|||:.|.:.||...:|.:          |:.:....|..|:.|...|.:.|.||:|..
Zfish   309 GRDGCGTEFCYHCKQLWHPNQTCDAARQQRAQSLRLRPFRSSSLSYSQESGAAADDIKPCPRCAA 373

  Fly   302 TIEK--DGGCNHMVCKNPSCRYDFCWVCL 328
            .|.|  ||.||||.|  ..|..:|||:|:
Zfish   374 YIIKMNDGSCNHMTC--AVCGCEFCWLCM 400

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12362	NP_648392.1	IBR	208..269	CDD:214763	23/64 (36%)
CG12362	NP_648392.1	IBR	273..331	CDD:279784	22/58 (38%)
rnf19a	NP_001313624.1	IBR	266..331	CDD:214763	23/64 (36%)
		IBR	<364..402	CDD:279784	18/39 (46%)
		AzlC	<428..517	CDD:294385
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1815
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810