DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG12362 and rbck1

DIOPT Version :9

Sequence 1:	NP_648392.1	Gene:	CG12362 / 39193	FlyBaseID:	FBgn0036082	Length:	511	Species:	Drosophila melanogaster
Sequence 2:	NP_001002168.1	Gene:	rbck1 / 431715	ZFINID:	ZDB-GENE-040704-3	Length:	515	Species:	Danio rerio

Alignment Length:	270	Identity:	59/270 - (21%)
Similarity:	105/270 - (38%)	Gaps:	61/270 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   100 ENYFESNPKDFFQRAHVLNPFEKKIERESAASTSCAIPQLCGICFCSCDELIGLG-----CGHNF 159
            ::..:...::|.:|.   ..:|:.::.::.:.........|.|||.:.  :.|.|     |.|:|
Zfish   250 QSLLQEEERNFLERQ---RNYEELLQTDAHSLVGNTDQLECAICFGTI--MPGEGAVLRECLHSF 309

  Fly   160 CAACWKQYLANKTCSEGLANTIKCP------AANCEILVDYISFLKLADDSEVVERYQQLITNTF 218
            |..|.|..:.|...:|     :.||      |.||::....|..|...|:   .:::.:|..|..
Zfish   310 CRDCLKGTVVNCLDAE-----VCCPYGDNAYACNCKLQDREIKSLLTQDE---YQKFLELRLNIA 366

  Fly   219 VECNMLMRWCPAPNCS---------HAVKA-VCAEPRAVLCKCGHEFCFACGENWHE-------- 265
            ...:.....|..|:|:         :..|. :|.|...:|||..|:     |.|..|
Zfish   367 ESRSENSYHCKTPDCAGWCIFEDDVNEFKCDICNETNCLLCKAIHK-----GMNCKEYQDDLRVR 426

  Fly   266 ---PASCSSLKKWVKKCLEDSETSNWIAQNTKECPKCNVTIEKDGGCNHMVCKNPSCRYDFCWVC 327
               ..:.....:.:.:.|::.|..|        ||||.|.::|..||:.:.|.  .|:.:.|||.
Zfish   427 AQNDEAARQTTEMLDQLLKNGEAMN--------CPKCQVIVQKKDGCDWICCL--MCKTEICWVT 481

  Fly   328 -LGSWEPHGS 336
             ...|.|.|:
Zfish   482 KQARWGPLGA 491

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12362	NP_648392.1	IBR	208..269	CDD:214763	15/81 (19%)
CG12362	NP_648392.1	IBR	273..331	CDD:279784	16/58 (28%)
rbck1	NP_001002168.1	UBQ	62..136	CDD:320785
		RanBP2-type Zn finger	195..214	CDD:275376
		RING_Ubox	283..337	CDD:327409	16/60 (27%)
		IBR	356..409	CDD:307574	10/52 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1815
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900