Protein Alignment CG12362 and arih1l

DIOPT Version :10

• Sequence 1: NP_648392.1
• Gene: CG12362 / 39193
• FlyBaseID: FBgn0036082
• Length: 511
• Species: Drosophila melanogaster
• Sequence 2: NP_998088.1
• Gene: arih1l / 405859
• ZFINID: ZDB-GENE-040426-2395
• Length: 533
• Species: Danio rerio
• Alignment Length: 531
• Identity: 277/531 - (52%)
• Similarity: 356/531 - (67%)
• Gaps: 35/531 - (6%)

  Fly     6 EFSDEDHGDSHRSLLTHMSCENDSDSEDTC--------TEILLP------------ENSNSP--- 47
            ||.||:..:....     .|..||..|:..        .|:|.|            .....|
Zfish    10 EFDDEEEEEEEEE-----ECSVDSGEEEAVDDSLELGEVELLDPAVAGGEPDDCADTGGGGPGPG 69

  Fly    48 -ETEDFVYKVLSVDQIVQHQRNIIDEVNNVLNLPPQVTRIILNHFKWDKESLFENYFESNPKDFF 111
             |.||:.::||:.:||:||....|.:||.|:..|..:|||:|:||.||||.|.|.||:.|....|
Zfish    70 QEDEDYRFEVLTTEQILQHMVECIRDVNEVIQNPATITRILLSHFNWDKEKLMERYFDGNLDKLF 134

  Fly   112 QRAHVLNPFEK-KIERESAASTSCAIPQLCGICFCSCDE--LIGLGCGHNFCAACWKQYLANKTC 173
            ...||:||.:| |....|..|:|..:|  |.||:.:...  ..||.|||.||..||..||..|..
Zfish   135 SECHVINPSKKPKTRPMSTRSSSQDLP--CQICYLNYPNSYFTGLECGHKFCMQCWGDYLTTKII 197

  Fly   174 SEGLANTIKCPAANCEILVDYISFLKLADDSEVVERYQQLITNTFVECNMLMRWCPAPNCSHAVK 238
            .||:..||.|||.||:||||..:.::|..||:|..:||.||||:|||||.|::|||||:|.|.||
Zfish   198 EEGMGQTISCPAHNCDILVDDNTVMRLITDSKVKLKYQHLITNSFVECNRLLKWCPAPDCHHVVK 262

  Fly   239 AVCAEPRAVLCKCGHEFCFACGENWHEPASCSSLKKWVKKCLEDSETSNWIAQNTKECPKCNVTI 303
            ....:.:.|.||||.:|||.||||||:|..|..|:||:|||.:|||||||||.||||||||:|||
Zfish   263 VQYPDAKPVRCKCGRQFCFNCGENWHDPVKCKWLRKWIKKCDDDSETSNWIAANTKECPKCHVTI 327

  Fly   304 EKDGGCNHMVCKNPSCRYDFCWVCLGSWEPHGSSWYSCNRFDEEEAKQARLAQQKYRSSMARYLH 368
            |||||||||||:|.:|:.:|||||||.||||||:||:|||::|::||.||.||::.|:::.|||.
Zfish   328 EKDGGCNHMVCRNQNCKAEFCWVCLGPWEPHGSAWYNCNRYNEDDAKAARDAQERSRAALQRYLF 392

  Fly   369 YYNRYSNHMQSLKMENKLYSNIQAKMDDMQE-EMSWIEVQFLRDAVDVLCQCRTTLMYSYVFAFY 432
            |.|||.||||||:.|:|||:.::.||::||: .|||||||||:.|||||||||:|||::||||||
Zfish   393 YCNRYMNHMQSLRFEHKLYAQVKQKMEEMQQHNMSWIEVQFLKKAVDVLCQCRSTLMFTYVFAFY 457

  Fly   433 LMNNNQKIIFEDNQKDMEMATEKLSECLEREITVKNIYEVKQKVLDLSHYCQKRRHVLLCHVREG 497
            |..|||.||||:||.|:|.|||.||..|||:|:..::.::||||.|...||:.||.|||.||.||
Zfish   458 LKKNNQSIIFENNQADLENATEVLSGYLERDISQDSLQDIKQKVQDKYRYCESRRRVLLQHVHEG 522

  Fly   498 YENDWWEFKEE 508
            ||.|.||:.|:
Zfish   523 YEKDLWEYIED 533

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12362	NP_648392.1	RING-HC_RBR_HHARI	138..194	CDD:438288	27/57 (47%)
		BRcat_RBR_HHARI-like	203..284	CDD:439004	47/80 (59%)
		Rcat_RBR_HHARI-like	288..345	CDD:439017	45/56 (80%)
		Ariadne	346..>480	CDD:466073	82/134 (61%)
arih1l	NP_998088.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..35		8/29 (28%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	48..73		3/24 (13%)
		TRIAD supradomain. /evidence=ECO:0000255|PROSITE-ProRule:PRU01221	158..369		127/212 (60%)
		RING-HC_RBR_HHARI	160..218	CDD:438288	28/59 (47%)
		BRcat_RBR_HHARI-like	227..308	CDD:439004	47/80 (59%)
		Rcat_RBR_HHARI-like	312..369	CDD:439017	45/56 (80%)
		Ariadne	370..>501	CDD:466073	79/130 (61%)