Protein Alignment CG12362 and ari-2

DIOPT Version :10

• Sequence 1: NP_648392.1
• Gene: CG12362 / 39193
• FlyBaseID: FBgn0036082
• Length: 511
• Species: Drosophila melanogaster
• Sequence 2: NP_477374.1
• Gene: ari-2 / 37542
• FlyBaseID: FBgn0025186
• Length: 509
• Species: Drosophila melanogaster
• Alignment Length: 526
• Identity: 165/526 - (31%)
• Similarity: 272/526 - (51%)
• Gaps: 60/526 - (11%)

  Fly     1 MNSEMEFSDEDHGDSHRSLLTHMSCENDSD------SEDTCTEILLPENSNSPETEDFVYKVLSV 59
            |:|::|...|...|.          |.|.|      .||...|.|.|:.:   :.|.|.|:.|:|
  Fly     1 MDSDIEMDMESDNDG----------EYDDDYDYYNTGEDCDVERLDPKRA---DPEYFEYECLTV 52

  Fly    60 DQIVQHQRNIIDEVNNVLNLPPQVTRIILNHFKWDKESLFENYFESNPKDFFQRAHVLNPFEKKI 124
            :.|.:.....::::|.:|.:.|.:.:::|...:|:..::.|.| ..:.......|.:..|   .:
  Fly    53 EDIEKLLNERVEKLNTILQITPSLAKVLLLEHQWNNVAVVEKY-RQDANALLVTARIKPP---SV 113

  Fly   125 ERESAASTSCAI------------------------PQLCGICFCS--CDELIGLGCGHNFCAAC 163
            .....||||.|.                        .|:|.:|..|  .|:...|.|||:||..|
  Fly   114 AVTDTASTSAAAASAQLLRLGSSGYKTTASATPQYRSQMCPVCASSQLGDKFYSLACGHSFCKDC 178

  Fly   164 WKQYLANKTCSEGLANTIKCPAANCEILVDYISFLKLADDSEVVERYQQLITNTFVECNMLMRWC 228
            |..|...: ..:|::..|.|.|..|.:.|.....|.|.....:.::|||.....:|:.:..:|:|
  Fly   179 WTIYFETQ-IFQGISTQIGCMAQMCNVRVPEDLVLTLVTRPVMRDKYQQFAFKDYVKSHPELRFC 242

  Fly   229 PAPNCSHAVKAVCAEPRAVLCKCGHE-FCFACGENWHEPASCSSLKKWVKKCLEDSETSNWIAQN 292
            |.|||...|::.....:..:||..|. |||.||.::|.|..|..:|||:.||.:||||:|:|:.:
  Fly   243 PGPNCQIIVQSSEISAKRAICKACHTGFCFRCGMDYHAPTDCQVIKKWLTKCADDSETANYISAH 307

  Fly   293 TKECPKCNVTIEKDGGCNHMVCKNPSCRYDFCWVCLGSWEPHGSSWYSCNRFDEEEAKQARLAQQ 357
            ||:||||::.|||:||||||.|.|  |::||||:|||.|:.|||.:|.|:|:.:...........
  Fly   308 TKDCPKCHICIEKNGGCNHMQCFN--CKHDFCWMCLGDWKTHGSEYYECSRYKDNPNIANESVHV 370

  Fly   358 KYRSSMARYLHYYNRYSNHMQSLKMENKLYSNIQAKMDD--MQEEMSWIEVQFLRDAVDVLCQCR 420
            :.|.::.:|||||.|:.||.:|||:|.:....::.:::.  |....:||:.|:|.:|..:|.:||
  Fly   371 QAREALKKYLHYYERWENHSKSLKLEQQTIDRLRQRINSKVMNGSGTWIDWQYLFNAAALLAKCR 435

  Fly   421 TTLMYSYVFAFYLMNNNQKIIFEDNQKDMEMATEKLSECLEREITVKNIYEVKQKVLDLSHYCQK 485
            .||.|:|.:|:|:...::|.:||..|..:|...|.||..:||..|. ::.:::.: :|::   :|
  Fly   436 YTLQYTYPYAYYMEAGSRKNLFEYQQAQLEAEIENLSWKIERAETT-DLGDLENQ-MDIA---EK 495

  Fly   486 RRHVLL 491
            ||..||
  Fly   496 RRTTLL 501

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12362	NP_648392.1	RING-HC_RBR_HHARI	138..194	CDD:438288	20/57 (35%)
		BRcat_RBR_HHARI-like	203..284	CDD:439004	28/81 (35%)
		Rcat_RBR_HHARI-like	288..345	CDD:439017	33/56 (59%)
		Ariadne	346..>480	CDD:466073	40/135 (30%)
ari-2	NP_477374.1	RING-HC_RBR_TRIAD1	152..204	CDD:438429	18/52 (35%)
		BRcat_RBR_TRIAD1	231..302	CDD:439005	28/70 (40%)
		Rcat_RBR_TRIAD1	306..361	CDD:439021	32/56 (57%)
		Ariadne	371..>477	CDD:466073	36/105 (34%)