Protein Alignment CG12362 and ari-1

DIOPT Version :10

• Sequence 1: NP_648392.1
• Gene: CG12362 / 39193
• FlyBaseID: FBgn0036082
• Length: 511
• Species: Drosophila melanogaster
• Sequence 2: NP_523399.1
• Gene: ari-1 / 32796
• FlyBaseID: FBgn0017418
• Length: 503
• Species: Drosophila melanogaster
• Alignment Length: 513
• Identity: 306/513 - (59%)
• Similarity: 387/513 - (75%)
• Gaps: 16/513 - (3%)

  Fly     1 MNSEMEFSDEDHGDSHRSLLTHMSCENDSDSEDTCTEILLPENSN-SPETEDFVYKVLSVDQIVQ 64
            |:|:   :|.|..|:..|  .::|..:|.| :|...|:.||.::: ..:.:|:.||||:.|:|||
  Fly     1 MDSD---NDNDFCDNVDS--GNVSSGDDGD-DDFGMEVDLPSSADRQMDQDDYQYKVLTTDEIVQ 59

  Fly    65 HQRNIIDEVNNVLNLPPQVTRIILNHFKWDKESLFENYFESNPKDFFQRAHVLNPFE--KKIERE 127
            |||.||||.|.:|.||...|||:|||||||||.|.|.||:.|..:||:.|||:|||.  :.|:::
  Fly    60 HQREIIDEANLLLKLPTPTTRILLNHFKWDKEKLLEKYFDDNTDEFFKCAHVINPFNATEAIKQK 124

  Fly   128 SAASTSCAIPQLCGICFCSC--DELIGLGCGHNFCAACWKQYLANKTCSEGLANTIKCPAANCEI 190
            ::.| .|   :.|.|||...  |.:.||.|||.||..||.:||:.|..:|||..||.|.|..|:|
  Fly   125 TSRS-QC---EECEICFSQLPPDSMAGLECGHRFCMPCWHEYLSTKIVAEGLGQTISCAAHGCDI 185

  Fly   191 LVDYISFLKLADDSEVVERYQQLITNTFVECNMLMRWCPAPNCSHAVKAVCAEPRAVLCKCGHEF 255
            |||.::...|..|:.|..:|||||||:|||||.|:||||:.:|::|||...||||.|.|||||.|
  Fly   186 LVDDVTVANLVTDARVRVKYQQLITNSFVECNQLLRWCPSVDCTYAVKVPYAEPRRVHCKCGHVF 250

  Fly   256 CFACGENWHEPASCSSLKKWVKKCLEDSETSNWIAQNTKECPKCNVTIEKDGGCNHMVCKNPSCR 320
            |||||||||:|..|..||||:|||.:|||||||||.||||||:|:||||||||||||||||.:|:
  Fly   251 CFACGENWHDPVKCRWLKKWIKKCDDDSETSNWIAANTKECPRCSVTIEKDGGCNHMVCKNQNCK 315

  Fly   321 YDFCWVCLGSWEPHGSSWYSCNRFDEEEAKQARLAQQKYRSSMARYLHYYNRYSNHMQSLKMENK 385
            .:|||||||||||||||||:|||:||:|||.||.||:|.|||:||||||||||.|||||:|.|||
  Fly   316 NEFCWVCLGSWEPHGSSWYNCNRYDEDEAKTARDAQEKLRSSLARYLHYYNRYMNHMQSMKFENK 380

  Fly   386 LYSNIQAKMDDMQE-EMSWIEVQFLRDAVDVLCQCRTTLMYSYVFAFYLMNNNQKIIFEDNQKDM 449
            ||::::.||::||: .|||||||||:.|||:|||||.||||:||||:||..|||.:||||||||:
  Fly   381 LYASVKQKMEEMQQHNMSWIEVQFLKKAVDILCQCRQTLMYTYVFAYYLKKNNQSMIFEDNQKDL 445

  Fly   450 EMATEKLSECLEREITVKNIYEVKQKVLDLSHYCQKRRHVLLCHVREGYENDWWEFKE 507
            |.|||.|||.|||:||.:|:.::||||.|...||:||..|||.||.|||:.:|||:.|
  Fly   446 ESATEMLSEYLERDITSENLADIKQKVQDKYRYCEKRCSVLLKHVHEGYDKEWWEYTE 503

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12362	NP_648392.1	RING-HC_RBR_HHARI	138..194	CDD:438288	28/57 (49%)
		BRcat_RBR_HHARI-like	203..284	CDD:439004	53/80 (66%)
		Rcat_RBR_HHARI-like	288..345	CDD:439017	47/56 (84%)
		Ariadne	346..>480	CDD:466073	93/134 (69%)
ari-1	NP_523399.1	RING-HC_RBR_HHARI	131..189	CDD:438288	28/57 (49%)
		BRcat_RBR_HHARI-like	198..279	CDD:439004	53/80 (66%)
		Rcat_RBR_HHARI-like	283..340	CDD:439017	47/56 (84%)
		Ariadne	341..>459	CDD:466073	84/117 (72%)