Protein Alignment CG12362 and RNF144B

DIOPT Version :10

• Sequence 1: NP_648392.1
• Gene: CG12362 / 39193
• FlyBaseID: FBgn0036082
• Length: 511
• Species: Drosophila melanogaster
• Sequence 2: NP_877434.2
• Gene: RNF144B / 255488
• HGNCID: 21578
• Length: 303
• Species: Homo sapiens
• Alignment Length: 210
• Identity: 67/210 - (31%)
• Similarity: 92/210 - (43%)
• Gaps: 37/210 - (17%)

  Fly   140 CGICFC--SCDELIGL-GCGHNFCAACWKQYLANKTCSEGLANTIKCPAANC----EILVDYISF 197
            |.:|.|  |.|::..| .|...||.||.|||: .....||..:.|.||...|    .:....|:.
Human    30 CKLCLCEQSLDKMTTLQECQCIFCTACLKQYM-QLAIREGCGSPITCPDMVCLNHGTLQEAEIAC 93

  Fly   198 LKLADDSEVVERYQQLITNTFVECNMLMRWCPAPNCSHAVKAVC-------AEPRAVLC-KCGHE 254
            |...|..::   ||:|.....|..:....|||..:|    :.||       .:|..|.| .|..:
Human    94 LVPVDQFQL---YQRLKFEREVHLDPYRTWCPVADC----QTVCPVASSDPGQPVLVECPSCHLK 151

  Fly   255 FCFACGENWHEPASCSSLKKWV----KKCL--EDSETSNWIAQNTKECPKCNVTIEKDGGCNHMV 313
            ||..|.:.||...||...:..|    .:.|  .|:|..      .|:||.|.|.||::.||..|:
Human   152 FCSCCKDAWHAEVSCRDSQPIVLPTEHRALFGTDAEAP------IKQCPVCRVYIERNEGCAQMM 210

  Fly   314 CKNPSCRYDFCWVCL 328
            |||  |::.|||.||
Human   211 CKN--CKHTFCWYCL 223

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12362	NP_648392.1	RING-HC_RBR_HHARI	138..194	CDD:438288	20/60 (33%)
		BRcat_RBR_HHARI-like	203..284	CDD:439004	24/94 (26%)
		Rcat_RBR_HHARI-like	288..345	CDD:439017	19/41 (46%)
		Ariadne	346..>480	CDD:466073
RNF144B	NP_877434.2	TRIAD supradomain. /evidence=ECO:0000255|PROSITE-ProRule:PRU01221	26..244		67/210 (32%)
		mRING-HC-C4C4_RBR_RNF144B	28..84	CDD:438434	20/54 (37%)
		BRcat_RBR_RNF144B	111..174	CDD:439028	18/66 (27%)
		Rcat_RBR_RNF144B	185..255	CDD:439030	21/47 (45%)