DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG12362 and SPAC328.02

DIOPT Version :9

Sequence 1:	NP_648392.1	Gene:	CG12362 / 39193	FlyBaseID:	FBgn0036082	Length:	511	Species:	Drosophila melanogaster
Sequence 2:	NP_594204.1	Gene:	SPAC328.02 / 2543148	PomBaseID:	SPAC328.02	Length:	504	Species:	Schizosaccharomyces pombe

Alignment Length:	511	Identity:	205/511 - (40%)
Similarity:	301/511 - (58%)	Gaps:	29/511 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 EFSDEDHGDSHRSLLTHMSCENDSDSEDTCTEILLPENSNSPETEDFVYKVLSVDQIVQHQRNII 70
            ||.:|:.   ...||.....|::.|.:....:................|:|:||..:.......|
pombe     8 EFYEEEF---ENDLLDASEFEDEFDEDAEIDDDGFTVERKRRRAHSVSYRVVSVRDLRASLNEKI 69

  Fly    71 DEVNNVLNLPPQVTRIILNHFKWDKESLFENYFESNPKDFFQRAHVLNPFEKKIERESAASTSCA 135
            :::.::::|..:....:..:|||::|.|.|.|.:: |::..|:|.|.....|:.|......|
pombe    70 NQLTSIIDLTREQVLGLYRYFKWNRERLLERYIDA-PEESLQKAGVGLSGSKQREVVHHEGT--- 130

  Fly   136 IPQLCGICFC-SCDELIGLGCGHNFCAACWKQYLANKTCSEGLANTIKCPAANCEILVDYISFLK 199
                |.||:. .|.......|.|.||.||::|||.:: .||| .:.|:||..:|..:|...|..|
pombe   131 ----CEICYDEGCLPFFSAECDHEFCLACYRQYLDSR-ISEG-ESVIQCPEESCTQIVSIQSITK 189

  Fly   200 LADDSEVVERYQQLITNTFVECNMLMRWCPAPNCSHAVKAVCAEPRA--------VLCKCGHEFC 256
            :.|:.. ::||.:|:..:||:.|..:||||||:|..|::  |...:|        |.|.||.:||
pombe   190 VLDEKS-LDRYHRLLDRSFVDDNDHLRWCPAPDCEFAIE--CHVTQASLSSVVPTVTCNCGKQFC 251

  Fly   257 FACGENWHEPASCSSLKKWVKKCLEDSETSNWIAQNTKECPKCNVTIEKDGGCNHMVCKNPSCRY 321
            |.||.:.|:|..|..:|.|::||.:||||:|||..||||||||:.||||:||||||.||  .|:|
pombe   252 FGCGHDNHQPTICPLVKIWLQKCQDDSETANWIHANTKECPKCSTTIEKNGGCNHMTCK--KCKY 314

  Fly   322 DFCWVCLGSWEPHGSSWYSCNRFDEEEAKQARLAQQKYRSSMARYLHYYNRYSNHMQSLKMENKL 386
            :|||||||.|..||::||:|||::|:.:..||.:|.|.|:|:.||||||||::||.||.|::::|
pombe   315 EFCWVCLGPWTEHGNNWYTCNRYEEKSSTSARDSQSKSRASLERYLHYYNRFANHEQSAKLDHEL 379

  Fly   387 YSNIQAKMDDMQ--EEMSWIEVQFLRDAVDVLCQCRTTLMYSYVFAFYLMNNNQKIIFEDNQKDM 449
            |.:...:|..||  ..:||:|||||::|||:|.|||.||.::|.||:||..|||..||||||:|:
pombe   380 YEHTHKRMTQMQVDSNLSWVEVQFLKNAVDILFQCRQTLKWTYAFAYYLARNNQTEIFEDNQRDL 444

  Fly   450 EMATEKLSECLEREITVKNIYEVKQKVLDLSHYCQKRRHVLLCHVREGYENDWWEF 505
            |:|.|.|||..||.....::...||:|||.:.|.:.||.|||.....|.....||:
pombe   445 ELAVENLSELCERPCQDCSLSVFKQRVLDKTVYVRSRRDVLLDDTARGLAEGRWEY 500

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12362	NP_648392.1	IBR	208..269	CDD:214763	27/68 (40%)
CG12362	NP_648392.1	IBR	273..331	CDD:279784	40/57 (70%)
SPAC328.02	NP_594204.1	zf-C3HC4	131..175	CDD:278524	18/45 (40%)
		IBR	197..264	CDD:214763	27/68 (40%)
		IBR	<285..324	CDD:279784	29/40 (73%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	189	1.000	Domainoid score	I736
eggNOG	1	0.900	-	-		E1_KOG1815
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	408	1.000	Inparanoid score	I366
OMA	1	1.010	-	-		QHG54219
OrthoFinder	1	1.000	-	-		FOG0000379
OrthoInspector	1	1.000	-	-		otm47105
orthoMCL	1	0.900	-	-		OOG6_100963
Panther	1	1.100	-	-	O	PTHR11685
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	11	10.830