Protein Alignment CG12362 and ari-1.3

DIOPT Version :9

• Sequence 1: NP_648392.1
• Gene: CG12362 / 39193
• FlyBaseID: FBgn0036082
• Length: 511
• Species: Drosophila melanogaster
• Sequence 2: NP_001379539.1
• Gene: ari-1.3 / 172282
• WormBaseID: WBGene00016156
• Length: 491
• Species: Caenorhabditis elegans
• Alignment Length: 520
• Identity: 229/520 - (44%)
• Similarity: 311/520 - (59%)
• Gaps: 42/520 - (8%)

  Fly     1 MNSEMEF------SDEDHGDSHRSLLTHMSCENDSDS----EDTCTEILLPENSNSPETEDFVYK 55
            |||:.|.      |.||..|.        .|.:|.|.    :.:.::.|   |....:.|
 Worm     1 MNSDDEIYMEGSASSEDDMDD--------ECLSDDDGIARHDQSASDYL---NKKDKDNE----- 49

  Fly    56 VLSVDQIVQHQRNIIDEVNNVLNLPPQVTRIILNHFKWDKESLFENYFESNPKD--FFQRAHVLN 118
            ||..|.:....:..|.||..||.:...|.||:|:.:||:||||.|.::| :|..  |...|.|:
 Worm    50 VLDHDSLEAEMKKAISEVEAVLQVKTGVCRILLHKYKWNKESLLERFYE-HPDTIAFLIDAQVI- 112

  Fly   119 PFEKKIERESAASTSCAIPQLCGICFCSCDELIGLGCGHNFCAACWKQYLANKTCSEGLANTIKC 183
            |.::::.....|.        |.|| ||.|||.||.|.|..||.||:.||.||..|:. .:.|:|
 Worm   113 PRQQEVIPAGDAE--------CDIC-CSMDELSGLSCNHRACAECWQAYLTNKIVSDA-QSEIEC 167

  Fly   184 PAANCEILVDYISFLKLADDSEVVERYQQLITNTFVECNMLMRWCPAPNCSHAVKAVCAEPRAVL 248
            .|.||::|::....|....|..:|.:|::|:..::||.|.|:||||..:|..|||....|||.|:
 Worm   168 MAPNCKLLIEDEKVLSYISDPTMVSKYRKLMVASYVEINCLLRWCPGIDCGKAVKVSHWEPRLVV 232

  Fly   249 CKCGHEFCFACGENWHEPASCSSLKKWVKKCLEDSETSNWIAQNTKECPKCNVTIEKDGGCNHMV 313
            |.||..|||:||:|||||.:|..||||:|||.:||||.|||..|||:||||.:.|||:||||.|:
 Worm   233 CSCGTCFCFSCGQNWHEPLNCRHLKKWIKKCQDDSETMNWINANTKDCPKCMIPIEKNGGCNRML 297

  Fly   314 CKNPSCRYDFCWVCLGSWEPHGSSWYSCNRFDEEEAKQARLAQQKYRSSMARYLHYYNRYSNHMQ 378
            |.|..|||:|||:||..|..||.. |:||.:||...|..:.||:..|:::.|||.|:|||..|.|
 Worm   298 CTNSGCRYEFCWMCLEPWTKHGYQ-YACNGYDETAVKNPQDAQEISRANLKRYLFYFNRYMGHEQ 361

  Fly   379 SLKMENKLYSNIQAKMDDMQE-EMSWIEVQFLRDAVDVLCQCRTTLMYSYVFAFYLMNNNQKIIF 442
            ||::|.||...:..||:.|:. .||||||||||.|||:|.:||.||||:|.|||||..:|..|||
 Worm   362 SLQLEGKLNIKVAKKMEQMENMSMSWIEVQFLRKAVDILSECRRTLMYTYAFAFYLKKDNNSIIF 426

  Fly   443 EDNQKDMEMATEKLSECLEREITVKNIYEVKQKVLDLSHYCQKRRHVLLCHVREGYENDWWEFKE 507
            |.||.::||.||:||..|||::..:::..:||||.|...|.::||.|||.|..||.|.|.|::.:
 Worm   427 ESNQANLEMETEQLSGFLERDLEDEDLVTLKQKVQDKYRYVEQRRKVLLDHCAEGAEQDIWQYND 491

  Fly   508  507
             Worm   492  491

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12362	NP_648392.1	IBR	208..269	CDD:214763	31/60 (52%)
		IBR	273..331	CDD:279784	38/57 (67%)
ari-1.3	NP_001379539.1	RING_Ubox	125..178	CDD:418438	27/62 (44%)
		RING-HC finger (C3HC4-type)	126..172	CDD:319361	24/47 (51%)
		IBR	193..253	CDD:214763	31/59 (53%)
		IBR	<274..315	CDD:396187	25/40 (63%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160167539
Domainoid	1	1.000	238	1.000	Domainoid score	I1280
eggNOG	1	0.900	-	-		E1_KOG1815
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	535	1.000	Inparanoid score	I649
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54219
OrthoDB	1	1.010	-	-		D429758at33208
OrthoFinder	1	1.000	-	-		FOG0000379
OrthoInspector	1	1.000	-	-		mtm4735
orthoMCL	1	0.900	-	-		OOG6_100963
Panther	1	1.100	-	-	O	PTHR11685
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	13	12.810