Protein Alignment CG12362 and RNF217

DIOPT Version :10

• Sequence 1: NP_648392.1
• Gene: CG12362 / 39193
• FlyBaseID: FBgn0036082
• Length: 511
• Species: Drosophila melanogaster
• Sequence 2: XP_011533796.1
• Gene: RNF217 / 154214
• HGNCID: 21487
• Length: 567
• Species: Homo sapiens
• Alignment Length: 248
• Identity: 61/248 - (24%)
• Similarity: 87/248 - (35%)
• Gaps: 58/248 - (23%)

  Fly   139 LCGICF-------CSCDELIGLGCGHNFCAACWKQYLANKTCSEGLANTIKCPAANC-EILVDYI 195
            :|.:|.       ..|       |....|..|.|.||:.:. ..|... ||||...| |.|.:..
Human   262 MCRVCLEDKPIKPLPC-------CKKAVCEECLKVYLSAQV-QLGQVE-IKCPITECFEFLEETT 317

  Fly   196 SFLKLADDSEVVERYQQLITNTFVECNML-MRWCPAPNCSHAV----KAVCAEPR------AVLC 249
            ....|..:..:..:|       |:|...: ....|.|.|.|..    |.....|.      .:.|
Human   318 VVYNLTHEDSIKYKY-------FLELGRIDSSTKPCPQCKHFTTFKKKGHIPTPSRSESKYKIQC 375

  Fly   250 -KCGHEFCFACGENWHEPASCSSLKKWVKKCLEDSETSNWIAQ------NTKECPKCNVTIEKDG 307
             .|...:||.|...|||..:|...||      .|....:|.::      |.::||||.:.|::..
Human   376 PTCQFVWCFKCHSPWHEGVNCKEYKK------GDKLLRHWASEIEHGQRNAQKCPKCKIHIQRTE 434

  Fly   308 GCNHMVCKNPSCRYDFCWVCLGSWEPHGSSWYSCNRFDEEEAKQARLAQQKYR 360
            ||:||.|.  .|..:||:.|        ...|...||..:......:...|||
Human   435 GCDHMTCS--QCNTNFCYRC--------GERYRQLRFFGDHTSNLSIFGCKYR 477

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12362	NP_648392.1	RING-HC_RBR_HHARI	138..194	CDD:438288	17/62 (27%)
		BRcat_RBR_HHARI-like	203..284	CDD:439004	21/92 (23%)
		Rcat_RBR_HHARI-like	288..345	CDD:439017	18/62 (29%)
		Ariadne	346..>480	CDD:466073	3/15 (20%)
RNF217	XP_011533796.1	PHA03247	<14..243	CDD:223021
		vRING-HC-C4C4_RBR_RNF217	261..309	CDD:438284	14/55 (25%)
		BRcat_RBR_RNF217	338..412	CDD:439003	19/79 (24%)
		Rcat_RBR_RNF217	416..483	CDD:439011	21/72 (29%)