DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG32055 and GHR1

DIOPT Version :9

Sequence 1:	NP_729599.1	Gene:	CG32055 / 39188	FlyBaseID:	FBgn0052055	Length:	534	Species:	Drosophila melanogaster
Sequence 2:	NP_001320016.1	Gene:	GHR1 / 827842	AraportID:	AT4G20940	Length:	1037	Species:	Arabidopsis thaliana

Alignment Length:	444	Identity:	114/444 - (25%)
Similarity:	176/444 - (39%)	Gaps:	111/444 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   133 DILAITT----KLMSGFGNLVYANFSENLIAVIEPNAFRHMKNLRFLDLTTN-YQENI--TLGEN 190
            |.|.:|.    .|.|....||..:.|.|.::.:.||.....|:|:||||:.| :..::  .:|.:
plant    61 DNLGLTADADFSLFSNLTKLVKLSMSNNSLSGVLPNDLGSFKSLQFLDLSDNLFSSSLPKEIGRS 125

  Fly   191 ANLRFLSISNNN-----------------------------------LRDFQWCHL--------- 211
            .:||.||:|.||                                   |.|..:.:|
plant   126 VSLRNLSLSGNNFSGEIPESMGGLISLQSLDMSSNSLSGPLPKSLTRLNDLLYLNLSSNGFTGKM 190

  Fly   212 ----RVLPKLEELHLHSNWLE-HLDMGIFYALPNLRVLNVSNNNLFEIKRTLFMAPGEIAPLELL 271
                .::..||.|.||.|.:: :|| |.|:.|.|...:::|.|.|......|.  ||....::.|
plant   191 PRGFELISSLEVLDLHGNSIDGNLD-GEFFLLTNASYVDISGNRLVTTSGKLL--PGVSESIKHL 252

  Fly   272 DYSSNIVKVLDDSVFCRLKKLRTLNLWLNQI-------NRIHPRAFLGLSS-------------- 315
            :.|.|.::....|.|...:.|:.|:|..|.:       |.::....|.||:
plant   253 NLSHNQLEGSLTSGFQLFQNLKVLDLSYNMLSGELPGFNYVYDLEVLKLSNNRFSGSLPNNLLKG 317

  Fly   316 ----LQTLHLQGNKISILPDDVFANLTALEKLDLSKNNIQ-KLGLRVFGERIL------------ 363
                |.||.|.||.:|.....:.:  |.|..||||.|::. :|.|...|..:|
plant   318 DSLLLTTLDLSGNNLSGPVSSIMS--TTLHTLDLSSNSLTGELPLLTGGCVLLDLSNNQFEGNLT 380

  Fly   364 -----RKLIYLDLSNNYIADLHPLALSSMPFIKELRLRRNRLV-SLDLRMFAPLRQLQLLTINEN 422
                 ..:.|||||.|:.....|.|...:.....|.|..|:|. ||..|:.....:|::|.|:.|
plant   381 RWSKWENIEYLDLSQNHFTGSFPDATPQLLRANHLNLSYNKLTGSLPERIPTHYPKLRVLDISSN 445

  Fly   423 RLE-EIDGEILDTLDRLNHLELNNNRLTF----LPDLKSSQNLLQLRNITLEGN 471
            .|| .|.|.:| ::..|..:.|.||.:|.    ||...|...||.|.:...:|:
plant   446 SLEGPIPGALL-SMPTLEEIHLQNNGMTGNIGPLPSSGSRIRLLDLSHNRFDGD 498

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32055	NP_729599.1	leucine-rich repeat	76..99	CDD:275380
		leucine-rich repeat	100..123	CDD:275380
		LRR_8	128..180	CDD:290566	17/50 (34%)
		leucine-rich repeat	128..147	CDD:275380	5/17 (29%)
		leucine-rich repeat	148..171	CDD:275380	6/22 (27%)
		leucine-rich repeat	172..192	CDD:275380	7/22 (32%)
		LRR_RI	<187..400	CDD:238064	71/304 (23%)
		LRR_8	192..251	CDD:290566	24/107 (22%)
		leucine-rich repeat	193..216	CDD:275380	10/70 (14%)
		leucine-rich repeat	217..240	CDD:275380	11/23 (48%)
		leucine-rich repeat	241..267	CDD:275380	6/25 (24%)
		leucine-rich repeat	268..291	CDD:275380	5/22 (23%)
		LRR_8	290..350	CDD:290566	22/84 (26%)
		leucine-rich repeat	292..315	CDD:275380	7/29 (24%)
		leucine-rich repeat	316..339	CDD:275380	7/22 (32%)
		LRR_8	340..400	CDD:290566	21/77 (27%)
		leucine-rich repeat	340..365	CDD:275380	10/42 (24%)
		leucine-rich repeat	366..389	CDD:275380	8/22 (36%)
		leucine-rich repeat	390..413	CDD:275380	7/23 (30%)
		LRR_8	391..448	CDD:290566	20/58 (34%)
		leucine-rich repeat	414..437	CDD:275380	9/23 (39%)
GHR1	NP_001320016.1	PLN00113	2..1036	CDD:215061	114/444 (26%)
		leucine-rich repeat	80..103	CDD:275380	6/22 (27%)
		leucine-rich repeat	104..127	CDD:275380	7/22 (32%)
		leucine-rich repeat	128..151	CDD:275380	7/22 (32%)
		leucine-rich repeat	152..175	CDD:275380	1/22 (5%)
		leucine-rich repeat	176..199	CDD:275380	1/22 (5%)
		leucine-rich repeat	200..223	CDD:275380	11/23 (48%)
		leucine-rich repeat	224..248	CDD:275380	6/25 (24%)
		leucine-rich repeat	249..272	CDD:275380	5/22 (23%)
		leucine-rich repeat	296..314	CDD:275380	3/17 (18%)
		leucine-rich repeat	344..387	CDD:275380	10/42 (24%)
		leucine-rich repeat	388..412	CDD:275380	8/23 (35%)
		leucine-rich repeat	413..436	CDD:275380	7/22 (32%)
		leucine-rich repeat	437..460	CDD:275380	9/23 (39%)
		leucine-rich repeat	461..484	CDD:275380	7/22 (32%)
		leucine-rich repeat	485..508	CDD:275380	4/14 (29%)
		leucine-rich repeat	509..532	CDD:275380
		leucine-rich repeat	533..553	CDD:275380
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000