DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG32055 and RLP40

DIOPT Version :9

Sequence 1:	NP_729599.1	Gene:	CG32055 / 39188	FlyBaseID:	FBgn0052055	Length:	534	Species:	Drosophila melanogaster
Sequence 2:	NP_566757.2	Gene:	RLP40 / 822091	AraportID:	AT3G24982	Length:	915	Species:	Arabidopsis thaliana

Alignment Length:	601	Identity:	155/601 - (25%)
Similarity:	225/601 - (37%)	Gaps:	160/601 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 ALQVLALLLLSGV-------FGKDLQECEDLGNGSYLCREIESFEQLNRYVGKNWKSVKVVNEHT 60
            :|..|.|||||.|       |...:     :|.|:....:|::|.|.     ||....:..|...
plant    38 SLNFLLLLLLSCVSPSSFFTFNNPV-----VGLGACGPHQIQAFTQF-----KNEFDTRACNHSD 92

  Fly    61 GIERAEDGELPGLSTLLQLDLSESGGVTL-GEKGLQDFKALQKLNLTHAQLDELKSEQFPNPSEM 124
            ........:..|..|:|||....||  || ....|..|..|:.|.|.|        ..|.:.|..
plant    93 PWNGVWCDDSTGAVTMLQLRACLSG--TLKPNSSLFQFHHLRSLLLPH--------NNFTSSSIS 147

  Fly   125 INFDVSYN-DILAITTKLMSGFGNLVYANFS--ENLIAVIEPN-------AF-RHMKNLRFLDLT 178
            ..|.:..| ::|::::   |||...|..:||  ..|.|::..|       :| |:::.||.||::
plant   148 SKFGMLNNLEVLSLSS---SGFLAQVPFSFSNLSMLSALVLSNNDLTGSLSFARNLRKLRVLDVS 209

  Fly   179 TNYQENITLGENANLRFLSISNNNLRDFQWCHLRVLPKLEELHLHSNWLEHLDMGIFYALPNLRV 243
            .|:             |..|.|.|            ..|.||| |..:|            |||.
plant   210 YNH-------------FSGILNPN------------SSLFELH-HIIYL------------NLRY 236

  Fly   244 LNVSNNNL-FEIKRTLFMAPGEIAPLELLDYSSNIVKVLDDSVFCRLKKLRTLNLWLNQINRIHP 307
            .|.::::| :|.        |.:..||:||.|||............|.:|..|.|.||......|
plant   237 NNFTSSSLPYEF--------GNLNKLEVLDVSSNSFFGQVPPTISNLTQLTELYLPLNHFTGSLP 293

  Fly   308 RAFLGLSSLQTLHLQGNKIS-ILPDDVFANLTALEKLDLSKNNIQKLGLRVFGERILRKLIYLDL 371
             ....|:.|..|||.||..| .:|..:| .:..|..|.|..||:.. .:.|.......:|..|.|
plant   294 -LVQNLTKLSILHLFGNHFSGTIPSSLF-TMPFLSYLSLKGNNLNG-SIEVPNSSSSSRLESLHL 355

  Fly   372 SNNYIAD--LHPLALSSMPFIKELRLR-RNRLVSLDLRMFAPLRQLQLL---------------- 417
            ..|:...  |.|  :|.:..:|||.|. .|....:||.:|:.|:.|.||
plant   356 GENHFEGKILEP--ISKLINLKELDLSFLNTSYPIDLSLFSSLKSLLLLDLSGDWISKASLTLDS 418

  Fly   418 ----TINENRLEEID----GEILDTLDRLNHLELNNNRLT--------FLPDLKS---SQNLL-- 461
                |:...|||..|    ..:..||..|.::.|:|||::        .||.|.|   :.|||
plant   419 YIPSTLEVLRLEHCDISDFPNVFKTLHNLEYIALSNNRISGKFPEWLWSLPRLSSVFITDNLLTG 483

  Fly   462 -QLRNITLEGNPWQCLCLDEITSWLNGR------HVSYARPSSAYFSGRKPLCVVT--------- 510
             :..:..|..:..|.|.||  |:.|.|.      .::|.......|.|..||.:..
plant   484 FEGSSEVLVNSSVQILSLD--TNSLEGALPHLPLSINYFSAIDNRFGGDIPLSICNRSSLDVLDL 546

  Fly   511 -------PMDKCLRDL 519
                   |:..||.:|
plant   547 SYNNFTGPIPPCLSNL 562

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32055	NP_729599.1	leucine-rich repeat	76..99	CDD:275380	9/23 (39%)
		leucine-rich repeat	100..123	CDD:275380	5/22 (23%)
		LRR_8	128..180	CDD:290566	17/62 (27%)
		leucine-rich repeat	128..147	CDD:275380	5/19 (26%)
		leucine-rich repeat	148..171	CDD:275380	8/32 (25%)
		leucine-rich repeat	172..192	CDD:275380	5/19 (26%)
		LRR_RI	<187..400	CDD:238064	59/217 (27%)
		LRR_8	192..251	CDD:290566	14/58 (24%)
		leucine-rich repeat	193..216	CDD:275380	4/22 (18%)
		leucine-rich repeat	217..240	CDD:275380	6/22 (27%)
		leucine-rich repeat	241..267	CDD:275380	6/26 (23%)
		leucine-rich repeat	268..291	CDD:275380	8/22 (36%)
		LRR_8	290..350	CDD:290566	20/60 (33%)
		leucine-rich repeat	292..315	CDD:275380	7/22 (32%)
		leucine-rich repeat	316..339	CDD:275380	9/23 (39%)
		LRR_8	340..400	CDD:290566	18/62 (29%)
		leucine-rich repeat	340..365	CDD:275380	6/24 (25%)
		leucine-rich repeat	366..389	CDD:275380	7/24 (29%)
		leucine-rich repeat	390..413	CDD:275380	9/23 (39%)
		LRR_8	391..448	CDD:290566	23/81 (28%)
		leucine-rich repeat	414..437	CDD:275380	10/46 (22%)
RLP40	NP_566757.2	LRR_RI	97..>263	CDD:238064	59/224 (26%)
		LRR_8	130..190	CDD:290566	18/70 (26%)
		leucine-rich repeat	131..155	CDD:275380	7/31 (23%)
		leucine-rich repeat	156..179	CDD:275380	7/25 (28%)
		leucine-rich repeat	180..202	CDD:275380	5/21 (24%)
		LRR_8	201..264	CDD:290566	29/108 (27%)
		leucine-rich repeat	203..228	CDD:275380	13/50 (26%)
		leucine-rich repeat	229..253	CDD:275380	8/43 (19%)
		leucine-rich repeat	254..277	CDD:275380	8/22 (36%)
		leucine-rich repeat	278..300	CDD:275380	7/22 (32%)
		leucine-rich repeat	301..324	CDD:275380	9/23 (39%)
		leucine-rich repeat	325..349	CDD:275380	6/24 (25%)
		leucine-rich repeat	350..371	CDD:275380	7/22 (32%)
		LRR_8	422..481	CDD:290566	17/58 (29%)
		leucine-rich repeat	424..446	CDD:275380	6/21 (29%)
		leucine-rich repeat	447..468	CDD:275380	5/20 (25%)
		leucine-rich repeat	471..495	CDD:275380	6/23 (26%)
		leucine-rich repeat	517..540	CDD:275380	5/22 (23%)
		leucine-rich repeat	541..585	CDD:275380	4/22 (18%)
		LRR_8	560..620	CDD:290566	1/3 (33%)
		leucine-rich repeat	563..583	CDD:275380	155/601 (26%)
		leucine-rich repeat	586..609	CDD:275380
		leucine-rich repeat	610..633	CDD:275380
		leucine-rich repeat	634..660	CDD:275380
		leucine-rich repeat	735..758	CDD:275380
		leucine-rich repeat	759..782	CDD:275380
		LRR_8	762..817	CDD:290566
		leucine-rich repeat	783..806	CDD:275380
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000