DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32055 and Lrrc15

DIOPT Version :9

Sequence 1:	NP_729599.1	Gene:	CG32055 / 39188	FlyBaseID:	FBgn0052055	Length:	534	Species:	Drosophila melanogaster
Sequence 2:	NP_083249.1	Gene:	Lrrc15 / 74488	MGIID:	1921738	Length:	579	Species:	Mus musculus

Alignment Length:	402	Identity:	121/402 - (30%)
Similarity:	181/402 - (45%)	Gaps:	56/402 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    99 ALQKLNLTHAQLDELKSEQFPNPSEMINFDVSYNDILAITTKLMSGFGNLVYANFSENLIAVIEP 163
            :||.|| ||  :.||..::|.|.|.:|...:..|:                        :|.|.|
Mouse    57 SLQILN-TH--ITELPEDKFLNISALIALKMEKNE------------------------LANIMP 94

  Fly   164 NAFRHMKNLRFLDLTTNYQENITL---GENANLRFLSISNNNLRDFQWCHLRVLPKLEELHLHSN 225
            .|||::.:||.|.|..|..:|:.:   .:..||..|.:|||.|...|.........|:||.|:.|
Mouse    95 GAFRNLGSLRHLSLANNKLKNLPVRLFQDVNNLETLLLSNNQLVQIQPAQFSQFSNLKELQLYGN 159

  Fly   226 WLEHLDMGIFYALPNLRVLNVSNNNLFEIKRTLFMAPGEIAPLELLDYSSNIVKVLDDSVFCRLK 290
            .||::..|:|..|..|..||:.||....:...:|...|.:..|.|.:   |.:..:....|..|.
Mouse   160 NLEYIPEGVFDHLVGLTKLNLGNNGFTHLSPRVFQHLGNLQVLRLYE---NRLSDIPMGTFDALG 221

  Fly   291 KLRTLNLWLNQINRIHPRAFLGLSSLQTLHLQGNKISILPDDVFANLTALEKLDLSKNNIQKLGL 355
            .|:.|.|..|||..:.|..|....:||.|:|..|.||.||..:|..|..|.||.|..|::::|..
Mouse   222 NLQELALQENQIGTLSPGLFHNNRNLQRLYLSNNHISHLPPGIFMQLPHLNKLTLFGNSLKELSP 286

  Fly   356 RVFGE----------------------RILRKLIYLDLSNNYIADLHPLALSSMPFIKELRLRRN 398
            .|||.                      ..|.:|..|.||:|.::.:.|.|.:.:..::||.|..|
Mouse   287 GVFGPMPNLRELWLYNNHITSLPDNAFSHLNQLQVLILSHNQLSYISPGAFNGLTNLRELSLHTN 351

  Fly   399 RLVSLDLRMFAPLRQLQLLTINENRLEEIDGEILDTLDRLNHLELNNNRLTFLPDLKSSQNLLQL 463
            .|..||..:|..|..|:.:::..|||.::.|.|...::.|..::|.||.|..|| |....:|..|
Mouse   352 ALQDLDGNVFRSLANLRNVSLQNNRLRQLPGSIFANVNGLMTIQLQNNNLENLP-LGIFDHLGNL 415

  Fly   464 RNITLEGNPWQC 475
            ..:.|..|||:|
Mouse   416 CELRLYDNPWRC 427

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32055	NP_729599.1	leucine-rich repeat	76..99	CDD:275380	121/402 (30%)
		leucine-rich repeat	100..123	CDD:275380	10/22 (45%)
		LRR_8	128..180	CDD:290566	11/51 (22%)
		leucine-rich repeat	128..147	CDD:275380	1/18 (6%)
		leucine-rich repeat	148..171	CDD:275380	6/22 (27%)
		leucine-rich repeat	172..192	CDD:275380	6/22 (27%)
		LRR_RI	<187..400	CDD:238064	70/237 (30%)
		LRR_8	192..251	CDD:290566	23/58 (40%)
		leucine-rich repeat	193..216	CDD:275380	7/22 (32%)
		leucine-rich repeat	217..240	CDD:275380	10/22 (45%)
		leucine-rich repeat	241..267	CDD:275380	7/25 (28%)
		leucine-rich repeat	268..291	CDD:275380	5/22 (23%)
		LRR_8	290..350	CDD:290566	24/59 (41%)
		leucine-rich repeat	292..315	CDD:275380	8/22 (36%)
		leucine-rich repeat	316..339	CDD:275380	11/22 (50%)
		LRR_8	340..400	CDD:290566	21/81 (26%)
		leucine-rich repeat	340..365	CDD:275380	10/46 (22%)
		leucine-rich repeat	366..389	CDD:275380	7/22 (32%)
		leucine-rich repeat	390..413	CDD:275380	9/22 (41%)
		LRR_8	391..448	CDD:290566	19/56 (34%)
		leucine-rich repeat	414..437	CDD:275380	6/22 (27%)
Lrrc15	NP_083249.1	LRR 1	54..75		9/20 (45%)
		leucine-rich repeat	58..78	CDD:275380	10/22 (45%)
		LRR 2	78..99		7/44 (16%)
		PLN00113	82..>401	CDD:215061	98/345 (28%)
		LRR 3	102..123		6/20 (30%)
		leucine-rich repeat	103..126	CDD:275380	6/22 (27%)
		LRR 4	126..147		8/20 (40%)
		leucine-rich repeat	127..150	CDD:275380	7/22 (32%)
		LRR 5	150..171		9/20 (45%)
		leucine-rich repeat	151..174	CDD:275380	10/22 (45%)
		LRR 6	174..195		6/20 (30%)
		leucine-rich repeat	175..198	CDD:275380	6/22 (27%)
		LRR 7	198..219		4/23 (17%)
		leucine-rich repeat	199..222	CDD:275380	5/25 (20%)
		LRR 8	222..243		8/20 (40%)
		leucine-rich repeat	223..246	CDD:275380	8/22 (36%)
		LRR 9	246..267		10/20 (50%)
		leucine-rich repeat	247..270	CDD:275380	11/22 (50%)
		LRR 10	270..291		8/20 (40%)
		leucine-rich repeat	271..294	CDD:275380	9/22 (41%)
		LRR 11	294..315		0/20 (0%)
		leucine-rich repeat	295..318	CDD:275380	1/22 (5%)
		LRR 12	318..339		7/20 (35%)
		leucine-rich repeat	319..342	CDD:275380	7/22 (32%)
		LRR 13	342..363		8/20 (40%)
		leucine-rich repeat	343..364	CDD:275380	8/20 (40%)
		LRR 14	366..387		6/20 (30%)
		leucine-rich repeat	367..387	CDD:275380	6/19 (32%)
		LRR 15	390..411		8/21 (38%)
		leucine-rich repeat	391..412	CDD:275380	8/21 (38%)
		LRRCT	423..>462	CDD:214507	4/5 (80%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	476..509
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910