Protein Alignment CG32055 and ASPN

DIOPT Version :10

• Sequence 1: NP_729599.1
• Gene: CG32055 / 39188
• FlyBaseID: FBgn0052055
• Length: 534
• Species: Drosophila melanogaster
• Sequence 2: NP_060150.4
• Gene: ASPN / 54829
• HGNCID: 14872
• Length: 379
• Species: Homo sapiens
• Alignment Length: 267
• Identity: 72/267 - (26%)
• Similarity: 117/267 - (43%)
• Gaps: 49/267 - (18%)

  Fly   209 CHLRVLPKLEELHLHSNWLEHLDMGIFYALPNL----RVLNVSNNNLFEIKRTLFMAPGEIAPLE 269
            |:.||        :|.:     |:|:.....|:    |:|::.||.:.|||...|..   :..|.
Human    80 CYSRV--------VHCS-----DLGLTSVPTNIPFDTRMLDLQNNKIKEIKENDFKG---LTSLY 128

  Fly   270 LLDYSSNIVKVLDDSVFCRLKKLRTLNLWLNQINRIHPRAFLGL-SSLQTLHLQGNKISILPDDV 333
            .|..::|.:..:....|...||||.|.|..||::.|.    |.| .||..|.:..||:..:..|.
Human   129 GLILNNNKLTKIHPKAFLTTKKLRRLYLSHNQLSEIP----LNLPKSLAELRIHENKVKKIQKDT 189

  Fly   334 FANLTALEKLDLSKNNIQKLGLR--------VFGERILRKLIYLDLSNNYIADLHPLALSSMPFI 390
            |..:.||..|::|.|.:...|:.        ||..||..            |.|..:.....|.:
Human   190 FKGMNALHVLEMSANPLDNNGIEPGAFEGVTVFHIRIAE------------AKLTSVPKGLPPTL 242

  Fly   391 KELRLRRNRLVSLDLRMFAPLRQLQLLTINENRLEEIDGEILDTLDRLNHLELNNNRL----TFL 451
            .||.|..|::.:::|..|...::||.|.:..|::.:|:...|..:.|:..:.|.||:|    :.|
Human   243 LELHLDYNKISTVELEDFKRYKELQRLGLGNNKITDIENGSLANIPRVREIHLENNKLKKIPSGL 307

  Fly   452 PDLKSSQ 458
            |:||..|
Human   308 PELKYLQ 314

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32055	NP_729599.1	leucine-rich repeat	76..99	CDD:275380
		leucine-rich repeat	100..123	CDD:275380
		LRR_8	126..180	CDD:404697
		leucine-rich repeat	128..147	CDD:275380
		leucine-rich repeat	148..171	CDD:275380
		LRR	171..>486	CDD:443914	72/267 (27%)
		leucine-rich repeat	172..192	CDD:275380
		leucine-rich repeat	193..216	CDD:275380	3/6 (50%)
		leucine-rich repeat	217..240	CDD:275380	3/22 (14%)
		leucine-rich repeat	241..267	CDD:275380	8/29 (28%)
		leucine-rich repeat	268..291	CDD:275380	4/22 (18%)
		leucine-rich repeat	292..315	CDD:275380	9/23 (39%)
		leucine-rich repeat	316..339	CDD:275380	6/22 (27%)
		leucine-rich repeat	340..365	CDD:275380	9/32 (28%)
		leucine-rich repeat	366..389	CDD:275380	2/22 (9%)
		leucine-rich repeat	390..413	CDD:275380	6/22 (27%)
		leucine-rich repeat	414..437	CDD:275380	6/22 (27%)
ASPN	NP_060150.4	LRRNT	73..103	CDD:214470	7/35 (20%)
		leucine-rich repeat	83..102	CDD:275380	6/31 (19%)
		leucine-rich repeat	103..126	CDD:275380	8/25 (32%)
		LRR	106..>323	CDD:443914	64/228 (28%)
		leucine-rich repeat	127..150	CDD:275380	4/22 (18%)
		leucine-rich repeat	151..171	CDD:275380	9/23 (39%)
		leucine-rich repeat	172..195	CDD:275380	6/22 (27%)
		leucine-rich repeat	196..221	CDD:275380	5/24 (21%)
		leucine-rich repeat	242..265	CDD:275380	6/22 (27%)
		leucine-rich repeat	266..289	CDD:275380	6/22 (27%)
		leucine-rich repeat	313..332	CDD:275380	1/2 (50%)