DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG32055 and Lrrc32

DIOPT Version :9

Sequence 1:NP_729599.1 Gene:CG32055 / 39188 FlyBaseID:FBgn0052055 Length:534 Species:Drosophila melanogaster
Sequence 2:NP_001106850.1 Gene:Lrrc32 / 434215 MGIID:93882 Length:663 Species:Mus musculus


Alignment Length:497 Identity:128/497 - (25%)
Similarity:195/497 - (39%) Gaps:140/497 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly    38 SFEQLNRYVGKNWKSVKVVNEHTGI-ERAEDGELPGLSTLLQLDLSESGGVTLGEKGLQDFKALQ 101
            |..:|.|:......:|:.::.|:.: ...|||....|..|..|:||.:....:.:..||.   ||
Mouse   161 SLTRLARHTFWGMPAVEQLDLHSNVLMDIEDGAFEALPHLTHLNLSRNSLTCISDFSLQQ---LQ 222

  Fly   102 KLNLTHAQLDELKSEQFPNPSEMINFDVSYNDILAITTKL-----MSGFGNLVYANFSENLIAV- 160
            .|:|:...::..::.    |.....|.:::.|:.  ..||     ::.|..|:|.|.|.|||.: 
Mouse   223 VLDLSCNSIEAFQTA----PEPQAQFQLAWLDLR--ENKLLHFPDLAVFPRLIYLNVSNNLIQLP 281

  Fly   161 ------------------IEP------NAFRH-MKNLRFLDLTTN--------YQENITLGENAN 192
                              ..|      ||..| :..|..|||:.|        :.|::|     :
Mouse   282 AGLPRGSEDLHAPSEGWSASPLSNPSRNASTHPLSQLLNLDLSYNEIELVPASFLEHLT-----S 341

  Fly   193 LRFLSISNNNLRDFQWCHLRVLPKLEELHLHSNWLEHLDMGIFYALPNLRVLNVSNNNLFEIKRT 257
            ||||::|.|.||.|:...:..||.|..|.|..|.||.|::|                        
Mouse   342 LRFLNLSRNCLRSFEARQVDSLPCLVLLDLSHNVLEALELG------------------------ 382

  Fly   258 LFMAPGEIAPLELLDYSSNIVKVLDDSVFCRLKKLRTLNLWLNQINRIHPRAFLGLSSLQTLHLQ 322
                                .|||.        .|:||.|..|.:..:.|..|..|:|||.|:||
Mouse   383 --------------------TKVLG--------SLQTLLLQDNALQELPPYTFASLASLQRLNLQ 419

  Fly   323 GNKISIL--------PDDV-FANLTALEKLDLSKNNIQKLGLRVFGERILRKLIYLDLSNNYIAD 378
            ||::|..        |..| |:.:..|..|:::.|:   :|:...|..:...|..||||.|...|
Mouse   420 GNQVSPCGGPAEPGPPGCVDFSGIPTLHVLNMAGNS---MGMLRAGSFLHTPLTELDLSTNPGLD 481

  Fly   379 LHPLALSSM-PFIKELRLRRNRLVSL--DLRMFAPLRQLQLLTINENRLEEIDG-------EILD 433
            :...||..: ..::.|.|:.|.|..|  ||..|..|::|.|.   ||:|..:..       |:||
Mouse   482 VATGALVGLEASLEVLELQGNGLTVLRVDLPCFLRLKRLNLA---ENQLSHLPAWTRAVSLEVLD 543

  Fly   434 TLDRLNHLELNNNRLTFLPDLKSSQNLLQLRNITLEGNPWQC 475
                     |.||..:.||..........||.:.|:|||..|
Mouse   544 ---------LRNNSFSLLPGNAMGGLETSLRRLYLQGNPLSC 576

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG32055NP_729599.1 leucine-rich repeat 76..99 CDD:275380 6/22 (27%)
leucine-rich repeat 100..123 CDD:275380 5/22 (23%)
LRR_8 128..180 CDD:290566 19/82 (23%)
leucine-rich repeat 128..147 CDD:275380 4/23 (17%)
leucine-rich repeat 148..171 CDD:275380 11/48 (23%)
leucine-rich repeat 172..192 CDD:275380 7/27 (26%)
LRR_RI <187..400 CDD:238064 59/222 (27%)
LRR_8 192..251 CDD:290566 19/58 (33%)
leucine-rich repeat 193..216 CDD:275380 10/22 (45%)
leucine-rich repeat 217..240 CDD:275380 8/22 (36%)
leucine-rich repeat 241..267 CDD:275380 0/25 (0%)
leucine-rich repeat 268..291 CDD:275380 3/22 (14%)
LRR_8 290..350 CDD:290566 23/68 (34%)
leucine-rich repeat 292..315 CDD:275380 8/22 (36%)
leucine-rich repeat 316..339 CDD:275380 11/31 (35%)
LRR_8 340..400 CDD:290566 17/60 (28%)
leucine-rich repeat 340..365 CDD:275380 5/24 (21%)
leucine-rich repeat 366..389 CDD:275380 9/23 (39%)
leucine-rich repeat 390..413 CDD:275380 9/24 (38%)
LRR_8 391..448 CDD:290566 20/65 (31%)
leucine-rich repeat 414..437 CDD:275380 8/29 (28%)
Lrrc32NP_001106850.1 LRR_RI 37..278 CDD:393385 30/125 (24%)
LRR 1. /evidence=ECO:0000255 49..72
leucine-rich repeat 55..75 CDD:275380
LRR 2. /evidence=ECO:0000255 73..96
leucine-rich repeat 76..99 CDD:275380
LRR 3. /evidence=ECO:0000255 98..123
leucine-rich repeat 100..126 CDD:275380
PLN00113 123..>562 CDD:215061 121/481 (25%)
LRR 4. /evidence=ECO:0000255 125..148
leucine-rich repeat 127..151 CDD:275380
LRR 5. /evidence=ECO:0000255 149..172 3/10 (30%)
leucine-rich repeat 152..175 CDD:275380 3/13 (23%)
LRR 6. /evidence=ECO:0000255 174..196 5/21 (24%)
leucine-rich repeat 176..199 CDD:275380 6/22 (27%)
LRR 7. /evidence=ECO:0000255 197..220 6/22 (27%)
leucine-rich repeat 200..220 CDD:275380 5/19 (26%)
leucine-rich repeat 221..245 CDD:275380 5/27 (19%)
LRR 8. /evidence=ECO:0000255 222..241 4/22 (18%)
LRR 9. /evidence=ECO:0000255 243..267 5/25 (20%)
leucine-rich repeat 246..267 CDD:275380 4/22 (18%)
LRR 10. /evidence=ECO:0000255 269..287 6/17 (35%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 291..311 2/19 (11%)
LRR 11. /evidence=ECO:0000255 315..338 5/22 (23%)
leucine-rich repeat 318..341 CDD:275380 7/27 (26%)
LRR 12. /evidence=ECO:0000255 340..362 10/26 (38%)
leucine-rich repeat 342..365 CDD:275380 10/22 (45%)
LRR 13. /evidence=ECO:0000255 363..386 11/66 (17%)
leucine-rich repeat 366..388 CDD:275380 11/73 (15%)
LRR 14. /evidence=ECO:0000255 387..409 7/29 (24%)
leucine-rich repeat 389..412 CDD:275380 8/22 (36%)
LRR 15. /evidence=ECO:0000255 411..433 9/21 (43%)
leucine-rich repeat 413..445 CDD:275380 11/31 (35%)
LRR 16. /evidence=ECO:0000255 443..466 5/25 (20%)
leucine-rich repeat 446..467 CDD:275380 5/23 (22%)
LRR 17. /evidence=ECO:0000255 468..489 9/20 (45%)
leucine-rich repeat 469..493 CDD:275380 9/23 (39%)
LRR 18. /evidence=ECO:0000255 491..514 7/22 (32%)
leucine-rich repeat 494..516 CDD:275380 8/21 (38%)
LRR 19. /evidence=ECO:0000255 515..539 6/26 (23%)
leucine-rich repeat 517..538 CDD:275380 6/23 (26%)
leucine-rich repeat 539..560 CDD:275380 8/29 (28%)
LRR 20. /evidence=ECO:0000255 541..559 7/26 (27%)
LRR 21. /evidence=ECO:0000255 561..584 7/16 (44%)
leucine-rich repeat 564..576 CDD:275378 6/11 (55%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
11.000

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