DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32055 and CG18249

DIOPT Version :9

Sequence 1:	NP_729599.1	Gene:	CG32055 / 39188	FlyBaseID:	FBgn0052055	Length:	534	Species:	Drosophila melanogaster
Sequence 2:	NP_001163549.1	Gene:	CG18249 / 40964	FlyBaseID:	FBgn0037553	Length:	559	Species:	Drosophila melanogaster

Alignment Length:	471	Identity:	116/471 - (24%)
Similarity:	183/471 - (38%)	Gaps:	126/471 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   130 SYNDILAITTKLMSGFGNLVYANFSENLIAVIEPNAFRHMKNLRFLDLTTNYQENITLGENANLR 194
            |...|..:..:|..|...||..|.:...|:   ..:.|.::||..|.:     :..:||.
  Fly    66 SRQSITWLVLQLTPGLRTLVIRNCATYHIS---KESLRPVENLTSLQM-----QGTSLGV----- 117

  Fly   195 FLSISNNNLRDFQWCHLRVLPKLEELHLHSNWLEHLDMGIFYALPNLRVLNVSNNNLFEIKRTLF 259
                    |||..:   ..:|:||.|.|..|::..:.:..|..|..||:|.:..|.:.||   |.
  Fly   118 --------LRDQIF---NAVPRLEILQLSQNFIHTVHVAAFQGLSKLRLLGLQGNAIAEI---LS 168

  Fly   260 MAPGEIAPLELLDYSSNIVKVLDDSVFCRLKKLRTLNLWLNQINRIHPRAF-------------- 310
            .....:..|..||.|.|.:..|..::|.:.|||:||.|..|.:..:.|...
  Fly   169 STLDPLMELVHLDLSRNELTTLPQNIFAKNKKLQTLLLNGNPLRILMPDVLGSLPNLRLLDLGHA 233

  Fly   311 -------LGLSSLQTL---------------------------HLQ-GNKISILPDDVFANL--- 337
                   |.|:::|.|                           ||| |||.|::..|:..||
  Fly   234 AELEVMTLNLTNVQNLVLEGSSLSSLVINGGFIKLQAGNNELNHLQVGNKSSVIEMDLHGNLLNG 298

  Fly   338 --TA--------LEKLDLSKNNIQKL-----GLRVFGER---ILRKLIYLDLSNNYIADLHPLA- 383
              ||        |::||||||.|:.|     ||...|.:   ||..|.:|:|:||.:..|.|.:
  Fly   299 NDTAALLRGMWNLQRLDLSKNRIEALPQHGSGLDASGTQELLILPSLKFLNLANNQLVRLPPESP 363

  Fly   384 -LSSMPFIKELRLRRNRLVSLDLRMFAPLRQLQLLTINENRLEEIDGEILDTLDRLNHLELNNNR 447
             |||.  :..|.|..|.:::||:.:...|..|:.|.:..|||..|           |:.:|:...
  Fly   364 ILSSR--LSYLDLSHNLMLTLDVAILRSLSVLKGLYVEGNRLNTI-----------NYQKLHEEH 415

  Fly   448 LTFLPDLKSSQNLLQLRNITLEGNPWQCLCLDEITSWLNGRHVS-YARPSSAYFSGRKPLCVVTP 511
                |||.         .:.|..|||......::..:...|.|. .|||.:...:....:.:..|
  Fly   416 ----PDLS---------ELGLHDNPWSSGLYRKMFLYFTDRGVHLQARPQNRVLNKSSRVDIDWP 467

  Fly   512 MDKCLRDLQETKAQGI 527
            .::...:.|:....|:
  Fly   468 PNEGQAEAQKMDPPGV 483

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32055	NP_729599.1	leucine-rich repeat	76..99	CDD:275380
		leucine-rich repeat	100..123	CDD:275380
		LRR_8	128..180	CDD:290566	12/49 (24%)
		leucine-rich repeat	128..147	CDD:275380	4/16 (25%)
		leucine-rich repeat	148..171	CDD:275380	5/22 (23%)
		leucine-rich repeat	172..192	CDD:275380	4/19 (21%)
		LRR_RI	<187..400	CDD:238064	78/284 (27%)
		LRR_8	192..251	CDD:290566	15/58 (26%)
		leucine-rich repeat	193..216	CDD:275380	3/22 (14%)
		leucine-rich repeat	217..240	CDD:275380	7/22 (32%)
		leucine-rich repeat	241..267	CDD:275380	7/25 (28%)
		leucine-rich repeat	268..291	CDD:275380	7/22 (32%)
		LRR_8	290..350	CDD:290566	31/121 (26%)
		leucine-rich repeat	292..315	CDD:275380	8/43 (19%)
		leucine-rich repeat	316..339	CDD:275380	12/55 (22%)
		LRR_8	340..400	CDD:290566	27/69 (39%)
		leucine-rich repeat	340..365	CDD:275380	14/32 (44%)
		leucine-rich repeat	366..389	CDD:275380	10/24 (42%)
		leucine-rich repeat	390..413	CDD:275380	6/22 (27%)
		LRR_8	391..448	CDD:290566	14/56 (25%)
		leucine-rich repeat	414..437	CDD:275380	6/22 (27%)
CG18249	NP_001163549.1	leucine-rich repeat	57..80	CDD:275380	3/13 (23%)
		LRR_8	104..163	CDD:290566	20/79 (25%)
		leucine-rich repeat	105..128	CDD:275380	7/43 (16%)
		LRR_RI	107..438	CDD:238064	97/380 (26%)
		leucine-rich repeat	129..152	CDD:275380	7/22 (32%)
		leucine-rich repeat	153..176	CDD:275380	7/25 (28%)
		LRR_8	176..232	CDD:290566	15/55 (27%)
		leucine-rich repeat	177..200	CDD:275380	7/22 (32%)
		leucine-rich repeat	201..224	CDD:275380	6/22 (27%)
		leucine-rich repeat	225..258	CDD:275380	4/32 (13%)
		leucine-rich repeat	259..310	CDD:275380	12/50 (24%)
		leucine-rich repeat	311..344	CDD:275380	14/32 (44%)
		LRR_8	343..403	CDD:290566	19/61 (31%)
		leucine-rich repeat	345..368	CDD:275380	9/22 (41%)
		leucine-rich repeat	369..390	CDD:275380	5/20 (25%)
		leucine-rich repeat	393..417	CDD:275380	8/38 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45453608
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840