DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32055 and rtn4rl2b

DIOPT Version :9

Sequence 1:	NP_729599.1	Gene:	CG32055 / 39188	FlyBaseID:	FBgn0052055	Length:	534	Species:	Drosophila melanogaster
Sequence 2:	NP_982350.1	Gene:	rtn4rl2b / 403309	ZFINID:	ZDB-GENE-040310-2	Length:	457	Species:	Danio rerio

Alignment Length:	277	Identity:	73/277 - (26%)
Similarity:	117/277 - (42%)	Gaps:	47/277 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   229 HLDMGI------FYALP------NLRVLNVSNNNLFEIKRTLFMAPGEIAPLELLDYSSNIVKVL 281
            |:.|.:      |.::|      :.||. :.||.:.|::...|....::..|    ||:||..:
Zfish    49 HMPMTVSCQSQNFTSVPAGVPYDSQRVF-LQNNRITELRADSFGFETQVLWL----YSNNITWI- 107

  Fly   282 DDSVFCRLKKLRTLNLWLN-QINRIHPRAFLGLSSLQTLHLQGNKISILPDDVFANLTALEKLDL 345
            :...|..|:.|..|:|..| .:.|:...||.||..||:||:....::.||.|:|..|.:|:.|.|
Zfish   108 EAGAFSNLRVLEELDLSDNPSLRRLDGGAFRGLERLQSLHMHRCHLTELPADLFHKLYSLQFLYL 172

  Fly   346 SKNNIQKLGLRVFGERILRKLIYLDLSNNYIADLHPLALSSMPFIKELRLRRNRLVSLDLRMFAP 410
            .:|.:..|...:|.:  |..|.:|.|..|.|..:...|...:..:..|.|..||:..:..|.|..
Zfish   173 QENQLTNLPDGLFSD--LVNLTHLFLHGNRIRTVSENAFRGLVNLDRLLLHDNRIRQVHRRSFRD 235

  Fly   411 LRQLQLLTINENRLEEIDGEILDTLDRLNHLELNNNRLTFLPDLKSSQNLLQLRNITLEGNPWQC 475
            |.:|.:|.:..|.|:|:.|:.|.....:..|.||                         ||||.|
Zfish   236 LGRLTILYLFNNSLQELPGQALRDTSSVQFLRLN-------------------------GNPWTC 275

  Fly   476 LC-LDEITSWLNGRHVS 491
            .| ...:..|.....:|
Zfish   276 GCEARSLWEWFRKARIS 292

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32055	NP_729599.1	leucine-rich repeat	76..99	CDD:275380
		leucine-rich repeat	100..123	CDD:275380
		LRR_8	128..180	CDD:290566
		leucine-rich repeat	128..147	CDD:275380
		leucine-rich repeat	148..171	CDD:275380
		leucine-rich repeat	172..192	CDD:275380
		LRR_RI	<187..400	CDD:238064	51/183 (28%)
		LRR_8	192..251	CDD:290566	8/33 (24%)
		leucine-rich repeat	193..216	CDD:275380
		leucine-rich repeat	217..240	CDD:275380	4/22 (18%)
		leucine-rich repeat	241..267	CDD:275380	6/25 (24%)
		leucine-rich repeat	268..291	CDD:275380	7/22 (32%)
		LRR_8	290..350	CDD:290566	22/60 (37%)
		leucine-rich repeat	292..315	CDD:275380	9/23 (39%)
		leucine-rich repeat	316..339	CDD:275380	9/22 (41%)
		LRR_8	340..400	CDD:290566	16/59 (27%)
		leucine-rich repeat	340..365	CDD:275380	7/24 (29%)
		leucine-rich repeat	366..389	CDD:275380	6/22 (27%)
		leucine-rich repeat	390..413	CDD:275380	7/22 (32%)
		LRR_8	391..448	CDD:290566	17/56 (30%)
		leucine-rich repeat	414..437	CDD:275380	7/22 (32%)
rtn4rl2b	NP_982350.1	LRRNT	40..71	CDD:214470	4/21 (19%)
		leucine-rich repeat	53..70	CDD:275380	2/16 (13%)
		leucine-rich repeat	73..93	CDD:275380	6/20 (30%)
		LRR_RI	93..>326	CDD:238064	63/232 (27%)
		LRR_8	95..153	CDD:290566	20/62 (32%)
		leucine-rich repeat	95..117	CDD:275380	7/26 (27%)
		leucine-rich repeat	118..142	CDD:275380	9/23 (39%)
		leucine-rich repeat	143..166	CDD:275380	9/22 (41%)
		LRR_8	166..225	CDD:290566	16/60 (27%)
		LRR_4	166..206	CDD:289563	12/41 (29%)
		leucine-rich repeat	167..190	CDD:275380	7/24 (29%)
		leucine-rich repeat	191..214	CDD:275380	6/22 (27%)
		LRR_8	214..272	CDD:290566	18/82 (22%)
		leucine-rich repeat	215..238	CDD:275380	7/22 (32%)
		leucine-rich repeat	239..262	CDD:275380	7/22 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.000