DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32055 and trn

DIOPT Version :9

Sequence 1:	NP_729599.1	Gene:	CG32055 / 39188	FlyBaseID:	FBgn0052055	Length:	534	Species:	Drosophila melanogaster
Sequence 2:	NP_001261796.1	Gene:	trn / 39491	FlyBaseID:	FBgn0010452	Length:	751	Species:	Drosophila melanogaster

Alignment Length:	469	Identity:	117/469 - (24%)
Similarity:	195/469 - (41%)	Gaps:	90/469 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   109 QLDELKSEQFPNPSEMINFDVSYNDILAITTKLMSGFGNLVYANFSENLIAVIEPNAFRHMKNLR 173
            |||.|.....|:...::   :..|.|..|.:.:.. :..|.:.:.|.|.:..|....|.:.|.|:
  Fly    49 QLDVLPIALNPSIQRLV---IKSNKIKTIDSSIQF-YAELTFLDLSSNHLMTIPQRTFAYQKKLQ 109

  Fly   174 FLDLTTNYQENITLGENANLRFLSISN---NNLRDFQWCHLR-----VLPKLEELHLHSNWLEHL 230
            .:.|..|     .:|:.:|..|:.:|.   .|||..|...|.     .|.|:|||:|..|.:.:|
  Fly   110 EVHLNHN-----KIGQISNKTFIGLSAVTVLNLRGNQISELHQGTFTPLLKIEELNLGENRIGYL 169

  Fly   231 DMGIFYALPNLRVLNVSNNNLFEI-KRTLFMAPGEIAPLELLDYSSNIVKVLDDSVFCRLKKLRT 294
            |...|..|..||:|.:.:|.|..: ...:|.|...:|.|.|   ..|.::.:....|..||.|..
  Fly   170 DPKAFDGLSQLRILYLDDNALTTVPDPVIFQAMPSLAELFL---GMNTLQSIQADAFQDLKGLTR 231

  Fly   295 LNLWLNQINRIHPRAFLGLSSLQTLHLQGNKISILPDDVFANLTALEKLDLSKNNIQKLG----- 354
            |.|....:..|...:||||..|:.|.|..|::..:|....:.|..||:|.|.:|:.:.:.
  Fly   232 LELKGASLRNISHDSFLGLQELRILDLSDNRLDRIPSVGLSKLVRLEQLSLGQNDFEVISEGAFM 296

  Fly   355 -------LRVFGERILRKLI-----------YLDLSNN-YIADLHPLALSSMPFIKELRLRRNRL 400
                   |.|.|...|::::           ||:||:| .:.::...|||.:..:|.:.|:.|.|
  Fly   297 GLKQLKRLEVNGALRLKRVMTGAFSDNGNLEYLNLSSNKMLLEVQEGALSGLSQLKHVVLKANAL 361

  Fly   401 VSLDLRMFAPLRQLQLLTINENRLEEIDGEILDTLDRLNHLELNNNRLTFLPDLKSSQNLLQLRN 465
            .||...:| |.:.||.|.::||.|.                  .:.|:.:|      .|||..:|
  Fly   362 TSLAEGLF-PWKDLQTLDLSENPLS------------------CDCRVMWL------HNLLVAKN 401

  Fly   466 ITLEGNPWQCLCLDEITSWLNG---RHVSYARPSSAYFSGRKPLCV----------VTPMD---- 513
            .: :.:..:.||  |....|.|   ||::.|.....:...||...:          :|.:.
  Fly   402 AS-QDDVSELLC--EFPERLRGESLRHLNPAMMGCTHADPRKQALIGALLVGSAATITALALVLY 463

  Fly   514 KCLRDLQETKAQGI 527
            :|...::||...|:
  Fly   464 RCRHKIRETIKGGL 477

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32055	NP_729599.1	leucine-rich repeat	76..99	CDD:275380
		leucine-rich repeat	100..123	CDD:275380	5/13 (38%)
		LRR_8	128..180	CDD:290566	11/51 (22%)
		leucine-rich repeat	128..147	CDD:275380	3/18 (17%)
		leucine-rich repeat	148..171	CDD:275380	5/22 (23%)
		leucine-rich repeat	172..192	CDD:275380	4/19 (21%)
		LRR_RI	<187..400	CDD:238064	68/245 (28%)
		LRR_8	192..251	CDD:290566	23/66 (35%)
		leucine-rich repeat	193..216	CDD:275380	8/30 (27%)
		leucine-rich repeat	217..240	CDD:275380	9/22 (41%)
		leucine-rich repeat	241..267	CDD:275380	7/26 (27%)
		leucine-rich repeat	268..291	CDD:275380	5/22 (23%)
		LRR_8	290..350	CDD:290566	20/59 (34%)
		leucine-rich repeat	292..315	CDD:275380	8/22 (36%)
		leucine-rich repeat	316..339	CDD:275380	6/22 (27%)
		LRR_8	340..400	CDD:290566	20/83 (24%)
		leucine-rich repeat	340..365	CDD:275380	9/36 (25%)
		leucine-rich repeat	366..389	CDD:275380	8/34 (24%)
		leucine-rich repeat	390..413	CDD:275380	8/22 (36%)
		LRR_8	391..448	CDD:290566	14/56 (25%)
		leucine-rich repeat	414..437	CDD:275380	6/22 (27%)
trn	NP_001261796.1	leucine-rich repeat	62..80	CDD:275380	3/20 (15%)
		LRR_8	83..142	CDD:290566	16/63 (25%)
		leucine-rich repeat	84..107	CDD:275380	5/22 (23%)
		leucine-rich repeat	108..131	CDD:275380	6/27 (22%)
		LRR_RI	129..421	CDD:238064	86/322 (27%)
		LRR_8	132..190	CDD:290566	20/57 (35%)
		leucine-rich repeat	132..155	CDD:275380	6/22 (27%)
		leucine-rich repeat	156..179	CDD:275380	9/22 (41%)
		leucine-rich repeat	180..204	CDD:275380	7/23 (30%)
		LRR_8	203..263	CDD:290566	19/62 (31%)
		leucine-rich repeat	205..228	CDD:275380	6/25 (24%)
		leucine-rich repeat	229..252	CDD:275380	8/22 (36%)
		LRR_8	252..308	CDD:290566	13/55 (24%)
		leucine-rich repeat	253..276	CDD:275380	6/22 (27%)
		leucine-rich repeat	277..300	CDD:275380	5/22 (23%)
		leucine-rich repeat	301..322	CDD:275380	4/20 (20%)
		LRR_8	325..384	CDD:290566	21/59 (36%)
		leucine-rich repeat	326..350	CDD:275380	8/23 (35%)
		leucine-rich repeat	351..373	CDD:275380	8/22 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45472907
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24373
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940