DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32055 and CG7509

DIOPT Version :9

Sequence 1:	NP_729599.1	Gene:	CG32055 / 39188	FlyBaseID:	FBgn0052055	Length:	534	Species:	Drosophila melanogaster
Sequence 2:	NP_647931.1	Gene:	CG7509 / 38579	FlyBaseID:	FBgn0035575	Length:	615	Species:	Drosophila melanogaster

Alignment Length:	531	Identity:	140/531 - (26%)
Similarity:	220/531 - (41%)	Gaps:	76/531 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 LLLSGVFGKDLQECEDLGNGSYLCREIESFEQLNRYVGKNWKSVK-VVNEHTGIERAEDGELPGL 73
            |:.|......|..||.||..|.|...|.|.....:....:.|..| ..|.|...: ...||:..:
  Fly    46 LISSDTRNCSLNACESLGIVSQLLMLINSMPNGTQSAANDKKPPKSKANGHNDGD-VNGGEINAM 109

  Fly    74 STLLQLDLSESGGVTLGEKGLQDFKALQKLNLTHAQLDELKSEQFP------------------- 119
            |.|...||               .|.::::.      ..|:|.:.|
  Fly   110 SHLANFDL---------------VKRVRQIE------SRLRSVEQPVWHLATGSQIEWNHCTSGV 153

  Fly   120 ---NPSEMINFDVSYNDILAI-TTKLMSGFGNLVYANFSENLIAVIEPNAFRHMKNLRFLDLTTN 180
               || :..:|.....::.:: .|:::.  .|:|..:.|.|:::.:..:.||.:..|:.||::.|
  Fly   154 CRCNP-DTKSFTCWNTNLKSVPVTQVIP--MNMVNIDLSRNILSTLHKDTFRGLTVLKELDISHN 215

  Fly   181 YQENITLG---ENANLRFLSISNNNLRDFQWCHLRVLPKLEELHLHSNWLEHLDMGIFYALPNLR 242
            ..:.:...   :..:|..|.|.||.|.|........|..|..|.|..|.:..|...|||....|.
  Fly   216 VLDFLPFDLFQDLDSLLVLRIQNNQLEDIDHRTFWKLRNLNILDLSKNEIGMLPESIFYHAQRLT 280

  Fly   243 VLNVSNNNLFEIKRTLFMAPGEIAPLELLDYSSNIVKVLDDSVFCRLKKLRTLNLWLNQINRIHP 307
            |:|:.:|.:......|..   :...||.||.|.|.:..|.......|.||:||:...|||.:|..
  Fly   281 VINMCDNQIQNFPPNLLR---DQLMLEELDMSRNKISELSSGSIRYLTKLKTLDFGWNQIAKIDD 342

  Fly   308 RAFLGLSSLQTLHLQGNKISILPDDVFANLTALEKLDLSKNNIQKLGLRVFGERILRKLIYLDLS 372
            ..|.||.||:||.|..|:||.|...:|.||..|..|||:.|.|..:....|.|  |..|..|.|.
  Fly   343 DFFAGLRSLRTLSLHNNRISSLSGTIFNNLANLVTLDLTTNRISHIDGNAFVE--LNNLNELFLG 405

  Fly   373 NNYIADLHPLALSSMPFIKELRLRRNRLVSLDLRMFAPLRQLQLLTINENRLEEIDGEILDTLDR 437
            .|.::.:......::..:..|.|..|.|.:|:...|..|..|::|.:|.|.|:..|....:.|.:
  Fly   406 QNSMSSIPADLFLNVSALTRLTLFSNNLTTLEADDFQGLNNLKILLLNNNILKNFDARAFEPLSQ 470

  Fly   438 LNHLELNNNRLTFLPD--LKSSQNLLQLRNITLEGNPWQCLCLDEITSWLNGRHVSYARPSSAY- 499
            |..|.:::|:|.|||.  |...:||:.::   |:.|||.|.|          |.:..||....:
  Fly   471 LEKLRIDSNKLMFLPHGALHGLKNLVAVK---LDKNPWHCDC----------RALYLARWIREFV 522

  Fly   500 ---FSGRKPLC 507
               :.|::|:|
  Fly   523 LKLWDGQQPMC 533

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32055	NP_729599.1	leucine-rich repeat	76..99	CDD:275380	3/22 (14%)
		leucine-rich repeat	100..123	CDD:275380	5/44 (11%)
		LRR_8	128..180	CDD:290566	10/52 (19%)
		leucine-rich repeat	128..147	CDD:275380	1/19 (5%)
		leucine-rich repeat	148..171	CDD:275380	5/22 (23%)
		leucine-rich repeat	172..192	CDD:275380	4/22 (18%)
		LRR_RI	<187..400	CDD:238064	68/215 (32%)
		LRR_8	192..251	CDD:290566	20/58 (34%)
		leucine-rich repeat	193..216	CDD:275380	8/22 (36%)
		leucine-rich repeat	217..240	CDD:275380	8/22 (36%)
		leucine-rich repeat	241..267	CDD:275380	5/25 (20%)
		leucine-rich repeat	268..291	CDD:275380	8/22 (36%)
		LRR_8	290..350	CDD:290566	28/59 (47%)
		leucine-rich repeat	292..315	CDD:275380	10/22 (45%)
		leucine-rich repeat	316..339	CDD:275380	11/22 (50%)
		LRR_8	340..400	CDD:290566	16/59 (27%)
		leucine-rich repeat	340..365	CDD:275380	9/24 (38%)
		leucine-rich repeat	366..389	CDD:275380	4/22 (18%)
		leucine-rich repeat	390..413	CDD:275380	7/22 (32%)
		LRR_8	391..448	CDD:290566	17/56 (30%)
		leucine-rich repeat	414..437	CDD:275380	7/22 (32%)
CG7509	NP_647931.1	LRR_8	182..241	CDD:290566	15/58 (26%)
		leucine-rich repeat	187..206	CDD:275380	4/18 (22%)
		LRR_RI	<201..386	CDD:238064	63/187 (34%)
		leucine-rich repeat	207..230	CDD:275380	4/22 (18%)
		leucine-rich repeat	231..254	CDD:275380	8/22 (36%)
		LRR_8	253..313	CDD:290566	19/62 (31%)
		leucine-rich repeat	255..278	CDD:275380	8/22 (36%)
		leucine-rich repeat	279..302	CDD:275380	5/25 (20%)
		LRR_8	303..361	CDD:290566	25/57 (44%)
		leucine-rich repeat	303..326	CDD:275380	8/22 (36%)
		leucine-rich repeat	327..350	CDD:275380	10/22 (45%)
		LRR_8	349..407	CDD:290566	24/59 (41%)
		LRR_4	350..390	CDD:289563	18/39 (46%)
		leucine-rich repeat	351..374	CDD:275380	11/22 (50%)
		leucine-rich repeat	375..398	CDD:275380	9/24 (38%)
		LRR_8	398..>443	CDD:290566	10/44 (23%)
		leucine-rich repeat	399..422	CDD:275380	4/22 (18%)
		leucine-rich repeat	423..443	CDD:275380	6/19 (32%)
		leucine-rich repeat	471..494	CDD:275380	8/22 (36%)
		LRRCT	503..554	CDD:214507	11/41 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	56	1.000	Inparanoid score	I440
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24373
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	3.060