DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32055 and Cd180

DIOPT Version :9

Sequence 1:	NP_729599.1	Gene:	CG32055 / 39188	FlyBaseID:	FBgn0052055	Length:	534	Species:	Drosophila melanogaster
Sequence 2:	NP_001099875.1	Gene:	Cd180 / 294706	RGDID:	1308170	Length:	662	Species:	Rattus norvegicus

Alignment Length:	611	Identity:	131/611 - (21%)
Similarity:	226/611 - (36%)	Gaps:	164/611 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 ALQVLALLLLSGVFGKDLQECEDLGNGSYLCREIESFEQLNRYVGKNWKSVKVVNEHTGIERAED 67
            ||.:...||:: :|.   ..|:.:|:....|.|.|        |.|.:..     ||.|:
  Rat     2 ALDISCFLLVA-LFS---ASCQAIGSSDQRCTEKE--------VNKTYNC-----EHLGL----- 44

  Fly    68 GELPGL--STLLQLDLSESGGVTLGEKGLQDFKALQKLNLTHAQLDELKSEQFPNPSEMINFDVS 130
            .|:||.  ::...|:.|.:...|:.:........|..|:||..|:..:..:.|.:...:....::
  Rat    45 SEIPGTLPNSTESLEFSFNALPTIQKTTFSRLVNLTFLDLTRCQIYWIHEDTFQSQHRLETLVLT 109

  Fly   131 YNDILAITTKLMSGFGNLVYANFSENLIAVIEPNAFRHMKNLRFLDLTTNYQENITLGEN---AN 192
            .|.::.:....::|...|.:..|.:..|:.||.......|.|..|.|.:|:..:|.|.::   ..
  Rat   110 ANPLIFMAETALTGPKALKHLFFIQTGISSIEFIPVHSQKALESLYLGSNHISSIRLPKDFPTEK 174

  Fly   193 LRFLSISNN---------------------NLRD---------------FQWCH-------LRVL 214
            |:.|...||                     ||..               ||..:       |.:.
  Rat   175 LKVLDFQNNAIHHLSKEDVSSLQQATNLSLNLNGNDITGIEPGAFKSTVFQSLNFGGTQSLLVIF 239

  Fly   215 PKLEELHLHSNWL---------EHLDMGIFYALPNLRV--LNVSNNNLFEIKRTLFMAPGEIAPL 268
            ..|:...:.|.||         |.:...:|..|..:.|  :|:..::.|.|....|..   .:.|
  Rat   240 KGLQNSTIQSLWLGTFEDIDDDEDISSSMFEGLCEMSVERINLQKHHFFNITSNTFYC---FSGL 301

  Fly   269 ELLDYSSNIVKVLDDSVFCRLKKLRTLNLWLNQINRIHPRAFLGLSSLQTLHLQGN--------- 324
            :.||.::..:..|...: ..|.||:.|.|..|:...:...:.....||..|:::||
  Rat   302 QELDLTATHLTELPSGI-VGLSKLKKLVLSANKFENLCQISASNFPSLTHLYIKGNTKRLELGSG 365

  Fly   325 ---------KISILPDDV---------FANLTALEKLDLSKNNIQKLGLRVFGERILRKLIYLDL 371
                     ::.:..||:         ..||:.|:.|:||.|  :.||||....:...:|..|||
  Rat   366 CLETLEHLRELDLSHDDIETSDCCNLQLRNLSHLQSLNLSYN--EPLGLRTEAFKECPQLELLDL 428

  Fly   372 ---------SNNYIADLHPL----------------ALSSMPFIKELRLRRNRLVSLDLRMFAPL 411
                     :.:...:||.|                .|..:|.::.|.|:.||..:.:::...||
  Rat   429 AFTRLHVKDAQSPFQNLHLLKVLNLSHCLLGSSNQHLLDGLPALRHLNLQGNRFPNGNIQKTNPL 493

  Fly   412 R---QLQLLTINENRLEEIDGEILDTLDRLNHLELNNNRLT-----FLPDLKS-----SQN---- 459
            :   .|::|.::...|..||.:....|..:||::|::||||     .|..||.     :.|
  Rat   494 QALGSLEILILSFCDLSSIDHQAFINLKIMNHVDLSHNRLTSSSIEALSHLKGIYLNLASNRISI 558

  Fly   460 --------LLQLRNITLEGNPWQCLC 477
                    |.|.|.|.|..||..|.|
  Rat   559 IPPSLLPVLSQQRTINLRQNPLDCTC 584

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32055	NP_729599.1	leucine-rich repeat	76..99	CDD:275380	3/22 (14%)
		leucine-rich repeat	100..123	CDD:275380	6/22 (27%)
		LRR_8	128..180	CDD:290566	11/51 (22%)
		leucine-rich repeat	128..147	CDD:275380	2/18 (11%)
		leucine-rich repeat	148..171	CDD:275380	5/22 (23%)
		leucine-rich repeat	172..192	CDD:275380	6/22 (27%)
		LRR_RI	<187..400	CDD:238064	62/321 (19%)
		LRR_8	192..251	CDD:290566	18/112 (16%)
		leucine-rich repeat	193..216	CDD:275380	9/65 (14%)
		leucine-rich repeat	217..240	CDD:275380	7/31 (23%)
		leucine-rich repeat	241..267	CDD:275380	5/27 (19%)
		leucine-rich repeat	268..291	CDD:275380	5/22 (23%)
		LRR_8	290..350	CDD:290566	19/86 (22%)
		leucine-rich repeat	292..315	CDD:275380	4/22 (18%)
		leucine-rich repeat	316..339	CDD:275380	8/49 (16%)
		LRR_8	340..400	CDD:290566	21/84 (25%)
		leucine-rich repeat	340..365	CDD:275380	9/24 (38%)
		leucine-rich repeat	366..389	CDD:275380	8/47 (17%)
		leucine-rich repeat	390..413	CDD:275380	6/25 (24%)
		LRR_8	391..448	CDD:290566	16/59 (27%)
		leucine-rich repeat	414..437	CDD:275380	6/22 (27%)
Cd180	NP_001099875.1	leucine-rich repeat	55..78	CDD:275380	3/22 (14%)
		leucine-rich repeat	79..102	CDD:275380	6/22 (27%)
		leucine-rich repeat	103..126	CDD:275380	2/22 (9%)
		leucine-rich repeat	127..150	CDD:275380	5/22 (23%)
		leucine-rich repeat	151..174	CDD:275380	6/22 (27%)
		leucine-rich repeat	175..195	CDD:275380	4/19 (21%)
		leucine-rich repeat	196..223	CDD:275380	2/26 (8%)
		leucine-rich repeat	224..244	CDD:275380	4/19 (21%)
		leucine-rich repeat	277..300	CDD:275380	5/25 (20%)
		LRR_RI	301..480	CDD:238064	39/181 (22%)
		leucine-rich repeat	301..323	CDD:275380	5/22 (23%)
		LRR_8	322..383	CDD:290566	11/60 (18%)
		leucine-rich repeat	324..347	CDD:275380	4/22 (18%)
		leucine-rich repeat	348..372	CDD:275380	4/23 (17%)
		LRR_8	372..433	CDD:290566	17/62 (27%)
		leucine-rich repeat	373..398	CDD:275380	4/24 (17%)
		leucine-rich repeat	399..422	CDD:275380	9/24 (38%)
		LRR_8	421..482	CDD:290566	12/60 (20%)
		leucine-rich repeat	423..447	CDD:275380	5/23 (22%)
		leucine-rich repeat	448..471	CDD:275380	2/22 (9%)
		leucine-rich repeat	472..498	CDD:275380	6/25 (24%)
		LRR_8	498..556	CDD:290566	17/57 (30%)
		leucine-rich repeat	499..522	CDD:275380	6/22 (27%)
		leucine-rich repeat	523..546	CDD:275380	9/22 (41%)
		TPKR_C2	578..627	CDD:301599	4/7 (57%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910