DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32055 and Cd180

DIOPT Version :9

Sequence 1:	NP_729599.1	Gene:	CG32055 / 39188	FlyBaseID:	FBgn0052055	Length:	534	Species:	Drosophila melanogaster
Sequence 2:	NP_032559.2	Gene:	Cd180 / 17079	MGIID:	1194924	Length:	661	Species:	Mus musculus

Alignment Length:	389	Identity:	105/389 - (26%)
Similarity:	153/389 - (39%)	Gaps:	110/389 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    97 FKALQKLNLTHAQLDELKSEQFPNPSEMINFDVSYNDILAITTKLMSGFGNLVYANFSENLIAVI 161
            |..||:|:||...|.||       ||.::.        |:...||      ::.||..|||..:.
Mouse   297 FSGLQELDLTATHLSEL-------PSGLVG--------LSTLKKL------VLSANKFENLCQIS 340

  Fly   162 EPN--AFRHMK---NLRFLDLTTNYQENITLGENANLRFLSISNNNLRDFQWCHLRVLPKLEELH 221
            ..|  :..|:.   |.:.|:|.|...||:     .|||.|.:|::::.....|:|::
Mouse   341 ASNFPSLTHLSIKGNTKRLELGTGCLENL-----ENLRELDLSHDDIETSDCCNLQL-------- 392

  Fly   222 LHSNWLEHLDMGIFYALPNLRVLNVSNNNLFEIKRTLFMAPGEIAPLELLDYSSNIVKVLD-DSV 285
                          ..|.:|:.||:|.|....:|...|.   |...|||||.:...:||.| .|.
Mouse   393 --------------RNLSHLQSLNLSYNEPLSLKTEAFK---ECPQLELLDLAFTRLKVKDAQSP 440

  Fly   286 FCRLKKLRTLNLWLNQINRIHPRAFLGLSSLQTLHLQGNKISILPDDVFANLTALEKLDLSKNNI 350
            |..|..|:.|||..:.::....:.|.||.:||.|:||||                   ...|.||
Mouse   441 FQNLHLLKVLNLSHSLLDISSEQLFDGLPALQHLNLQGN-------------------HFPKGNI 486

  Fly   351 QKL-GLRVFGERILRKLIYLDLSNNYIADLHPLALSSMPFIKELRLRRNRLVSLDLRMFAPLRQL 414
            ||. .|:..|...:..|.:.|||                             |:|...|..|:.:
Mouse   487 QKTNSLQTLGRLEILVLSFCDLS-----------------------------SIDQHAFTSLKMM 522

  Fly   415 QLLTINENRLEEIDGEILDTLDRLNHLELNNNRLT-FLPDLKSSQNLLQLRNITLEGNPWQCLC 477
            ..:.::.|||.....|.|..|..: :|.|.:||:: .||.|...  |.|.|.|.|..||..|.|
Mouse   523 NHVDLSHNRLTSSSIEALSHLKGI-YLNLASNRISIILPSLLPI--LSQQRTINLRQNPLDCTC 583

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32055	NP_729599.1	leucine-rich repeat	76..99	CDD:275380	1/1 (100%)
		leucine-rich repeat	100..123	CDD:275380	9/22 (41%)
		LRR_8	128..180	CDD:290566	13/56 (23%)
		leucine-rich repeat	128..147	CDD:275380	3/18 (17%)
		leucine-rich repeat	148..171	CDD:275380	7/27 (26%)
		leucine-rich repeat	172..192	CDD:275380	5/19 (26%)
		LRR_RI	<187..400	CDD:238064	52/214 (24%)
		LRR_8	192..251	CDD:290566	13/58 (22%)
		leucine-rich repeat	193..216	CDD:275380	6/22 (27%)
		leucine-rich repeat	217..240	CDD:275380	1/22 (5%)
		leucine-rich repeat	241..267	CDD:275380	8/25 (32%)
		leucine-rich repeat	268..291	CDD:275380	11/23 (48%)
		LRR_8	290..350	CDD:290566	15/59 (25%)
		leucine-rich repeat	292..315	CDD:275380	7/22 (32%)
		leucine-rich repeat	316..339	CDD:275380	7/22 (32%)
		LRR_8	340..400	CDD:290566	11/60 (18%)
		leucine-rich repeat	340..365	CDD:275380	7/25 (28%)
		leucine-rich repeat	366..389	CDD:275380	4/22 (18%)
		leucine-rich repeat	390..413	CDD:275380	4/22 (18%)
		LRR_8	391..448	CDD:290566	13/56 (23%)
		leucine-rich repeat	414..437	CDD:275380	6/22 (27%)
Cd180	NP_032559.2	leucine-rich repeat	38..57	CDD:275380
		LRR 1	54..75
		leucine-rich repeat	58..78	CDD:275380
		LRR 2	78..99
		leucine-rich repeat	79..102	CDD:275380
		LRR 3	102..123
		leucine-rich repeat	103..126	CDD:275380
		LRR 4	126..147
		leucine-rich repeat	127..150	CDD:275380
		LRR 5	150..171
		leucine-rich repeat	151..174	CDD:275380
		LRR 6	174..195
		leucine-rich repeat	175..201	CDD:275380
		LRR 7	201..221
		leucine-rich repeat	224..275	CDD:275380
		LRR 8	275..296
		leucine-rich repeat	276..299	CDD:275380	1/1 (100%)
		LRR 9	299..321		10/36 (28%)
		leucine-rich repeat	300..322	CDD:275380	11/36 (31%)
		LRR_8	321..382	CDD:290566	20/71 (28%)
		LRR 10	322..343		7/26 (27%)
		leucine-rich repeat	323..346	CDD:275380	8/28 (29%)
		LRR_RI	345..>541	CDD:238064	67/273 (25%)
		LRR 11	346..366		5/19 (26%)
		leucine-rich repeat	347..371	CDD:275380	7/28 (25%)
		LRR_8	371..432	CDD:290566	21/85 (25%)
		LRR 12	371..391		6/19 (32%)
		leucine-rich repeat	372..397	CDD:275380	7/46 (15%)
		LRR 13	397..418		7/23 (30%)
		leucine-rich repeat	398..421	CDD:275380	8/25 (32%)
		LRR_8	420..481	CDD:290566	25/79 (32%)
		LRR 14	421..442		9/20 (45%)
		leucine-rich repeat	422..446	CDD:275380	11/23 (48%)
		LRR 15	446..466		4/19 (21%)
		leucine-rich repeat	447..470	CDD:275380	7/22 (32%)
		LRR 16	470..493		12/41 (29%)
		leucine-rich repeat	471..497	CDD:275380	13/44 (30%)
		LRR_8	497..555	CDD:290566	17/87 (20%)
		LRR 17	497..518		7/49 (14%)
		leucine-rich repeat	498..521	CDD:275380	8/51 (16%)
		LRR 18	521..544		5/22 (23%)
		leucine-rich repeat	522..545	CDD:275380	6/22 (27%)
		LRR 19	546..566		7/22 (32%)
		LRRCT	577..626	CDD:214507	4/7 (57%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910